Cancer Genomics Shared Resource

癌症基因组学共享资源摘要 癌症基因组学共享资源(CGSR)的使命是为共济会癌症中心(MCC)提供 研究人员能够广泛、深入和负担得起地获得最先进的基因组服务。除了……之外 CGSR的董事和工作人员保持着世界级的基因组仪器套件，帮助推动 通过咨询技术选择和工作流程，包括上游工作流程，为研究人员提供科学 准备和下游生物信息学和数据解释步骤。技术娴熟的员工可以执行所有 工作的技术部分或可以与调查员自己的实验室工作人员合作，提供 培训和获得他们本来无法使用的设备。CGSR检测的范围从 从传统的细胞遗传学到最新的单细胞和下一代测序技术。这些 使MCC研究人员能够解决与该病的病因、行为和治疗相关的关键问题 血液系统肿瘤和实体肿瘤。明尼苏达大学没有其他资源可以提供这些 为研究人员提供服务。 这一共享资源的结构和名称在上一个供资周期中发生了变化。具体地说， 细胞基因组学共享资源与明尼苏达大学基因组学中心的服务合并 (UMGC)成为CGSR。CGSR由Betsy Hirsch博士和Kenneth Beckman博士联合执导， 分别在细胞基因组学和分子基因组技术方面的专业知识将简化MCC的导航 成员通过在UMN提供的复杂的基因组分析谱。CGSR将确保 将注意力集中在MCC调查人员的具体科学需求上，同时受益于协同效应 这是由于与服务于整个大学社区的UMGC整合而产生的。在新的CGSR中， 将增加一名博士级别的全职相当于(FTE)研究科学家，专门致力于 为MCC成员定制工作，促进开发新的化验方法，生成试验数据，以及 癌症研究项目的进展。

Cancer Genomics Shared Resource Summary The mission of the Cancer Genomics Shared Resource (CGSR) is to provide Masonic Cancer Center (MCC) investigators with broad, deep, and affordable access to state-of-the-art genomic services. In addition to maintaining a world-class suite of genomic instrumentation, the Directors and staff of the CGSR help advance investigators' science through consultation about technology choices and workflows, including upstream preparative and downstream bioinformatics and data interpretation steps. The skilled staff can perform all of the technical components of the work or can collaborate with the investigator's own laboratory staff, providing training and access to equipment they would otherwise not be able to utilize. CGSR assays range from conventional cytogenetics to the most current single-cell and next-generation sequencing technologies. These enable MCC researchers to address critical questions relevant to the etiology, behavior, and treatment of hematologic and solid tumors. There is no other resource at the University of Minnesota that provides these services to researchers. The structure and name of this Shared Resource was changed during the last funding cycle. Specifically, the Cytogenomics Shared Resource merged with the services of the University of Minnesota Genomics Center (UMGC) to become the CGSR. The CGSR, co-directed by Drs. Betsy Hirsch and Kenneth Beckman, with expertise in cytogenomics and molecular genomic technologies, respectively, will simplify navigation by MCC members through the complex spectrum of genomic assays offered at the UMN. The CGSR will ensure focused attention on the specific scientific needs of MCC investigators while benefitting from the synergies resulting from integration with the UMGC which serves the entire University community. In the new CGSR, there will be an additional PhD-level full-time equivalent (FTE) Research Scientist devoted specifically to customized work for MCC members, facilitating the development of novel assays, generation of pilot data, and the advancement of cancer research projects.