Gabriella Miller Kids First Pediatric Data Resource Center: Advancing Collaborative Platform-Enabled Data-Driven Discovery at the Intersection of Childhood Development and Cancer

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PROJECT SUMMARY Since its launch, the Gabriella Miller Kids First Data Resource Center (KFDRC) has constantly innovated and helped redefine the architecture, development and operations across all cores of work to optimize and provide opportunities for the research community to have impact in childhood cancer and structural birth defects. This has included collaborative partnerships across the NIH data commons landscape to ensure the FAIRness of Kids First data and enable rapid access of data in cloud-based platforms. In the next phase, the KFDRC will build on these innovations and successes to further empower sustained, scaled growth and impact. This will be a cross-coordinated effort across the Administrative and Outreach Core, the Data Coordinating Core and the Data Resource Core. The combined efforts of these cores will provide researchers the data, tools, and workspaces they need to further the mission of the Kids First program. The KFDRC will make significant contributions to accelerate community efforts not only to understand etiology and drivers of pediatric diseases, but also drive and enhance the interpretation and clinical decision support for better outcomes for children.