The AnVIL Data Ecosystem

项目摘要 在努力实现砧板的长期目标中，提供一个统一的摄取和 组织大量当前和未来的基因组和与基因组相关的数据集，显然 实现多个平台和数据集的串扰是一个关键障碍。为了克服这一挑战，我们 提议在Terra平台内改进、采用和实施DRS和RAS的共享标准。去做 为此，我们提出以下目标和分目标： 1.通过制定和实施以下方面的标准，加强跨系统互操作性 身份验证并用于共享数据和应用程序 1.1互操作性标准和技术要求：完善互操作性标准、范围 支持这些标准所需的技术工作，并开发跨系统的约定 促进这些用例的实现 1.2 Terra DRS和RAS支持： 确保GA4GH DRS1.1支持。数据应可通过支持以下内容的协议访问 互操作性用例中描述的系统。DRS 1.1是最新版本的 GA4GH标准，包括GUID支持 包括RAS帐户链接和令牌管理 确保随着约定的完善，全氟辛酸搜索切换支持改进 确保莱昂纳多支持DRS1.1和RAS 1.3 Galaxy和R/BioConductor DRS和RAS支持： 确保在Galaxy和R/BioConductor中支持GA4GH DRS1.1，以便可以访问数据 使用该标准 包括与Terra中的Galaxy和RStudio实例共享RAS令牌，允许Galaxy和 R/BioConductor使用RAS凭据访问DRS可访问的数据 2.完成将RAS支助纳入数据使用监督系统(DOS)所需的范围 2.1完成作用域划分，以增加对DUO的支持，使数据访问委员会能够向 研究人员

Project Summary In working to achieve the long-term goal of the AnVIL of providing a unified platform for ingestion and organization for a multitude of current and future genomic and genome-related datasets, it is clear that enabling the cross-talk of multiple platforms and datasets is a critical barrier. To overcome this challenge, we propose to improve, adopt, and implement shared standards for DRS and RAS within the Terra platform. To do that, we propose the following aims and subaims: 1. Enhance cross-system interoperability through development and implementation of standards for authentication and for sharing data and applications 1.1 Interoperability standards and technical requirements: Improve interoperability standards, scope technical work needed to support these standards, and develop conventions across systems to facilitate the realization of these use cases 1.2 Terra DRS and RAS support:  Ensure GA4GH DRS 1.1 support. Data should be accessible over the protocol supporting the systems described in the interoperability use cases. DRS 1.1 is the latest version of the GA4GH standard and includes GUID support  Include RAS account linking and token management  Ensure PFB search handoff support improvements as the convention is refined  Ensure Leonardo accommodates DRS 1.1 and RAS support 1.3 Galaxy and R / Bioconductor DRS and RAS support:  Ensure GA4GH DRS 1.1 support in Galaxy and R / Bioconductor, so data can be accessed using that standard  Include RAS token sharing with Galaxy and RStudio instances in Terra, allowing Galaxy and R / Bioconductor to access DRS accessible data using RAS credentials 2. Complete the scoping required to integrate RAS support into the Data Use Oversight System (DUOS) 2.1 Complete scoping to add support to DUOS to enable data access committees to issue visas to researchers