National Xenopus Resource Center
National Xenopus Resource Center
批准号:
10661157
负责人:
Marko E Horb
金额:
$28.57万
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
未结题
起止时间:
2010-08-12 至 2025-04-30
关键词:
Animal HousingAnimalsApplied ResearchBioinformaticsCodeCommunitiesCustomDNA Sequence AlterationEducational workshopEnsureGenesGrantImageIndividualInstitutesLightMapsMethodsMusMutationReproducibilityResearchResearch PersonnelResourcesSalesServicesSiteTechnologyTransgenesTransgenic MiceTransgenic OrganismsUnited States National Institutes of HealthWorkXenBaseXenopusgenome editingintegration sitemeetingsmutantrepositoryresearch facility
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Project Summary – Project Component
The Project Component outlines the applied research of the National Xenopus Resource (NXR). Transgenic
lines are the single largest component of the NXR. These lines are essential for individual labs and their sales
are increasing each year. In recent years, it has been shown that in most mouse transgenic lines there are
genomic alterations in and around the integration sites of transgenes. These changes can influence the
expression of endogenous genes or even cause mutations in these genes. Therefore, it is essential that we
define the integration sites for our transgenic lines. In this Component we outline the steps we will take to identify
the integration sites for five of our transgenic lines.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
XenCAT: Xenopus Single Cell Atlas
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批准号:10669806
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项目类别:
-
资助金额:$79.28万
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财政年份:2022
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负责人:Marko E Horb
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依托单位:
XenCAT: Xenopus Single Cell Atlas
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批准号:10807246
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项目类别:
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资助金额:$24.88万
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财政年份:2022
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负责人:Marko E Horb
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依托单位:
Xenopus Mutant Resource
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批准号:10206289
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项目类别:
-
资助金额:$77.68万
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财政年份:2020
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负责人:Marko E Horb
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依托单位:
Xenopus Mutant Resource
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批准号:10644188
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项目类别:
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资助金额:$16.09万
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财政年份:2020
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负责人:Marko E Horb
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依托单位:
Xenopus Mutant Resource
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批准号:10047403
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项目类别:
-
资助金额:$79.36万
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财政年份:2020
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负责人:Marko E Horb
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依托单位:
Xenopus Mutant Resource
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批准号:10435421
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项目类别:
-
资助金额:$75.8万
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财政年份:2020
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负责人:Marko E Horb
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依托单位:
Xenopus Mutant Resource
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批准号:10455298
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项目类别:
-
资助金额:$22.94万
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财政年份:2020
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负责人:Marko E Horb
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依托单位:
Xenopus Mutant Resource
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批准号:10646475
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项目类别:
-
资助金额:$74.01万
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财政年份:2020
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负责人:Marko E Horb
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依托单位:
Xenopus Mutant Resource
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批准号:10807617
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项目类别:
-
资助金额:$23.62万
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财政年份:2020
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负责人:Marko E Horb
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依托单位:
Enhancing CRISPR-Cas for disease modeling in Xenopus
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批准号:9900078
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项目类别:
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资助金额:$20.75万
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财政年份:2019
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负责人:Marko E Horb
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依托单位:
Xenopus models of human disease by targeted genome editing
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批准号:9257431
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项目类别:
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资助金额:$58.31万
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财政年份:2015
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负责人:Marko E Horb
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依托单位:
National Xenopus Resource Center
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批准号:10394273
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项目类别:
-
资助金额:$61.35万
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财政年份:2010
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负责人:Marko E Horb
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依托单位:
National Xenopus Resource Center
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批准号:10155609
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项目类别:
-
资助金额:$63.16万
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财政年份:2010
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负责人:Marko E Horb
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依托单位:
National Xenopus Resource Center
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批准号:10155608
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项目类别:
-
资助金额:$69.77万
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财政年份:2010
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负责人:Marko E Horb
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依托单位:
National Xenopus Resource Center
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批准号:10621146
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项目类别:
-
资助金额:$59.48万
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财政年份:2010
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负责人:Marko E Horb
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依托单位:
National Xenopus Resource Center
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批准号:10155610
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项目类别:
-
资助金额:$6.61万
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财政年份:2010
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负责人:Marko E Horb
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依托单位:
National Xenopus Resource Center
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批准号:10621151
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项目类别:
-
资助金额:$6.61万
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财政年份:2010
-
负责人:Marko E Horb
-
依托单位:
National Xenopus Resource Center
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批准号:10609622
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项目类别:
-
资助金额:$28.57万
-
财政年份:2010
-
负责人:Marko E Horb
-
依托单位:
National Xenopus Resource Center
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批准号:10394274
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项目类别:
-
资助金额:$6.61万
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财政年份:2010
-
负责人:Marko E Horb
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依托单位:
National Xenopus Resource Center
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批准号:10405208
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项目类别:
-
资助金额:$20.12万
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财政年份:2010
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负责人:Marko E Horb
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依托单位:
海外基金