Collaborative Approach for Asian Americans and Pacific Islanders Research and Education (CARE) in Alzheimer’s Disease and Related Dementias.

项目摘要/CARE摘要 老年痴呆症是加州的第四大死因，而在美国则是第六大死因。 美国，以及患有阿尔茨海默病和相关痴呆症的美国人数量 预计到2050年，ADRD将从570万增加到1400万。必须确保 服务不足的社区，如亚裔美国人和太平洋岛民（AAPI）， 并接受过ADRD教育，因为AAPI和亚洲人对ADRD的了解存在差异。 美国照顾者在抑郁、负担和身体健康方面存在差异 与非西班牙裔白色照顾者相比，尽管AAPI增长最快， 有ADRD风险的美国老年人种族群体。AAPI的研究参与有限 稀疏的研究表明，AAPI有兴趣参与，但各种 需要解决关切问题（如缺乏文化/语言信息和不信任）， 提高ADRD研究的参与度，包括临床试验参与度。克服 这些障碍ADRD临床研究参与，我们将实施文化上适当的 和创新的招聘战略，从一个值得信赖的信息来源的协作团队 (e.g.社区合作伙伴）。拟议项目的最终目标，协作方法 亚裔美国人和太平洋岛民研究和教育（CARE） 阿尔茨海默氏病和相关痴呆症，是为了解决差距，减少差距， 通过建立一个登记册， 有兴趣参与各种类型的ADRD研究。护理将在五个 语言（英语、普通话、广东话、越南语、韩语），分布在加州的四个地点 (San弗朗西斯科湾区、萨克拉门托县、洛杉矶县和橙子县）。 CARE对于确保AAPI这一服务不足的人口被有意义地纳入 ADRD研究。援外社将完成以下工作：a）建立一个登记册， AAPI未来的ADRD研究; B）作为其他人群的招募模型; c） 提高AD中心/研究所的能力，并在 五所大学; d）制定一种强有力的方法，增加招聘科学， 在研究中保留少数群体，总体目标是减少ADRD差距。护理 涉及目标F.3。NIA老龄化研究的战略方向：“发展和 实施战略，使更多不同人群参与研究。"

Project Abstract/Summary of CARE Alzheimer's disease is the fourth leading cause of death in California compared to sixth in the U.S., and the number of Americans living with Alzheimer's Disease and Related Dementias (ADRD) is expected to increase from 5.7 to 14 million by 2050. It is important to ensure that underserved communities, such as Asian Americans and Pacific Islanders (AAPI), are engaged and educated on ADRD as disparities exist in knowledge about ADRD among AAPI and Asian American caregivers experience disparities in depression, burden, and physical health compared to non-Hispanic White caregivers even though AAPI are the most rapidly growing racial group of older Americans at risk for ADRD. Research participation from AAPI are limited and the sparse research suggests that AAPI are interested in being engaged, but that various concerns (e.g. lack of cultural/linguistic information and mistrust) need to be addressed in order to improve participation in ADRD research, including clinical trials participation. To overcome these barriers to ADRD clinical research participation, we will implement culturally appropriate and innovative recruitment strategies from a collaborative team of trusted sources of information (e.g. community partners). The ultimate goal of the proposed project, Collaborative Approach for Asian Americans and Pacific Islanders Research and Education (CARE) in Alzheimer's Disease and Related Dementias, is to address the gap and reduce disparities in ADRD research participation among AAPI through the creation of a registry of AAPI who are interested in participating in various types of ADRD research. CARE will be conducted in five languages (English, Mandarin, Cantonese, Vietnamese, Korean) across four sites in California (San Francisco Bay Area, Sacramento County, Los Angeles County, and Orange County). CARE is critical to ensure that AAPI, an underserved population, are meaningfully included in ADRD research. CARE will accomplish the following: a) Develop a registry that will facilitate future ADRD research with AAPI; b) Serve as a recruitment model for other populations; c) Increase the capacity of AD Centers/Institutes at and develop a new collaborative team across five universities; and, d) Develop a robust approach and add to the science of recruiting and retaining minorities in research with the overall goal of reducing ADRD disparities. CARE addresses Goal F.3. of NIA's Strategic Directions for Research on Aging: "develop and implement strategies to increase inclusion of diverse populations in research."