National Xenopus Resource Center

国家爪蟾资源中心

• 批准号: 10155609
• 负责人: Marko E Horb
• 金额: $ 63.16万
• 依托单位: MARINE BIOLOGICAL LABORATORY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-12 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10155609
• 关键词: Animal Housing; Animals; Back; Bioinformatics; Biological; Breeding; Communities; Custom; Educational process of instructing; Educational workshop; Ensure; Fertilization in Vitro; Gene Transfer Techniques; Goals; Grant; Housing; Image; Inbreeding; Individual; Infrastructure; Institutes; Institution; Laboratories; Maintenance; Progress Reports; Rana; Research; Research Personnel; Resources; Scientist; Services; Site; Technology; Training; Transgenic Organisms; United States National Institutes of Health; Veterinarians; Visit; XenBase; Xenopus; Xenopus laevis; animal care; animal resource; genome editing; male; meetings; mutant; new technology; novel; pathogen; repository; research facility; sperm cryopreservation; training opportunity

Project Summary – Core Component This component outlines the various resources available to the community at the National Xenopus Resource (NXR) and a detailed progress report of the previous five years. We outline the infrastructure of the facility, describing the two main rooms housing X. laevis and X. tropicalis as well as the new room that was renovated in 2017. We provide a summary of the maintenance, breeding and distribution of frogs to the community. In the second aim we summarize the various resources and services available to the community, including cryopreserved sperm and the custom transgenesis and mutant resources that serve to enhance research using Xenopus through facilitating the creation of new frog lines that is often an impediment in the community because of the inability of individual labs to breed lines in their own institution. In the third aim, we describe how the NXR enhances novel Xenopus research through its offering of advanced training workshops, hosting of PI meetings and its research facility service. All of these aspects are made possible by the various facilities available at the Marine Biological Laboratory, including teaching labs, imaging core and on-site housing.

项目摘要 - 核心组成部分 该组成部分概述了国家Xenopus资源的社区可用的各种资源 （NXR）和前五年的详细进度报告。我们概述了设施的基础设施， 描述两个主要房间的住房X. Laevis和X. Tropicalis以及已翻新的新房间 在2017年。我们提供了青蛙对社区的维护，繁殖和分配的摘要。在 第二目的我们总结了社区可用的各种资源和服务，包括 冷冻保存的精子以及自定义转基因和突变资源，用于增强研究 Xenopus通过促进创建新的青蛙线条，这通常是社区中的障碍 单个实验室无法在自己的机构中繁殖线路的原因。在第三个目标中，我们描述了NXR如何 通过提供高级培训研讨会，举办PI会议来增强新颖的Xenopus研究 及其研究设施服务。所有这些方面都是由可用的各种设施使 海洋生物实验室，包括教学实验室，成像核心和现场外壳。