UAB Training Program In Neuroscience

UAB 神经科学培训项目

• 批准号: 10197228
• 负责人: DAVID G. STANDAERT
• 金额: $ 15.01万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-01 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10197228
• 关键词: Neurosciences; Training Programs

Abstract This is a proposal for a new T32 training program at the University of Alabama at Birmingham (UAB). This is a focused program for predoctoral students in basic and translational approaches to neurodegenerative disease. The rationale for establishing this new program is founded on three critical factors: 1) The aging of the US population, which will soon lead to growth in the numbers of patients affected by neurodegenerative disease, 2) Rapid advances in tools and technologies in the neurosciences, and 3) The increasing interest in neurosciences as a discipline by PhD students. A primary goal of this Training Program is to achieve cross- cultural training; we seek to expose students to the biological mechanisms and research approaches used across neurodegenerative disease, rather than the kind of single-disease training they might get working in an individual research laboratory. This program will provide support for advanced pre-doctoral students in the research phase of their training. Most students will enter the Neurodegeneration Training Program from the UAB Graduate Biomedical Science Program, which admits about 80 students annually, or the UAB Medical Scientist Training Program, which admits 8 students annually. Planned duration of appointment to the training program is two years for each student. A total of 2 slots are requested in Year 1, and 4 slots in subsequent years. Students will work under the supervision of one of 24 highly qualified mentors. Three of these are junior mentors, and there are plans for mentor development and co-mentoring. The program incorporates required didactic course work in neurodegeneration in both the first and second years, a newly developed formal course in experimental rigor, training in new tools and technologies, instruction in the translational pathway and drug development, a journal club on Neurodegeneration, an annual retreat, and mentor and outcomes evaluations. Our core philosophy is that we seek to enable the cures of the future by providing a robust training pathway in translational research. This unique emphasis will enable our students to take leading roles in therapeutic discovery across the spectrum of different skills sets and enterprises which are required to deliver the vitally needed treatments of the future.

抽象的 这是阿拉巴马大学伯明翰分校 (UAB) 的新 T32 培训计划的提案。这是一个 针对博士前学生的神经退行性疾病基础和转化方法的重点项目。 建立这一新计划的理由基于三个关键因素：1）美国的老龄化 人口，这将很快导致受神经退行性疾病影响的患者数量增加， 2) 神经科学工具和技术的快速进步，以及 3) 人们对神经科学的兴趣日益浓厚 神经科学作为博士生的一门学科。该培训计划的主要目标是实现跨 文化培训；我们致力于让学生了解所使用的生物机制和研究方法 跨越神经退行性疾病，而不是他们可能在一个单一的疾病培训中工作 个人研究实验室。该计划将为高级博士前学生提供支持 他们的培训的研究阶段。大多数学生将从 UAB 研究生生物医学科学项目，每年招收约 80 名学生，或 UAB 医学 科学家培训计划，每年招收 8 名学生。计划的培训预约持续时间 每个学生的课程为期两年。第一年总共请求 2 个名额，随后的 4 个名额 年。学生将在 24 名高素质导师之一的监督下工作。其中三个是小学生 导师，并有导师发展和共同指导的计划。该计划包含所需的 第一年和第二年的神经退行性疾病教学课程，这是一门新开发的正式课程 实验严谨性、新工具和技术培训、转化途径和药物指导 发展、神经退行性疾病期刊俱乐部、年度静修会以及导师和成果评估。 我们的核心理念是，我们寻求通过提供强大的培训途径来实现未来的治疗方法 转化研究。这种独特的重点将使我们的学生能够在治疗领域发挥主导作用 发现交付重要产品所需的不同技能组合和企业 未来需要的治疗方法。