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中文摘要
翻译
生物医学研究企业的成功取决于具有多种多样的科学家的强大管道 专业知识,在临床和转化科学(CTS)的核心能力训练有素。这方面的主要威胁 管道包括现代研究人员的需求和狭窄的培训之间的不匹配 获得了大多数生物医学博士学位。此外,临床医生面临着越来越困难的过渡, 稳定的职业发展资金,无需严格的研究培训。近二十年来,塔夫茨 萨克勒CTS研究生项目是塔夫茨CTSI的培训核心,成功地培养了临床科学家 跨翻译研究的频谱,强调翻译的后期阶段(T2-T4)与广泛的 对健康的影响通过此次CTSA续约,我们将大幅扩展和增强我们的TL 1计划 与塔夫茨CTSI的增长相称,以满足更大的培训需求,建立在 卓越的MS/PhD CTS计划,通过以下目标:目的1)我们将提供严格的培训, CTS的核心竞争力,以不同的学者,包括更多的博士培养的生物医学科学家。我们 将利用扩大的合作伙伴关系塔夫茨CTSI,包括塔夫茨大学萨克勒学院, 杰克逊实验室、马萨诸塞州理工学院(MIT)和东北大学,以及一个 加强与塔夫茨弗里德曼营养科学与政策学院的联系。2、我们将扩大 指导和研究经验,以加强TL 1研究员和所有 CTS研究生课程的学生。这将包括提供四个专门的TL 1轨道,强调 机构优势:比较有效性研究;一个健康;药物和器械开发; 卫生政策。我们还将建立创新的研究实习-在合作机构和周围 波士顿丰富的生物技术中心-和新的研讨会和工作室的主题,成功的现代 翻译团队,包括利益相关者/社区参与,团队科学,严谨性和透明度, 学术界与工业界的合作以及临床试验创新。我们将装备临床科学家和生物医学 博士科学家与必要的技能和经验,成功的环境,已转移到 广泛参与,以团队为基础的翻译研究。
英文摘要
The success of the biomedical research enterprise depends upon a robust pipeline of scientists with diverse expertise, well-trained in the core competencies of clinical and translational science (CTS). Major threats to this pipeline include the mismatch between the needs of the modern research workforce and the narrow training received in most biomedical PhD programs. Additionally, clinicians face an increasingly difficult transition to stable career development funding without rigorous research training. For almost two decades, the Tufts Sackler CTS Graduate Program, the training core of Tufts CTSI, has successfully trained clinician-scientists across the spectrum of translational research, emphasizing later stages of translation (T2-T4) with a broad impact on health. With this CTSA renewal, we will substantially expand and enhance our TL1 Program commensurate to the growth of Tufts CTSI to meet the larger training needs, building on the history of excellence in our MS/PhD CTS Program, by the following aims: AIM 1) we will provide rigorous training in the core competencies of CTS to a diverse set of scholars, including more PhD-trained biomedical scientists. We will leverage the broadened partnerships of the Tufts CTSI, including the Tufts University Sackler School, the Jackson Laboratory, the Massachusetts Institute of Technology (MIT), and Northeastern University, and a strengthened connection to the Tufts Friedman School of Nutrition Science and Policy. AIM 2) we will expand the mentoring and research experiences to enhance the individual development plans of TL1 fellows and all CTS Graduate Program students. This will include offering four specialized TL1 tracks, emphasizing institutional strengths: Comparative Effectiveness Research; One Health; Drug and Device Development; Health Policy. We will also establish innovative research externships – based at partner institutions and around Boston’s rich biotech hub – and new seminars and studios on topics critical for success in the modern translational workforce, including stakeholder/community engagement, team science, rigor and transparency, academic-industry partnerships, and clinical trial innovations. We will equip clinician-scientists and biomedical PhD scientists with the skills and experience necessary to succeed in an environment that has shifted to broadly-engaged, team-based translational research.
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CTSA Predoctoral T32 at Tufts University
  • 批准号:
    10621977
  • 项目类别:
  • 资助金额:
    $54.35万
  • 财政年份:
    2023
  • 负责人:
    DAVID M KENT
  • 依托单位:
Covert Cerebrovascular Disease Detected by Artificial Intelligence (C2D2AI): A Platform for Pragmatic Evidence Generation for Stroke and Dementia Prevention
  • 批准号:
    10591063
  • 项目类别:
  • 资助金额:
    $289.48万
  • 财政年份:
    2023
  • 负责人:
    DAVID M KENT
  • 依托单位:
CTSA Postdoctoral T32 at Tufts University
  • 批准号:
    10621976
  • 项目类别:
  • 资助金额:
    $52.15万
  • 财政年份:
    2023
  • 负责人:
    DAVID M KENT
  • 依托单位:
CTSA Graduate Program
  • 批准号:
    10396575
  • 项目类别:
  • 资助金额:
    $91.99万
  • 财政年份:
    2018
  • 负责人:
    DAVID M KENT
  • 依托单位:
海外基金