GEROSCIENCE TRAINING PROGRAM IN OKLAHOMA

俄克拉荷马州老年科学培训计划

• 批准号: 10163757
• 负责人: William Edmund Sonntag
• 金额: $ 40.75万
• 依托单位: UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-05-01 至 2022-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10163757
• 关键词: Geroscience; Oklahoma; Training Programs

ABSTRACT This application is a revision of an application requesting 5 years of funding for an interdisciplinary training on the biology of aging for 3 pre-doctoral students and 4 post-doctoral fellows. The proposed program builds on the rapidly expanding expertise of 7 academic/research programs and three (3) institutions, University of Oklahoma Health Sciences Center (OUHSC), Oklahoma Medical Research Foundation (OMRF) and the Oklahoma City VA Medical Center. With the increased number of older individuals in the United States and the world, the proposed program has been created to address the unprecedented demand for researchers with expertise in the biology of aging that are trained to address the complex nature of research on aging and age-related diseases. OUHSC, OMRF and the VA have devoted extensive resources to the development of aging programs and in the past 7 years, and researchers from these programs have been awarded over $83M in research/infrastructure support and published over 200 peer-reviewed manuscripts. This investment resulted in the recent successful submission of a Nathan Shock Center of Excellence that was funded in July 2015. The primary goal of this program is to prepare graduate students and post-doctoral fellows for careers as leaders in the emerging field of Geroscience. Our goal is to provide rigorous, outstanding, innovative training for future scientists that are entering specific disciplines in aging research. The program is composed of 15 faculty members from the OUHSC/OMRF/VA campus and captures the intense collaborations, enthusiasm and the unique resources of the aging community. The program is also supported by exceptional commitment from OUHSC and OMRF, the Donald W. Reynolds Foundation and numerous programs and cores that are continuously supported by each institution. Trainees selected for this program will be chosen competitively based on academic excellence and their interest and motivation for careers in aging research. The primary activity of the trainees will be to develop and complete research projects relevant to aging and/or age-related disease using state-of-the-art technologies in genomics, proteomics, epigenetics, cell biology, biochemistry and physiology. Because of the close collaborations among our faculty, trainees will be required to have a primary and secondary mentor to ensure the highest quality of training and focus on aging research. The trainees will also benefit from our Geroscience courses, clinical experiences, seminar programs, journal clubs and retreats that are taught/overseen by well-established leaders in the field of aging. Finally trainees will be mentored to develop appropriate presentation and grant writing skills and will be required to submit an independent F-series grant proposal. In summary, this training program is designed to help exceptional young scientists develop the intellectual, technical, writing and presentation skills needed for productive careers as independent investigators and educators in aging research. !

抽象的 此申请是对申请的修订，要求为跨学科提供5年资金 培训3名博士后学生和4名博士后研究员的衰老生物学培训。提议 计划以7个学术/研究计划的迅速扩展的专业知识和3（3）为基础 俄克拉荷马大学健康科学中心（OUHSC）机构，俄克拉荷马州医学研究 基金会（OMRF）和俄克拉荷马城弗吉尼亚州医疗中心。随着年龄较大的数量增加 在美国和世界上，已经创建了拟议的计划来解决 对具有衰老生物学专业知识的研究人员的前所未有的需求，他们经过培训以解决 关于衰老和年龄相关疾病的研究的复杂性质。 OUHSC，OMRF和VA专门 在过去的7年中，大量的资源用于发展衰老计划，以及 这些计划已获得超过8300万美元的研究/基础设施支持，并发布了200多个 同行评审的手稿。这项投资导致了Nathan最近成功提交的 2015年7月资助的卓越冲击中心。该计划的主要目标是准备 作为新兴领域的领导者，研究生和博士后研究员 Geroscience。我们的目标是为未来的科学家提供严格，杰出，创新的培训 进入衰老研究中的特定学科。该计划由来自 OUHSC/OMRF/VA校园，并捕捉了激烈的合作，热情和独特的资源 衰老社区。该计划还得到了OUHSC的杰出承诺和 OMRF，Donald W. Reynolds基金会以及许多不断的计划和核心 得到每个机构的支持。为此计划选择的学员将根据 学术卓越及其对衰老研究的职业的兴趣和动力。主要活动的主要活动 学员将开发和完成与衰老和/或与年龄有关的疾病有关的研究项目 在基因组学，蛋白质组学，表观遗传学，细胞生物学，生物化学和 生理。由于我们教师之间的密切合作，学员将被要求 初级和次要导师，以确保最高质量的培训并专注于衰老研究。这 学员还将受益于我们的Geroscience课程，临床经验，研讨会计划，杂志 由衰老领域良好的领导人教/监督的俱乐部和务虚会。终于学员 将受到指导以制定适当的演讲和授予写作技巧，并需要提交 独立的F系列赠款提案。总而言之，该培训计划旨在帮助杰出 年轻的科学家发展了生产力所需的智力，技术，写作和演讲技巧 职业是衰老研究的独立研究人员和教育者。 呢