Tufts CTSI Career Development Program in Comparative Effectiveness Research

描述(申请人提供)：自2008年成立以来，塔夫茨临床和翻译研究所(CTSI)的一个主要目标是为有效开展比较有效性研究(CER)、开发创新的CER方法以及培训CER研究员和学者建立一个全面的基础设施。基于这一领域的悠久传统，塔夫茨CTSI将一系列非凡的学科、新颖的方法和合作研究机会联系在一起，专注于“床边到实践”和“实践到政策”的翻译研究，并基于这些资产和这一重点，在协调国家CTSA联盟的反应方面发挥了领导作用。很明显，CER需要提供关于竞争性治疗方案的相对收益和成本的现成和可操作的信息，这远远超过了塔夫茨CTSI等学术研究中心的总体能力，美国在CER方面的专业知识和能力主要位于塔夫茨CTSI。迫切需要国家投入大量资金培训下一代CER研究人员，以及学术中心承诺优先开展CER培训。塔夫茨CTSI做好了充分的准备，以扩大我们在CER领域培训领导者和创新者的角色，增强我们的核心CER能力，帮助满足这些关键需求。通过这项申请，我们的目标是在CER建立一个有指导的职业发展计划，该计划基于我们在整个CER领域的研究专业知识的广度和深度，以及我们培训CER学者的悠久历史，以及我们与社区和行业利益相关者的牢固联系。该培训计划的目的是：1)培养领导者和创新者，以帮助应对国家未来十年巨大的CER挑战和劳动力需求；2)(因为CER是以团队合作的形式进行的)进一步加强塔夫茨CTSI作为CER卓越中心的地位。 公共卫生相关性：临床医生、患者和付款人每天都需要准确和可操作的信息来做出无数重要的医疗保健决策。然而，通常情况下，这些信息是不可用的。为了提供这些信息，我们需要关于治疗价值的高质量比较有效性研究。这一应用是为了在比较有效性研究方面为下一代领导者和创新者提供培训。

DESCRIPTION (provided by applicant): From its inception in 2008, a major goal of the Tufts Clinical and Translational Institute (CTSI) has been to develop a comprehensive infrastructure for the efficient conduct of comparative effectiveness research (CER), the development of innovative CER methods, and the training of fellows and scholars in CER. Based on a long tradition in this area, the Tufts CTSI has linked an extraordinary array of disciplines, novel methods and collaborative research opportunities focused on "bedside-to-practice" and "practice-to-policy" translational research and, based on these assets and this focus, has played a leadership role in coordinating the response of the National CTSA Consortium. It has been clear that the need for CER to provide readily available and actionable information on the relative benefits and costs of competing treatment options far outstrips the collective capacity of academic research centers like the Tufts CTSI, where the nation's expertise and capacity for CER largely resides. A large national investment to train the next generation of CER researchers, as well as a commitment on the part of academic centers to prioritize CER training, is urgently needed. The Tufts CTSI is exquisitely well prepared to expand our role in training leaders and innovators in CER, to grow our core CER capacity, to help meet these critical needs. With this application, we aim to establish a Mentored Career Development Program in CER that builds on the breadth and depth of our research expertise across the full CER spectrum, as well as on our long history of training CER scholars and on our robust links to community and industry stakeholders. The purpose of this training program is: 1) to produce the leaders and innovators to help meet the nation's enormous CER challenges and workforce needs of the coming decade, and 2) (since CER is performed collaborative in teams) to further strengthen the Tufts CTSI as a Center of Excellence in CER. PUBLIC HEALTH RELEVANCE: Clinicians, patients, and payors need accurate and actionable information to make myriad important health care decisions every day. Yet often this information is unavailable. To provide this information, we need high quality comparative effectiveness research about the value of treatments. This application is to provide training for the next generation of leaders and innovators in comparative effectiveness research.