Accelerating Excellence in Translational Science (AXIS)

加速转化科学的卓越发展 (AXIS)

• 批准号: 10283209
• 负责人: Jaydutt V. Vadgama
• 金额: $ 11.62万
• 依托单位: CHARLES R. DREW UNIVERSITY OF MED & SCI
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-28 至 2024-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10283209
• 关键词: AIDS/HIV problem; Affect; African American; Area; Behavioral; Bioinformatics; Cardiometabolic Disease; Cardiovascular Diseases; Center for Translational Science Activities; Chronic; Clinical; Clinical Research; Collaborations; Communicable Diseases; Communities; Community Services; County; Development; Diabetes Mellitus; Diagnosis; Discipline; Environmental Risk Factor; Epigenetic Process; Fostering; Goals; Health; Health Services; Hispanics; Hypertension; Incidence; Infrastructure; Institution; Intervention; Latino; Leadership; Location; Los Angeles; Malignant Neoplasms; Medical; Medicine; Mental Health; Mental Health Services; Mentors; Mission; Modeling; Molecular Genetics; Morbidity - disease rate; Obesity; Outcome; Pathway interactions; Research; Research Personnel; Research Training; Resources; Schools; Science; Services; Statistical Methods; Statistical Study; Strategic Planning; Technology; Tissues; Training and Education; Translating; Translational Research; Universities; Vision; biobank; cardiometabolism; care systems; clinical care; demographics; drug discovery; epidemiology study; experience; genomic data; health care availability; health disparity; minority health; mortality; next generation sequencing; precision medicine; programs; public health relevance; racial and ethnic; socioeconomics; success; treatment services

Abstract: Proposed Program Overview. The Charles R. Drew University of Medicine and Science proposes to continue the enhancement and success of the Accelerating Excellence in Translational Science (AXIS) Center. AXIS has shown to be the integrated hub for research conducted at CDU and continues to provide experienced leadership, and a myriad of clinical, translational, and community partnered activities. In the next five years, research will continue to grow and expand its enterprise alongside the Universities vision and mission to be a leader in eliminating health disparities by translating scientific discoveries into education, training, clinical care, treatment, and community service in three areas of focus which disproportionally affect Service Planning Area 6: Cancer, Cardiometabolic Disease (CMD), and HIV/AIDS. In addition, we look to build upon the application of Precision Medicine to understand and eliminate health disparities, while utilizing many of CDU’s outstanding resources in: Advanced Technologies such as Next Generation Sequencing for identifying Genomic Data; Drug Discovery; Integrated Clinical Tissues, Biorepository and Bio banking Facility; Clinical Studies/Trials Resources; Medical Bioinformatics; and Methods for Statistical and Epidemiological Studies. This approach will pave the pathway for CDU’s in becoming a competitive institution with sophisticated resources and services to better serve our communities. To accomplish this, we propose to continue with the three programmatic goals that align with the mission, vision, and strategic plan for the universities research enterprise: Goal 1: To enhance the infrastructure capacity in translational research using Precision Medicine model in the areas of Cancer, Cardiometabolic, and HIV/AIDS. Provide support for the emerging research pillars in Mental Health and Health Services Goal 2: To continue the integration of basic, clinical, behavioral and community-partnered research by fostering collaboration among disciplines, departments and schools at CDU, and sustainable collaboration with community leaders and investigators across other research institutions. Goal 3: To facilitate and elevate professional development and best practices in mentored clinical and translational research training on minority health and health disparities.

摘要：拟议计划概述。查尔斯·R·德鲁医学与科学大学提出 继续加强加速卓越转化科学 (AXIS) 并取得成功 中心。 AXIS 已被证明是基民盟研究的综合中心，并继续提供 经验丰富的领导力以及无数的临床、转化和社区合作活动。在接下来的 五年内，研究将与大学的愿景和使命一起不断发展和扩大其事业 通过将科学发现转化为教育、培训、临床，成为消除健康差距的领导者 护理、治疗和社区服务三个重点领域对服务规划的影响不成比例 领域 6：癌症、心脏代谢疾病 (CMD) 和艾滋病毒/艾滋病。此外，我们希望在此基础上 应用精准医学来了解和消除健康差异，同时利用基民盟的许多 优秀资源：先进技术，例如用于识别基因组的下一代测序 数据;药物发现；综合临床组织、生物样本库和生物银行设施；临床研究/试验 资源;医学生物信息学；统计和流行病学研究方法。这种方法将 为基民盟成为具有先进资源和服务的有竞争力的机构铺平道路 更好地服务我们的社区。为了实现这一目标，我们建议继续实现三个计划目标 与大学研究企业的使命、愿景和战略计划相一致： 目标 1：利用精准医学模式增强转化研究的基础设施能力 癌症、心脏代谢和艾滋病毒/艾滋病领域。为心理领域的新兴研究支柱提供支持 健康与保健服务 目标 2：通过促进基础、临床、行为和社区合作研究的持续整合 基民盟学科、院系和学校之间的合作，以及与社区的可持续合作 其他研究机构的领导者和研究人员。 目标 3：促进和提升指导性临床和治疗领域的专业发展和最佳实践 关于少数族裔健康和健康差异的转化研究培训。