Accelerating Excellence in Translational Science (AXIS)

加速转化科学的卓越发展 (AXIS)

• 批准号: 10173019
• 负责人: Jaydutt V. Vadgama
• 金额: $ 19.2万
• 依托单位: CHARLES R. DREW UNIVERSITY OF MED & SCI
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-28 至 2024-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10173019
• 关键词: AIDS/HIV problem; Affect; African American; Area; Behavioral; Bioinformatics; Cardiovascular Diseases; Center for Translational Science Activities; Chronic; Clinical; Clinical Research; Collaborations; Communicable Diseases; Communities; Community Services; County; Development; Diabetes Mellitus; Diagnosis; Discipline; Disease; Environmental Risk Factor; Epigenetic Process; Fostering; Goals; Health; Health Services; Hispanics; Hypertension; Incidence; Infrastructure; Institution; Intervention; Latino; Leadership; Location; Los Angeles; Malignant Neoplasms; Medical; Medicine; Mental Health; Mental Health Services; Mentors; Mission; Modeling; Molecular Genetics; Morbidity - disease rate; Obesity; Outcome; Pathway interactions; Research; Research Personnel; Research Training; Resources; Schools; Science; Services; Statistical Methods; Statistical Study; Strategic Planning; Technology; Tissues; Training and Education; Translating; Translational Research; Universities; Vision; biobank; cardiometabolism; care systems; clinical care; demographics; drug discovery; epidemiology study; experience; genomic data; health care availability; health disparity; minority health; mortality; next generation sequencing; precision medicine; programs; public health relevance; racial and ethnic; socioeconomics; success; treatment services

Abstract: Proposed Program Overview. The Charles R. Drew University of Medicine and Science proposes to continue the enhancement and success of the Accelerating Excellence in Translational Science (AXIS) Center. AXIS has shown to be the integrated hub for research conducted at CDU and continues to provide experienced leadership, and a myriad of clinical, translational, and community partnered activities. In the next five years, research will continue to grow and expand its enterprise alongside the Universities vision and mission to be a leader in eliminating health disparities by translating scientific discoveries into education, training, clinical care, treatment, and community service in three areas of focus which disproportionally affect Service Planning Area 6: Cancer, Cardiometabolic Disease (CMD), and HIV/AIDS. In addition, we look to build upon the application of Precision Medicine to understand and eliminate health disparities, while utilizing many of CDU’s outstanding resources in: Advanced Technologies such as Next Generation Sequencing for identifying Genomic Data; Drug Discovery; Integrated Clinical Tissues, Biorepository and Bio banking Facility; Clinical Studies/Trials Resources; Medical Bioinformatics; and Methods for Statistical and Epidemiological Studies. This approach will pave the pathway for CDU’s in becoming a competitive institution with sophisticated resources and services to better serve our communities. To accomplish this, we propose to continue with the three programmatic goals that align with the mission, vision, and strategic plan for the universities research enterprise: Goal 1: To enhance the infrastructure capacity in translational research using Precision Medicine model in the areas of Cancer, Cardiometabolic, and HIV/AIDS. Provide support for the emerging research pillars in Mental Health and Health Services Goal 2: To continue the integration of basic, clinical, behavioral and community-partnered research by fostering collaboration among disciplines, departments and schools at CDU, and sustainable collaboration with community leaders and investigators across other research institutions. Goal 3: To facilitate and elevate professional development and best practices in mentored clinical and translational research training on minority health and health disparities.

摘要：拟建项目概述。查尔斯R.德鲁医学与科学大学提出