Collaborative Approach for Asian Americans and Pacific Islanders Research and Education (CARE) in Alzheimer’s Disease and Related Dementias.

项目摘要/服务摘要 阿尔茨海默病是加利福尼亚州的第四大死因，而在美国是第六大死因 美国，以及患有阿尔茨海默病和相关痴呆的美国人的数量 预计到2050年，美国国内生产总值(ADRD)将从570万增加到1400万。重要的是确保 服务不足的社区，如亚裔美国人和太平洋岛民(AAPI)，正在参与 并接受有关ADRD的教育，因为AAPI和亚洲人对ADRD的了解存在差异 美国照顾者在抑郁、负担和身体健康方面存在差异 与非西班牙裔白人照顾者相比，尽管AAPI增长最快 老年美国人中有患ADRD风险的种族群体。来自AAPI的研究参与有限 这项稀少的研究表明，AAPI有兴趣参与，但不同的 需要按顺序解决关切问题(例如，缺乏文化/语言信息和不信任) 提高ADRD研究的参与度，包括临床试验的参与度。要克服 这些障碍阻碍了ADRD临床研究的参与，我们将在文化上适当地实施 以及来自可信信息来源协作团队的创新招聘策略 (例如社区合作伙伴)。拟议项目的最终目标是协作方法 针对亚裔美国人和太平洋岛民的研究和教育(CARE) 阿尔茨海默病和相关痴呆症，是为了解决这一差距，减少 通过建立AAPI的登记册，在AAPI中参与ADRD研究，这些人 有兴趣参与各种类型的ADRD研究。护理将在五年内进行 加州四个站点的语言(英语、普通话、广东话、越南语、韩语) (旧金山湾区、萨克拉门托县、洛杉矶县和奥兰治县)。 护理对于确保AAPI这一服务不足的人口有意义地包括在 ADRD研究。CARE将实现以下目标：a)建立一个登记处，以便 与AAPI进行的未来ADRD研究；b)作为其他人口的招募模式；c) 增加AD中心/研究所的能力，并建立一个新的协作团队 五所大学；以及，d)制定一种强有力的办法，增加招聘和 在研究中保留少数群体，总体目标是减少ADRD差异。关怀 解决目标F.3。NIA老龄化研究的战略方向：“发展和 实施战略，增加不同人群参与研究的机会。“

Project Abstract/Summary of CARE Alzheimer's disease is the fourth leading cause of death in California compared to sixth in the U.S., and the number of Americans living with Alzheimer's Disease and Related Dementias (ADRD) is expected to increase from 5.7 to 14 million by 2050. It is important to ensure that underserved communities, such as Asian Americans and Pacific Islanders (AAPI), are engaged and educated on ADRD as disparities exist in knowledge about ADRD among AAPI and Asian American caregivers experience disparities in depression, burden, and physical health compared to non-Hispanic White caregivers even though AAPI are the most rapidly growing racial group of older Americans at risk for ADRD. Research participation from AAPI are limited and the sparse research suggests that AAPI are interested in being engaged, but that various concerns (e.g. lack of cultural/linguistic information and mistrust) need to be addressed in order to improve participation in ADRD research, including clinical trials participation. To overcome these barriers to ADRD clinical research participation, we will implement culturally appropriate and innovative recruitment strategies from a collaborative team of trusted sources of information (e.g. community partners). The ultimate goal of the proposed project, Collaborative Approach for Asian Americans and Pacific Islanders Research and Education (CARE) in Alzheimer's Disease and Related Dementias, is to address the gap and reduce disparities in ADRD research participation among AAPI through the creation of a registry of AAPI who are interested in participating in various types of ADRD research. CARE will be conducted in five languages (English, Mandarin, Cantonese, Vietnamese, Korean) across four sites in California (San Francisco Bay Area, Sacramento County, Los Angeles County, and Orange County). CARE is critical to ensure that AAPI, an underserved population, are meaningfully included in ADRD research. CARE will accomplish the following: a) Develop a registry that will facilitate future ADRD research with AAPI; b) Serve as a recruitment model for other populations; c) Increase the capacity of AD Centers/Institutes at and develop a new collaborative team across five universities; and, d) Develop a robust approach and add to the science of recruiting and retaining minorities in research with the overall goal of reducing ADRD disparities. CARE addresses Goal F.3. of NIA's Strategic Directions for Research on Aging: "develop and implement strategies to increase inclusion of diverse populations in research."