Collaborative Approach for Asian Americans and Pacific Islanders Research and Education (CARE) in Alzheimer’s Disease and Related Dementias.

CARE 项目摘要/摘要 阿尔茨海默病是加州第四大死亡原因，而在美国则排名第六 美国以及患有阿尔茨海默病和相关痴呆症的美国人数量 (ADRD) 预计到 2050 年将从 5.7 增加到 1400 万。重要的是要确保 亚裔美国人和太平洋岛民 (AAPI) 等服务不足的社区参与其中 并接受 ADRD 教育，因为亚太裔和亚洲人在 ADRD 知识方面存在差异 美国护理人员在抑郁、负担和身体健康方面存在差异 与非西班牙裔白人护理人员相比，尽管 AAPI 增长最快 美国老年人中存在 ADRD 风险的种族群体。 AAPI 的研究参与有限 稀疏的研究表明 AAPI 有兴趣参与其中，但不同的 需要解决关切问题（例如缺乏文化/语言信息和不信任），以便 提高 ADRD 研究的参与度，包括临床试验的参与度。克服 这些阻碍 ADRD 临床研究参与的障碍，我们将实施适合文化的措施 来自可信信息源协作团队的创新招聘策略 （例如社区合作伙伴）。拟议项目的最终目标，协作方法 亚裔美国人和太平洋岛民研究与教育 (CARE) 阿尔茨海默病和相关痴呆症，旨在解决差距并减少差异 通过创建 AAPI 登记册，AAPI 参与 ADRD 研究， 有兴趣参与各种类型的 ADRD 研究。 CARE 将在五 加利福尼亚州四个地点的语言（英语、普通话、粤语、越南语、韩语） （旧金山湾区、萨克拉门托县、洛杉矶县和奥兰治县）。 CARE 对于确保 AAPI（服务不足的人群）被有意义地纳入到社区中至关重要 ADRD 研究。 CARE 将实现以下目标： a) 开发一个登记处，以促进 未来与 AAPI 的 ADRD 研究； b) 作为其他人群的招募模型； c) 提高 AD 中心/机构的能力，并在各个领域建立新的协作团队 五所大学； d) 制定强有力的方法并增加招聘和培训的科学性 保留少数群体参与研究，总体目标是减少 ADRD 差异。关怀 解决目标 F.3。 NIA 老龄化研究战略方向：“发展和 实施战略以增加不同人群参与研究的程度。”

Project Abstract/Summary of CARE Alzheimer's disease is the fourth leading cause of death in California compared to sixth in the U.S., and the number of Americans living with Alzheimer's Disease and Related Dementias (ADRD) is expected to increase from 5.7 to 14 million by 2050. It is important to ensure that underserved communities, such as Asian Americans and Pacific Islanders (AAPI), are engaged and educated on ADRD as disparities exist in knowledge about ADRD among AAPI and Asian American caregivers experience disparities in depression, burden, and physical health compared to non-Hispanic White caregivers even though AAPI are the most rapidly growing racial group of older Americans at risk for ADRD. Research participation from AAPI are limited and the sparse research suggests that AAPI are interested in being engaged, but that various concerns (e.g. lack of cultural/linguistic information and mistrust) need to be addressed in order to improve participation in ADRD research, including clinical trials participation. To overcome these barriers to ADRD clinical research participation, we will implement culturally appropriate and innovative recruitment strategies from a collaborative team of trusted sources of information (e.g. community partners). The ultimate goal of the proposed project, Collaborative Approach for Asian Americans and Pacific Islanders Research and Education (CARE) in Alzheimer's Disease and Related Dementias, is to address the gap and reduce disparities in ADRD research participation among AAPI through the creation of a registry of AAPI who are interested in participating in various types of ADRD research. CARE will be conducted in five languages (English, Mandarin, Cantonese, Vietnamese, Korean) across four sites in California (San Francisco Bay Area, Sacramento County, Los Angeles County, and Orange County). CARE is critical to ensure that AAPI, an underserved population, are meaningfully included in ADRD research. CARE will accomplish the following: a) Develop a registry that will facilitate future ADRD research with AAPI; b) Serve as a recruitment model for other populations; c) Increase the capacity of AD Centers/Institutes at and develop a new collaborative team across five universities; and, d) Develop a robust approach and add to the science of recruiting and retaining minorities in research with the overall goal of reducing ADRD disparities. CARE addresses Goal F.3. of NIA's Strategic Directions for Research on Aging: "develop and implement strategies to increase inclusion of diverse populations in research."