Imaging Core

项目概要 癌症与代谢中心（CCM）的影像核心是技术服务和支持核心 适用于 CCM 项目研究实验室和试点项目接受者。核心系列的综合服务 从简单显微镜的成像功能到复杂和先进的成像分析 成像方法。 Imaging Core人员协助用户操作仪器并进行分析 成像数据。核心为生物医学卓越研究中心的现任 PI 提供建议 (COBRE) 应用程序使用成像核心进行特定研究。成像核心提供了 对COBRE支持的一期项目有巨大帮助，将继续做好服务 所有 COBRE 实验室均可轻松访问，以生成高质量数据。迈向 提供高效、高质量的影像服务和建立强大的影像基础设施的目标 在 CCM 中，我们向 Core 添加了新功能和新成像系统。我们的具体目标是：1） 为 COBRE 调查人员提供特定于项目的培训和咨询； 2）发展和适应现状 艺术成像技术，以加强早期和试点项目研究人员的研究； 3) 到 开发和实施新方法，以增强 CCM 成像服务并将此类服务提供给 COBRE 和非 COBRE 用户。该核心将提供一个易于访问的设施，调查人员可以 使用各种类型的成像系统评估他们的组织和/或细胞样本。贾建航博士 成像核心主任，是一位高产的研究人员，已成功获得大量 校外研究支持，包括 NIGMS 最大化研究者研究奖 (MIRA) (R35) 授予广泛依赖复杂成像能力的知名研究人员的奖项。他已经工作过 与所有毕业的 COBRE PI 密切合作，为他们成功获得 独立研究支持。贾博士指导了本年度四个CCM研究项目的开发 II 期应用，他将继续为 CCM 研究人员提供使用实验设计的建议 成像方式。

PROJECT SUMMARY The Imaging Core of the Center for Cancer and Metabolism (CCM) is the technical service and support core for CCM project research laboratories and pilot project recipients. The integrated services of the Core range from the imaging capabilities of simple microscopes to imaging analysis by sophisticated and advanced imaging methodologies. The Imaging Core personnel assist users to operate the instruments and analyze imaging data. The Core provides advice for the current PIs in this Center of Biomedical Research Excellence (COBRE) application to use the Imaging Core for their specific studies. The Imaging Core has provided tremendous help to the projects in Phase I of COBRE support and will continue to make its services readily available and easily accessible to all COBRE laboratories in order to generate high quality data. Toward the goals of providing efficient and high-quality imaging services and of establishing a robust imaging infrastructure within the CCM, we have added new features and new imaging systems to the Core. Our specific aims are: 1) to provide project-specific training and consultation for COBRE investigators; 2) to develop and adapt state-of- the art imaging techniques to enhance the research of early-stage and pilot project investigators; and 3) to develop and implement new methods, to enhance CCM imaging services and make such services available to COBRE and non-COBRE users. This Core will provide an easily accessible facility where investigators can evaluate their tissue and/or cellular samples using various types of imaging systems. Dr. Jianhang Jia, the Director of the Imaging Core, is a highly productive investigator who has successfully obtained substantial extramural research support including an NIGMS Maximizing Investigators' Research Award (MIRA) (R35) award for established investigators that relies extensively on sophisticated imaging capabilities. He has worked closely with all graduated COBRE PIs, making significant contributions to their successes in obtaining independent research support. Dr. Jia has guided the development of the four CCM research projects in this Phase II application, and he will continue to advise CCM investigators on the design of experiments that use imaging modalities.