Design and Analysis Core

设计与分析核心

• 批准号: 10338140
• 负责人: Richard N Jones
• 金额: $ 20.29万
• 依托单位: BUTLER HOSPITAL (PROVIDENCE, RI)
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-03-01 至 2024-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10338140
• 关键词: Address; Area; Behavioral; Center for Translational Science Activities; Centers of Research Excellence; Clinical; Clinical Research; Clinical Sciences; Collaborations; Communities; Complex; Computer software; Custom; Data; Data Analyses; Data Science; Data Security; Development; Educational workshop; Electrophysiology (science); Ensure; Environment; Experimental Designs; Faculty; Goals; High Performance Computing; Hospitals; Individual; Infrastructure; Investigation; Magnetic Resonance Imaging; Methodology; Methods; Mission; Neurosciences; Neurosciences Research; Procedures; Psychologist; Reproducibility; Research; Research Design; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Rhode Island; Series; Services; Speed; Statistical Models; System; Training; Training Activity; Translational Research; Translations; Validation; Work; clinical development; clinical outcome measures; community based research; complex data; computer science; computing resources; data management; design; epidemiology study; experience; experimental analysis; high dimensionality; imaging modality; interest; meetings; method development; neuroimaging; neuroregulation; programs; skills; sound; tool; training opportunity; translational neuroscience

Project Summary  The overall goals of the Design and Analysis Core (DAC) are to provide clinical translational neuroscience-­ relevant design and analytic resources to enhance and support COBRE Center for Neuromodulation (CCN)  projects, pilots and cores, and enhance the neuroscience research capacity at Butler Hospital specifically and  in Rhode Island, generally. The DAC will focus on providing support in three research contexts: planning,  support, and training. During planning stages, DAC will assist Project Leaders in crafting research design,  research infrastructure and resource planning, and development of data analysis plans. The goal is to generate  and support feasible designs that support and provide a mechanism to ensure and verify high quality data, and  reproducible data analysis and sound statistical inference. The DAC will provide and coordinate access to and  ensure responsible use of a computational support infrastructure at Butler Hospital that has been designed to  facilitate reproducible data analysis in the clinical neurosciences. The DAC supports its educational mission by  training PLs and their teams in application of computing tools and management of large and complex data. A  unique focus of the DAC is in the planning and design of studies that facilitate clinical translational  neuroscience research, meaning: we assist PLs in planning and analysis of complex and high dimensional  neuroscience data together with clinical (e.g., behavioral) data in order to speed translation of results and more  effectively communicate the clinical importance of the findings. Our long-­term goal is to grow into a resource  that serves the neuroscientists, psychologists and clinicians at Butler Hospital by providing a broad range of  statistical and high-­performance computing services. To support the CCN in achieving its mission, the DAC  has the following specific aims: Aim 1) Support CNN project leaders in the design and analysis;; Aim 2)  Enhance and refine existing computing infrastructure;; Aim 3) Enhance clinical neuroscience research in the  Rhode Island community.

项目总结