Ophthalmic Therapeutics Engineering Core
Ophthalmic Therapeutics Engineering Core
批准号:
10178034
负责人:
John Andrew MacKay
金额:
$16.65万
依托单位国家:
美国
项目类别:
财政年份:
2018
资助国家:
美国
项目状态:
已结题
起止时间:
2018-09-30 至 2023-05-31
关键词:
AnteriorBasic ScienceBiologicalCellular biologyCenter Core GrantsChemicalsComputers and Advanced InstrumentationConsultationsCoupledCustomDevelopmentDevicesDiseaseDrug Delivery SystemsDrug TargetingEngineeringExperimental DesignsEyeFormulationMechanicsMolecularOcular PhysiologyPharmaceutical PreparationsPlayProceduresResearchResearch PersonnelResearch Project GrantsResourcesRoleServicesSiteStructureTechnical ExpertiseTechniquesTechnologyTherapeuticUltrasonographyVision researchdesigndesign and constructionelastographyimprovedinnovationinnovative technologiesinstrumentinstrumentationinvestigator trainingmechanical devicenanoassemblynanomedicinenovelnovel therapeutic interventionnovel therapeuticsoperationprogramstargeted deliverytechnology research and developmenttranslational scientistvision science
中文摘要
项目总结-眼科治疗工程核心
眼科治疗工程核心将提供必要的资源,以促进平移视觉
科学和技术研究,以开发新的眼科疾病治疗方法。核心将支持
表征分子纳米结构所需的分子工程仪器和技术专长,
设计用于携带药物的组件,加上针对其靶向递送的设备工程专业知识,
直接的治疗应用。共享和集中资源的可用性加快了
开发新的治疗方法,以高效和有效地将治疗精确地提供给特定的
网站的眼睛,使用创新技术。核心的综合资源将发挥重要作用
在基础科学、工程学和转化视觉研究之间建立桥梁,以开发新的眼部治疗方法。
接近。具体目标是提供仪器和技术专长:1)开发,
表征和优化生物、化学或机械药物递送系统; 2)设计和
制造定制的设备和仪器,可以改善或推进实验程序,
研究者的研究能力,特别是那些涉及提供治疗的研究者; 3)培训
研究人员研究可用仪器的实用性和操作,以设计和表征
治疗药物递送载体和装置;和4)关于实验设计的咨询,
具体技术的适当性,以及工程技术的集成,以逐步提高进度
视觉研究项目。
英文摘要
Project Summary – Ophthalmic Therapeutics Engineering Core
The Ophthalmic Therapeutics Engineering Core will provide essential resources to facilitate translational vision
science and technology research for development of new therapies for ocular diseases. The Core will support
instrumentation and technical expertise in molecular engineering required to characterize molecular nano-
assemblies designed to carry drugs coupled with expertise in device engineering for their targeted delivery or
direct therapeutic applications. The availability of shared and centralized resources accelerates the
development of new therapeutic approaches to efficiently and effectively deliver therapies precisely to specific
sites in the eye, using innovative technologies. The integrated resources of the Core will play an essential role
in bridging basic science, engineering, and translational vision research for developing novel ocular therapeutic
approaches. The specific aims are to provide instrumentation and technical expertise for: 1) developing,
characterizing and optimizing biological, chemical, or mechanical drug delivery systems; 2) designing and
fabricating custom devices and instruments that can improve or advance experimental procedures and
research capabilities of investigators, particularly those involving delivery of therapeutics; 3) training
investigators on the utility and operation of available instrumentation for the design and characterization of
therapeutic drug delivery vehicles and devices; and 4) consultations on the experimental design,
appropriateness of the specific techniques, and integration of engineering techniques to escalate the progress
of vision research projects.
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会议论文
Ophthalmic Therapeutics Engineering Core
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批准号:10413121
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项目类别:
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资助金额:$16.65万
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财政年份:2018
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负责人:John Andrew MacKay
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依托单位:
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项目类别:
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依托单位:
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批准号:7978859
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项目类别:
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资助金额:$24.3万
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依托单位:
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项目类别:
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资助金额:$19.46万
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财政年份:2010
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依托单位:
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批准号:7156669
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项目类别:
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资助金额:$4.6万
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财政年份:2006
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负责人:John Andrew MacKay
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依托单位:
pH sensitive elastin-like-peptides for tumor targeting
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批准号:7262427
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项目类别:
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资助金额:$4.88万
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财政年份:2006
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负责人:John Andrew MacKay
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依托单位:
Ophthalmic Therapeutics Engineering Core
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批准号:9788482
-
项目类别:
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资助金额:$16.65万
-
财政年份:--
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负责人:John Andrew MacKay
-
依托单位:
海外基金