UAB Training Program In Neuroscience

UAB 神经科学培训项目

• 批准号: 10197228
• 负责人: DAVID G. STANDAERT
• 金额: $ 15.01万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-01 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10197228
• 关键词: Neurosciences; Training Programs

Abstract This is a proposal for a new T32 training program at the University of Alabama at Birmingham (UAB). This is a focused program for predoctoral students in basic and translational approaches to neurodegenerative disease. The rationale for establishing this new program is founded on three critical factors: 1) The aging of the US population, which will soon lead to growth in the numbers of patients affected by neurodegenerative disease, 2) Rapid advances in tools and technologies in the neurosciences, and 3) The increasing interest in neurosciences as a discipline by PhD students. A primary goal of this Training Program is to achieve cross- cultural training; we seek to expose students to the biological mechanisms and research approaches used across neurodegenerative disease, rather than the kind of single-disease training they might get working in an individual research laboratory. This program will provide support for advanced pre-doctoral students in the research phase of their training. Most students will enter the Neurodegeneration Training Program from the UAB Graduate Biomedical Science Program, which admits about 80 students annually, or the UAB Medical Scientist Training Program, which admits 8 students annually. Planned duration of appointment to the training program is two years for each student. A total of 2 slots are requested in Year 1, and 4 slots in subsequent years. Students will work under the supervision of one of 24 highly qualified mentors. Three of these are junior mentors, and there are plans for mentor development and co-mentoring. The program incorporates required didactic course work in neurodegeneration in both the first and second years, a newly developed formal course in experimental rigor, training in new tools and technologies, instruction in the translational pathway and drug development, a journal club on Neurodegeneration, an annual retreat, and mentor and outcomes evaluations. Our core philosophy is that we seek to enable the cures of the future by providing a robust training pathway in translational research. This unique emphasis will enable our students to take leading roles in therapeutic discovery across the spectrum of different skills sets and enterprises which are required to deliver the vitally needed treatments of the future.

摘要 这是阿拉巴马大学伯明翰分校(UAB)一项新的T32培训计划的提案。这是一个 面向神经退行性疾病的基本和翻译方法的博士前学生的重点课程。 建立这一新计划的理由基于三个关键因素：1)美国的老龄化 这将很快导致神经退行性疾病患者数量的增长， 2)神经科学工具和技术的快速发展，以及3)对 神经科学作为一门学科被博士生选中。这一培训计划的一个主要目标是实现交叉 文化培训；我们试图让学生接触到所使用的生物机制和研究方法 跨越神经退行性疾病，而不是他们可能在 单独的研究实验室。该计划将为高级博士后研究生提供支持 他们训练的研究阶段。大多数学生将参加神经变性培训计划 每年招收约80名学生的UAB生物医学研究生项目，或UAB医学 科学家培训计划，每年招收8名学生。培训的计划聘用期 每名学生的课程是两年。第1年共申请2个插槽，后续申请4个插槽 好几年了。学生将在24名高素质导师的指导下工作。其中三个是初级的 导师，还有导师发展和共同导师的计划。该计划包含所需的 一年级和二年级神经变性的教学课程，这是一门新开发的正式课程 严谨的实验，新工具和新技术的培训，翻译途径和药物的指导 发展，一个关于神经退行性变的期刊俱乐部，年度静修，以及导师和结果评估。 我们的核心理念是，我们寻求通过在以下方面提供强大的培训途径来实现未来的治疗 翻译研究。这一独特的强调将使我们的学生能够在治疗中发挥主导作用 跨不同技能组合和企业的发现，这些技能和企业需要提供至关重要的 未来需要的治疗方法。