Leveraging Unique Capabilities and Capacities for Chemical Analyses of Diverse Food and Feed Matrices in Support of an Integrated Food Safety System

总括 项目摘要 加州动物健康和食品安全实验室系统(CAHFS)是加利福尼亚州的州兽医 诊断实验室，负责确保国家农业动物的健康和动物的安全 动物性食品。CAHFS毒物科作为一个经验丰富的 和设备齐全的兽医毒理实验室，是FDA在 促进他们保护美国食品和动物饲料免受不安全化学物质伤害的使命 污染。 卫生与公众服务部提议，通过参加《 福阿。首先，CAHFS毒物科将为该机构提供重大的增援能力 涉及故意或意外造成人体化学污染的紧急事件 食物或动物饲料。该科过去在处理与粮食有关的紧急情况方面的业绩 展示了它在这些情况下的用处。 在需要新的分析能力和能力的地方，毒物科将开发新的 方法，参与多实验室方法验证，评估新的分析平台，并努力 应要求以创造性和坚韧不拔的精神解决新出现的食品和饲料安全问题。这些 活动对于帮助该机构解决令人担忧的新化学品和采用更多 灵敏和选择性的检测能力。对新的分析平台的评估有助于该机构 确定更有效的分析方法，以扩大分析能力。 此外，CAHFS将对加州生产的牲畜饲料进行监测分析。CAHFS是 寻求用于采样和分析的资金。毒物科将与 加州食品和农业部(CDFA)，这是负责监管的州机构 动物饲料。国家食品药品监督管理局将按照FDA的规范提供样品给实验室进行分析。 涉及不符合监管要求的样本的测试结果将报告给 FDA和CDFA。CAHFS明白，这一筹资机会涉及大量合作 与CDFA监管机构合作，成为提供样本的合作伙伴。通过建立这种类型的合作 并对这些样本进行测试，该科将能够协助该机构迅速查明新出现的 污染问题，防止接触受污染的食物或饲料，最终防止伤害 为了人类和动物的健康。

Overall Project Summary The California Animal Health and Food Safety Laboratory System (CAHFS) is California’s state veterinary diagnostic laboratory, responsible for assuring the health of the state’s agricultural animals and safety of foods of animal origin. The CAHFS Toxicology Section occupies a unique position as a highly experienced and well-equipped veterinary toxicology laboratory and is a natural fit as a partner to the FDA in furthering their mission of protecting food and animal feed in the U.S. from unsafe chemical contamination. CAHFS proposes to assist the agency through participation in several key activities as outlined in the FOA. First, the CAHFS Toxicology Section will provide significant surge capacity to the agency in the event of an emergency incident involving intentional or accidental chemical contamination of human food or animal feed. The Section’s past performance in addressing food-related emergencies demonstrates its usefulness in these situations. Where new analytical capabilities and capacity are needed, the Toxicology Section will develop new methods, participate in multi-lab method validations, evaluate new analytical platforms, and endeavor to address emerging food and feed safety issues with creativity and tenacity as requested. These activities are critical in helping the agency address new chemicals of concern and in adopting more sensitive and selective detection capabilities. Evaluation of new analytical platforms assists the agency in identifying more efficient methods of analysis, allowing for expanded analytical capacity. Additionally, CAHFS will perform surveillance analysis of livestock feeds produced in California. CAHFS is seeking funding for both sampling and analysis. The Toxicology Section will work in partnership with the California Department of Food and Agriculture (CDFA), which is the state agency in charge of regulating animal feed. CDFA will provide samples taken as per FDA specifications to the laboratory for analysis. Test results involving samples which do not meet regulatory requirements will be reported to both the FDA and to CDFA. CAHFS understands that this funding opportunity involves a great deal of cooperation with CDFA regulators as they become partners in providing samples. By building this type of cooperation and testing these samples, the Section will be able to assist the agency in quickly identifying emerging contamination issues, preventing exposures to contaminated food or feed, ultimately preventing injury to human and animal health.