Imaging Core

项目总结 癌症和代谢中心(CCM)的成像核心是技术服务和支持核心 针对CCM项目研究实验室和试点项目获得者。核心系列的综合服务 从简单显微镜的成像能力到复杂和先进的成像分析 成像方法。成像核心人员协助用户操作仪器和分析 成像数据。核心为该生物医学研究卓越中心的当前个人投资提供建议 (Cobre)应用程序使用成像核心进行特定研究。成像核心提供了 为Cobre Support第一阶段的项目提供巨大帮助，并将继续随时提供服务 所有Cobre实验室都可以方便地访问，以生成高质量的数据。朝向 提供高效和高质量的成像服务和建立强大的成像基础设施的目标 在CCM中，我们为核心添加了新功能和新成像系统。我们的具体目标是：1) 为Cobre调查人员提供针对项目的培训和咨询；2)制定和适应最新情况 ART成像技术，以加强早期和试点项目调查人员的研究；以及3) 开发和实施新方法，以增强CCM成像服务，并将此类服务提供给 Cobre和非Cobre用户。该核心将提供一个方便访问的设施，调查人员可以 使用各种成像系统评估他们的组织和/或细胞样本。贾建航博士， 成像核心主任，是一位高效的研究员，他成功地获得了大量 校外研究支持，包括NIGMS最大化调查人员研究奖(MIRA)(R35) 授予广泛依赖复杂成像能力的老牌调查人员奖。他曾经工作过 与所有毕业的科布雷PI密切合作，为他们成功获得 独立研究支持。贾博士指导了四个CCM研究项目的发展 第二阶段申请，他将继续为CCM调查人员提供关于使用 成像方式。

PROJECT SUMMARY The Imaging Core of the Center for Cancer and Metabolism (CCM) is the technical service and support core for CCM project research laboratories and pilot project recipients. The integrated services of the Core range from the imaging capabilities of simple microscopes to imaging analysis by sophisticated and advanced imaging methodologies. The Imaging Core personnel assist users to operate the instruments and analyze imaging data. The Core provides advice for the current PIs in this Center of Biomedical Research Excellence (COBRE) application to use the Imaging Core for their specific studies. The Imaging Core has provided tremendous help to the projects in Phase I of COBRE support and will continue to make its services readily available and easily accessible to all COBRE laboratories in order to generate high quality data. Toward the goals of providing efficient and high-quality imaging services and of establishing a robust imaging infrastructure within the CCM, we have added new features and new imaging systems to the Core. Our specific aims are: 1) to provide project-specific training and consultation for COBRE investigators; 2) to develop and adapt state-of- the art imaging techniques to enhance the research of early-stage and pilot project investigators; and 3) to develop and implement new methods, to enhance CCM imaging services and make such services available to COBRE and non-COBRE users. This Core will provide an easily accessible facility where investigators can evaluate their tissue and/or cellular samples using various types of imaging systems. Dr. Jianhang Jia, the Director of the Imaging Core, is a highly productive investigator who has successfully obtained substantial extramural research support including an NIGMS Maximizing Investigators' Research Award (MIRA) (R35) award for established investigators that relies extensively on sophisticated imaging capabilities. He has worked closely with all graduated COBRE PIs, making significant contributions to their successes in obtaining independent research support. Dr. Jia has guided the development of the four CCM research projects in this Phase II application, and he will continue to advise CCM investigators on the design of experiments that use imaging modalities.