Enhancing Geroscience Scholarship and Faculty Development to Minimize Frailty and Maximize Healthspan
加强老年科学奖学金和教师发展,以最大限度地减少虚弱和最大限度地延长健康寿命
基本信息
- 批准号:10349503
- 负责人:
- 金额:$ 15.12万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-05-15 至 2023-01-31
- 项目状态:已结题
- 来源:
- 关键词:AdministratorAdultAffectAgeAgingArchitectureAwardBuffaloesCaringCessation of lifeClinical ResearchCollaborationsCommunitiesComplementContinuity of Patient CareDentistryDevelopmentDisadvantagedEducationEducational CurriculumEducational process of instructingElderlyEngineeringEnvironmentExtramural ActivitiesFosteringFoundationsGeriatricsGeroscienceGoalsGrantGrowthHealthHealthcare SystemsHomeHospitalizationImmigrantInfrastructureInterdisciplinary StudyInterventionInvestigationKnowledgeLawsLeadLeadershipMeasuresMedicineMentorsMentorshipNew YorkOlder PopulationOutcomePalliative MedicinePersonsPhysiologicalPopulation HeterogeneityPositioning AttributeQuality of lifeRecruitment ActivityRefugeesResearchResearch PersonnelResearch Project GrantsResearch SupportResearch TrainingResourcesRiskRisk FactorsRuralScholarshipScientistServicesStructureTeacher Professional DevelopmentTimeTrainingTranscendUnited StatesUniversitiesVisionWorkaging populationcareercareer developmentcomorbiditycurriculum developmentdisabilityeducation researchexperiencefall riskfallsfrailtyhealthspanimprovedinnovationmortalityolder patientpatient populationprogramsskillssocioeconomicsstemtraining opportunitytranslational scientist
项目摘要
Aging is the single most important risk factor for comorbidity and frailty. Frailty increases the risk of poor
outcomes that include falls, incident disability, hospitalization and mortality. Healthspan is the number of
years lived in a healthy, vital, and functionally capable state. Frailty and healthspan exist, then, in opposition
among the elderly and are at the core of optimal geriatric care. This NIA K07 Academic Leadership Career
Award will support Dr. Troen’s ongoing career development and help to protect his time and effort to build
the research support and mentorship infrastructure for the Center for Successful Aging (CSA), which focuses
on geroscience-related research and education at the University at Buffalo (UB). The goals of this proposal are
1) to advance innovative interdisciplinary and interprofessional collaborative research to detect, understand,
and minimize frailty and maximize healthspan in older adults and 2) to establish a robust mentorship,
educational, and research environment that fosters development of successful interdisciplinary geroscience
and geriatrics investigators. These goals will be accomplished through the candidate’s committed efforts and
leadership of the CSA, the breaking down of silos, and meaningful collaboration with the multitude of existing
resources for interdisciplinary research and interprofessional education and collaborative practice at UB.
Aging-related and geriatric research capacity will be enhanced through active recruitment of investigators,
partnerships with centers and departments across the entire university, a pilot grant program, and an annual
research retreat. This will enhance interdisciplinary research, establish an optimal environment for
mentorship, and support development and competing for extramural grants. Faculty development and
mentorship will be supported through mentorship committees, a new geroscience curriculum, regular
seminars, and an emphasis on interdisciplinary research and training opportunities. The candidate has the
necessary scientific expertise, leadership skills, clinical and research training, and mentoring and teaching
experience to lead the CSA, implement a program of curriculum development, and accomplish the stated aims
of this proposal. He will build on existing infrastructure at UB to develop and train a diverse pool of highly-
trained scientists who will conduct important research to Minimize Frailty and Maximize Healthspan. This
application holds great promise in developing an interdisciplinary research and mentoring program that
transcends traditional boundaries and that will enhance knowledge and ultimately improve the care of the
aging population.
衰老是合并症和虚弱的最重要的风险因素。脆弱增加了穷人的风险
结局包括福尔斯、意外残疾、住院和死亡。Healthspan是指
年生活在一个健康的,充满活力的,和功能能力的状态。那么,虚弱和健康是对立的
在老年人中,这是最佳老年护理的核心。此NIA K 07学术领导生涯
该奖项将支持Troen博士正在进行的职业发展,并有助于保护他的时间和精力,
成功老龄化中心(CSA)的研究支持和指导基础设施,重点是
在布法罗大学(UB)进行老年科学相关的研究和教育。本提案的目标是
1)推进创新的跨学科和跨专业的合作研究,以检测,了解,
最大限度地减少老年人的脆弱性,最大限度地延长老年人的健康寿命; 2)建立一个强大的导师制度,
教育和研究环境,促进成功的跨学科老年科学的发展
和老年医学调查员这些目标将通过候选人的努力实现,
CSA的领导,打破孤岛,以及与众多现有的
在UB跨学科研究和跨专业教育和合作实践的资源。
将通过积极征聘调查人员,加强与老龄化有关的研究能力和老年医学研究能力,
与整个大学的中心和部门合作,试点赠款计划,以及年度
研究静修这将加强跨学科研究,建立一个最佳环境,
指导,并支持发展和竞争校外赠款。教师发展和
将通过指导委员会、新的老年科学课程、定期
研讨会,并强调跨学科的研究和培训机会。候选人有
必要的科学专业知识、领导技能、临床和研究培训以及指导和教学
领导CSA的经验,实施课程开发计划,并实现既定目标
这一提议。他将在UB现有基础设施的基础上,开发和培训一个多样化的高度-
训练有素的科学家将进行重要的研究,以最大限度地减少虚弱和最大限度地延长健康寿命。这
应用程序在开发跨学科研究和指导计划方面具有很大的希望,
超越了传统的界限,这将提高知识,并最终改善护理的
人口老龄化
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Bruce R. Troen其他文献
Effects of a 6-Week Treadmill Training With and Without Virtual Reality on Frailty in People With Multiple Sclerosis
为期6周有虚拟现实和无虚拟现实的跑步机训练对多发性硬化症患者虚弱状况的影响
- DOI:
10.1016/j.apmr.2024.09.010 - 发表时间:
2025-02-01 - 期刊:
- 影响因子:3.700
- 作者:
Tobia Zanotto;Irina Galperin;Danya Pradeep Kumar;Anat Mirelman;Shahar Yehezkyahu;Keren Regev;Arnon Karni;Tanja Schmitz-Hübsch;Friedemann Paul;Sharon G. Lynch;Abiodun E. Akinwuntan;Jianghua He;Bruce R. Troen;Hannes Devos;Jeffrey M. Hausdorff;Jacob J. Sosnoff - 通讯作者:
Jacob J. Sosnoff
Comparative Responsiveness of HL-60, HL-60R, and HL-60R<sup>+</sup> (LRARSN) Cells to Retinoic Acid, Calcitriol, 9 <em>cis</em>-Retinoic Acid, and Sodium Butyrate
- DOI:
10.1182/blood.v86.7.2475.2475 - 发表时间:
1995-10-01 - 期刊:
- 影响因子:
- 作者:
Kevin B. Atkins;Bruce R. Troen - 通讯作者:
Bruce R. Troen
Cloning and expression of the gene for the major excreted protein of transformed mouse fibroblasts. A secreted lysosomal protease regulated by transformation.
转化小鼠成纤维细胞主要分泌蛋白基因的克隆和表达。
- DOI:
10.1016/s0021-9258(19)57386-0 - 发表时间:
1988 - 期刊:
- 影响因子:0
- 作者:
Bruce R. Troen;D. Ascherman;Daphne Atlas;Michael M. Gottesman - 通讯作者:
Michael M. Gottesman
Resveratrol: Effects on Lipids and Cardiovascular Risk
白藜芦醇:对血脂和心血管风险的影响
- DOI:
10.1007/s12170-012-0289-2 - 发表时间:
2013 - 期刊:
- 影响因子:1.9
- 作者:
E. Cherniack;E. Cherniack;Bruce R. Troen;Bruce R. Troen - 通讯作者:
Bruce R. Troen
Bruce R. Troen的其他文献
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{{ truncateString('Bruce R. Troen', 18)}}的其他基金
Promoting cognitive resilience and reducing frailty in older Veterans with bright light therapy
通过强光疗法提高老年退伍军人的认知能力并减少虚弱
- 批准号:
10590503 - 财政年份:2023
- 资助金额:
$ 15.12万 - 项目类别:
High Intensity Interval Training (HIIT) to Reduce Frailty and Enhance Resilience in Older Veterans
高强度间歇训练(HIIT)可减少老年退伍军人的虚弱并增强其恢复能力
- 批准号:
10539160 - 财政年份:2023
- 资助金额:
$ 15.12万 - 项目类别:
The impacts of vitamin D status and HIIT on physical performance and frailty during aging
维生素 D 状态和 HIIT 对衰老过程中身体机能和虚弱的影响
- 批准号:
10229660 - 财政年份:2020
- 资助金额:
$ 15.12万 - 项目类别:
ShEEP Request for Intracellular and Extracellular Protein Signaling Station (IEPSS)
ShEEP 请求细胞内和细胞外蛋白质信号转导站 (IEPSS)
- 批准号:
10178936 - 财政年份:2020
- 资助金额:
$ 15.12万 - 项目类别:
Enhancing Geroscience Scholarship and Faculty Development to Minimize Frailty and Maximize Healthspan
加强老年科学奖学金和教师发展,以最大限度地减少虚弱和最大限度地延长健康寿命
- 批准号:
9927970 - 财政年份:2019
- 资助金额:
$ 15.12万 - 项目类别:
High intensity interval training and nicotinamide riboside treatment to enhance functional capacity and reduce frailty during aging
高强度间歇训练和烟酰胺核苷治疗可增强功能能力并减少衰老过程中的虚弱
- 批准号:
10663245 - 财政年份:2019
- 资助金额:
$ 15.12万 - 项目类别:
Enhancing Geroscience Scholarship and Faculty Development to Minimize Frailty and Maximize Healthspan
加强老年科学奖学金和教师发展,以最大限度地减少虚弱和最大限度地延长健康寿命
- 批准号:
10581712 - 财政年份:2019
- 资助金额:
$ 15.12万 - 项目类别:
High intensity interval training and nicotinamide riboside treatment to enhance functional capacity and reduce frailty during aging
高强度间歇训练和烟酰胺核苷治疗可增强功能能力并减少衰老过程中的虚弱
- 批准号:
10266089 - 财政年份:2019
- 资助金额:
$ 15.12万 - 项目类别:
High intensity interval training and nicotinamide riboside treatment to enhance functional capacity and reduce frailty during aging
高强度间歇训练和烟酰胺核苷治疗可增强功能能力并减少衰老过程中的虚弱
- 批准号:
10477288 - 财政年份:2019
- 资助金额:
$ 15.12万 - 项目类别:
High intensity interval training and nicotinamide riboside treatment to enhance functional capacity and reduce frailty during aging
高强度间歇训练和烟酰胺核苷治疗可增强功能能力并减少衰老过程中的虚弱
- 批准号:
9974279 - 财政年份:2019
- 资助金额:
$ 15.12万 - 项目类别:
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