Tufts CTSI Career Development Program in Comparative Effectiveness Research

描述（由申请人提供）：自2008年成立以来，塔夫茨临床和转化研究所（CTSI）的主要目标是为有效开展比较有效性研究（CER）、开发创新CER方法以及培训CER研究员和学者开发全面的基础设施。基于这一领域的悠久传统，塔夫茨CTSI将一系列非凡的学科，新颖的方法和合作研究机会联系在一起，专注于“床边实践”和“实践到政策”的转化研究，并基于这些资产和这一重点，在协调国家CTSA联盟的反应方面发挥了领导作用。很明显，CER需要提供关于竞争性治疗方案的相对效益和成本的现成和可操作的信息，这远远超出了塔夫茨CTSI等学术研究中心的集体能力，国家的专业知识和CER能力主要集中在那里。迫切需要一个大的国家投资来培训下一代的CER研究人员，以及学术中心的承诺，以优先CER培训的一部分，是迫切需要的。塔夫茨CTSI已经做好了充分的准备，以扩大我们在培训CER领导者和创新者方面的作用，提高我们的核心CER能力，以帮助满足这些关键需求。有了这个应用程序，我们的目标是建立一个指导职业发展计划在CER，建立在我们的研究专业知识在整个CER频谱的广度和深度，以及我们的培训CER学者的悠久历史，并在我们强大的链接到社区和行业利益相关者。该培训计划的目的是：1）培养领导者和创新者，以帮助满足国家未来十年的巨大CER挑战和劳动力需求，2）（因为CER是在团队中合作进行的）进一步加强塔夫茨CTSI作为CER卓越中心。 公共卫生相关性：临床医生、患者和付款人每天都需要准确和可操作的信息来做出无数重要的医疗保健决策。然而，这些信息往往无法获得。为了提供这些信息，我们需要高质量的关于治疗价值的比较有效性研究。这个应用程序是为下一代的领导者和创新者在比较有效性研究提供培训。

DESCRIPTION (provided by applicant): From its inception in 2008, a major goal of the Tufts Clinical and Translational Institute (CTSI) has been to develop a comprehensive infrastructure for the efficient conduct of comparative effectiveness research (CER), the development of innovative CER methods, and the training of fellows and scholars in CER. Based on a long tradition in this area, the Tufts CTSI has linked an extraordinary array of disciplines, novel methods and collaborative research opportunities focused on "bedside-to-practice" and "practice-to-policy" translational research and, based on these assets and this focus, has played a leadership role in coordinating the response of the National CTSA Consortium. It has been clear that the need for CER to provide readily available and actionable information on the relative benefits and costs of competing treatment options far outstrips the collective capacity of academic research centers like the Tufts CTSI, where the nation's expertise and capacity for CER largely resides. A large national investment to train the next generation of CER researchers, as well as a commitment on the part of academic centers to prioritize CER training, is urgently needed. The Tufts CTSI is exquisitely well prepared to expand our role in training leaders and innovators in CER, to grow our core CER capacity, to help meet these critical needs. With this application, we aim to establish a Mentored Career Development Program in CER that builds on the breadth and depth of our research expertise across the full CER spectrum, as well as on our long history of training CER scholars and on our robust links to community and industry stakeholders. The purpose of this training program is: 1) to produce the leaders and innovators to help meet the nation's enormous CER challenges and workforce needs of the coming decade, and 2) (since CER is performed collaborative in teams) to further strengthen the Tufts CTSI as a Center of Excellence in CER. PUBLIC HEALTH RELEVANCE: Clinicians, patients, and payors need accurate and actionable information to make myriad important health care decisions every day. Yet often this information is unavailable. To provide this information, we need high quality comparative effectiveness research about the value of treatments. This application is to provide training for the next generation of leaders and innovators in comparative effectiveness research.