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中文摘要
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项目摘要 AnVIL环境使用领先的云规模网络基础设施作为基础, NHGRI研究人员审查的广泛使用的分析环境和框架。本项目的总体目标 ODSS补充提案旨在增强用户体验,提高互操作性、数据访问和 共享和数据可见性。为了实现这些目标,我们提出了七个目标,每个目标都涉及到以下几个方面: 数据访问、可共享性和可见性。综合起来,所有目标将显著改善用户体验 在Anvil。目标1。FHIR的工作:为了应对跨部门搜索和交换数据的挑战, 我们正在扩大与FHIR的合作,包括创建AnVIL FHIR应用程序, 支持FHIR的单用户租户,让用户轻松地将EMR数据加载到AnVIL中。目标2.地球作为一个 GA4GH护照经纪人:为了现代化和扩展数据访问权限,AnVIL将利用 RAS的功能和标准化。此外,使Terra成为GA4GH护照经纪人,我们将联合收割机访问 通过白名单、dbGaP授权和其他passport代理进行控制,以极大地改善数据访问 控制目标3。Terra支持DRS 1.x作为服务器:努力提高AnVIL的板载能力 并在其他合作伙伴中使用数据,我们将继续在Terra中扩展DRS支持。这项工作使AnVIL 在更大的可信赖合作伙伴生态系统中。目标4。NCPI门户网站和数据集索引:扩展数据 可见性,NCPI数据集目录将建立一个自动化机制,直接与平台接口 允许查询和检索研究信息及相关元数据的API。直接访问 平台的FHIR服务器将减少人工工作,从而提高数据的质量和及时性。 目标5。跨平台的“应用程序”标准化:简化复杂应用程序的部署, AnVIL因此走向一个全面的平台,AnVIL将扩展在 具有Kubernetes支持的BioData Catalyst可显著提高AnVIL的灵活性和可扩展性 平台目标6。FHIR代码库:努力吸引NCPI平台和科学界成员 在开发利用FHIR表示的研究数据和API的工具时,我们将托管一系列虚拟 FHIR编码马拉松目标7。NIH DUOS试点扩展:为了应对可扩展性挑战,AnVIL将 将DUOS试点计划扩展到五个新的群体,使我们能够收集有关DUOS的定性信息 试点扩展,将促进数据访问委员会使用和采用DUOS。
英文摘要
Project Summary The AnVIL environment uses leading cloud-scale cyberinfrastructure as the foundation supporting the most widely-used analysis environments and frameworks vetted by NHGRI researchers. The overall goals of this ODSS supplement proposal are to enhance the user experience and increase interoperability, data access and sharing, and data visibility. To accomplish these objectives, we propose seven aims, each tackling components of data access, shareability, and visibility. In combination, all aims will significantly improve the user experience in AnVIL. Aim 1. FHIR work: In order to address challenges in searching and exchanging data across biomedical research systems, we are expanding work with FHIR to include creating an AnVIL FHIR app and stand up single user tenants for FHIR for users to easily load their EMR data into AnVIL. Aim 2. Terra as a GA4GH Passport Broker: To modernize and expand data access permissions, the AnVIL will harness the power and standardization of RAS. Further, enabling Terra as a GA4GH passport broker, we combine access control through whitelists, dbGaP authorizations, and other passport brokers to greatly improve data access control. Aim 3. Terra supporting DRS 1.x as a server: In an effort to improve AnVIL’s capacity to onboard and use data within other partners, we will continue expansion of DRS support in Terra. This work aligns AnVIL in the larger ecosystem of trusted partners. Aim 4. NCPI Portal and Dataset indexing: To expand data visibility, the NCPI Dataset Catalog will build an automated mechanism to interface directly with the platform APIs to allow querying and to retrieve the study information and associated metadata. Direct access to the platform's FHIR server will reduce the manual effort and hence improve the quality and timeliness of the data. Aim 5. Standardization of "apps" across Platforms: To ease deployment of complex applications within AnVIL thereby moving toward a comprehensive platform, AnVIL will extend the app standardization created in BioData Catalyst with the Kubernetes support to dramatically increase flexibility and extensibility of the AnVIL platform. Aim 6. FHIR Codeathon: In an effort to engage NCPI platforms and scientific community members in developing tools that leverage FHIR-represented research data and APIs, we will host a series of Virtuaal FHIR Code-a-thons. Aim 7. NIH DUOS Pilot Expansion: To address scalability challenges, the AnVIL will extend the DUOS pilot program to five new groups allowing us to pull together qualitative information on DUOS pilot expansion that will promote the use and adoption of DUOS by Data Access Committees.
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AnVIL Clinical Environment for Innovation and Translation (ACE-IT)
Data Management and Portal for the INCLUDE (DAPI) Project
  • 批准号:
    10697338
  • 项目类别:
  • 资助金额:
    $386.95万
  • 财政年份:
    2020
  • 负责人:
    Robert J Carroll
  • 依托单位:
Advancing Image Data Interoperability and Standards within an NIH Ecosystem (AIDISNE): A CHOP, FlyWheel, and Seven Bridges Integration Demonstration Project
  • 批准号:
    10690302
  • 项目类别:
  • 资助金额:
    $91.19万
  • 财政年份:
    2020
  • 负责人:
    Robert J Carroll
  • 依托单位:
Data Management and Portal for the INCLUDE (DAPI) Project
  • 批准号:
    10264912
  • 项目类别:
  • 资助金额:
    $386.95万
  • 财政年份:
    2020
  • 负责人:
    Robert J Carroll
  • 依托单位:
海外基金