Enhancing Geroscience Scholarship and Faculty Development to Minimize Frailty and Maximize Healthspan
Enhancing Geroscience Scholarship and Faculty Development to Minimize Frailty and Maximize Healthspan
批准号:
10581712
负责人:
Bruce R. Troen
金额:
$14.94万
依托单位国家:
美国
项目类别:
财政年份:
2019
资助国家:
美国
项目状态:
未结题
起止时间:
2019-05-15 至 2025-01-31
关键词:
AdministratorAdultAffectAgeAgingArchitectureAwardCaringCessation of lifeCollaborationsComplementContinuity of Patient CareDentistryDevelopmentEducationEducational CurriculumEducational process of instructingElderlyEngineeringEnvironmentExtramural ActivitiesFosteringFoundationsGeriatricsGeroscienceGoalsGrantGrowthHealthHealthcare SystemsHomeHospitalizationImmigrantInfrastructureInstitutionInterdisciplinary StudyInterventionInvestigationInvestmentsKnowledgeLawsLeadLeadershipMeasuresMedicineMentorsMentorshipNew YorkOlder PopulationOutcomePalliative MedicinePersonsPhysiologicalPopulation HeterogeneityPositioning AttributeQuality of lifeRecruitment ActivityRefugeesResearchResearch PersonnelResearch Project GrantsResearch SupportResearch TrainingResourcesRiskRisk FactorsRuralScholarshipScientistServicesStructureTeacher Professional DevelopmentTimeTrainingTranscendUnited StatesUniversitiesVisionWorkaging populationcareercareer developmentclinical trainingcomorbiditycurriculum developmentdisabilityexperiencefall riskfallsfrailtyhealthspanimprovedinnovationmortalityneighborhood disadvantageolder patientpatient populationprogramsskills trainingsocioeconomicsstemtraining opportunitytranslational scientist
中文摘要
衰老是合并症和虚弱的最重要的风险因素。脆弱增加了穷人的风险
结局包括福尔斯、意外残疾、住院和死亡。Healthspan是指
年生活在一个健康的,充满活力的,和功能能力的状态。那么,虚弱和健康是对立的
在老年人中,这是最佳老年护理的核心。此NIA K 07学术领导生涯
该奖项将支持Troen博士正在进行的职业发展,并有助于保护他的时间和精力,
成功老龄化中心(CSA)的研究支持和指导基础设施,重点是
在布法罗大学(UB)进行老年科学相关的研究和教育。本提案的目标是
1)推进创新的跨学科和跨专业的合作研究,以检测,了解,
最大限度地减少老年人的脆弱性,最大限度地延长老年人的健康寿命; 2)建立一个强大的导师制度,
教育和研究环境,促进成功的跨学科老年科学的发展
和老年医学调查员这些目标将通过候选人的努力实现,
CSA的领导,打破孤岛,以及与众多现有的
在UB跨学科研究和跨专业教育和合作实践的资源。
将通过积极征聘调查人员,加强与老龄化有关的研究能力和老年医学研究能力,
与整个大学的中心和部门合作,试点赠款计划,以及年度
研究静修这将加强跨学科研究,建立一个最佳环境,
指导,并支持发展和竞争校外赠款。教师发展和
将通过指导委员会、新的老年科学课程、定期
研讨会,并强调跨学科的研究和培训机会。候选人有
必要的科学专业知识、领导技能、临床和研究培训以及指导和教学
领导CSA的经验,实施课程开发计划,并实现既定目标
这一提议。他将在UB现有基础设施的基础上,开发和培训一个多样化的高度-
训练有素的科学家将进行重要的研究,以最大限度地减少虚弱和最大限度地延长健康寿命。这
应用程序在开发跨学科研究和指导计划方面具有很大的希望,
超越了传统的界限,这将提高知识,并最终改善护理的
人口老龄化
英文摘要
Aging is the single most important risk factor for comorbidity and frailty. Frailty increases the risk of poor
outcomes that include falls, incident disability, hospitalization and mortality. Healthspan is the number of
years lived in a healthy, vital, and functionally capable state. Frailty and healthspan exist, then, in opposition
among the elderly and are at the core of optimal geriatric care. This NIA K07 Academic Leadership Career
Award will support Dr. Troen’s ongoing career development and help to protect his time and effort to build
the research support and mentorship infrastructure for the Center for Successful Aging (CSA), which focuses
on geroscience-related research and education at the University at Buffalo (UB). The goals of this proposal are
1) to advance innovative interdisciplinary and interprofessional collaborative research to detect, understand,
and minimize frailty and maximize healthspan in older adults and 2) to establish a robust mentorship,
educational, and research environment that fosters development of successful interdisciplinary geroscience
and geriatrics investigators. These goals will be accomplished through the candidate’s committed efforts and
leadership of the CSA, the breaking down of silos, and meaningful collaboration with the multitude of existing
resources for interdisciplinary research and interprofessional education and collaborative practice at UB.
Aging-related and geriatric research capacity will be enhanced through active recruitment of investigators,
partnerships with centers and departments across the entire university, a pilot grant program, and an annual
research retreat. This will enhance interdisciplinary research, establish an optimal environment for
mentorship, and support development and competing for extramural grants. Faculty development and
mentorship will be supported through mentorship committees, a new geroscience curriculum, regular
seminars, and an emphasis on interdisciplinary research and training opportunities. The candidate has the
necessary scientific expertise, leadership skills, clinical and research training, and mentoring and teaching
experience to lead the CSA, implement a program of curriculum development, and accomplish the stated aims
of this proposal. He will build on existing infrastructure at UB to develop and train a diverse pool of highly-
trained scientists who will conduct important research to Minimize Frailty and Maximize Healthspan. This
application holds great promise in developing an interdisciplinary research and mentoring program that
transcends traditional boundaries and that will enhance knowledge and ultimately improve the care of the
aging population.
期刊论文(11)
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DOI:
10.1016/j.imbio.2020.152003
发表时间:
2020-09
期刊:
IMMUNOBIOLOGY
影响因子:
2.8
作者:
[Seldeen, Kenneth L., Thiyagarajan, Ramkumar, Redae, Yonas, Jacob, Alexander, Troen, Bruce R., Quigg, Richard J., Alexander, Jessy J.]
通讯作者:
Alexander, Jessy J.
DOI:
10.20900/agmr20210007
发表时间:
2021-02
期刊:
Advances in geriatric medicine and research
影响因子:
--
作者:
[K. Seldeen;B. Troen]
通讯作者:
K. Seldeen;B. Troen
Falls: To D or Not to D-That Is Not the (Only) Question!
跌倒:去 D 还是不去 D——这不是(唯一的)问题!
DOI:
10.7326/m20-7609
发表时间:
2021
期刊:
Annals of internal medicine
影响因子:
39.2
作者:
[Troen,BruceR]
通讯作者:
Troen,BruceR
DOI:
10.1126/sciadv.abe5671
发表时间:
2021-09-03
期刊:
Science advances
影响因子:
13.6
作者:
[Shahini A, Rajabian N, Choudhury D, Shahini S, Vydiam K, Nguyen T, Kulczyk J, Santarelli T, Ikhapoh I, Zhang Y, Wang J, Liu S, Stablewski A, Thiyagarajan R, Seldeen K, Troen BR, Peirick J, Lei P, Andreadis ST]
通讯作者:
Andreadis ST
DOI:
10.1016/j.nut.2021.111189
发表时间:
2021-07
期刊:
Nutrition (Burbank, Los Angeles County, Calif.)
影响因子:
--
作者:
[Seldeen KL, Shahini A, Thiyagarajan R, Redae Y, Leiker M, Rajabian N, Dynka A, Andreadis ST, Troen BR]
通讯作者:
Troen BR
共 6 条
Promoting cognitive resilience and reducing frailty in older Veterans with bright light therapy
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批准号:10590503
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2023
-
负责人:Bruce R. Troen
-
依托单位:
High Intensity Interval Training (HIIT) to Reduce Frailty and Enhance Resilience in Older Veterans
-
批准号:10539160
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2023
-
负责人:Bruce R. Troen
-
依托单位:
The impacts of vitamin D status and HIIT on physical performance and frailty during aging
-
批准号:10229660
-
项目类别:
-
资助金额:$75.97万
-
财政年份:2020
-
负责人:Bruce R. Troen
-
依托单位:
ShEEP Request for Intracellular and Extracellular Protein Signaling Station (IEPSS)
-
批准号:10178936
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2020
-
负责人:Bruce R. Troen
-
依托单位:
Enhancing Geroscience Scholarship and Faculty Development to Minimize Frailty and Maximize Healthspan
-
批准号:10349503
-
项目类别:
-
资助金额:$15.12万
-
财政年份:2019
-
负责人:Bruce R. Troen
-
依托单位:
Enhancing Geroscience Scholarship and Faculty Development to Minimize Frailty and Maximize Healthspan
-
批准号:9927970
-
项目类别:
-
资助金额:$15.76万
-
财政年份:2019
-
负责人:Bruce R. Troen
-
依托单位:
High intensity interval training and nicotinamide riboside treatment to enhance functional capacity and reduce frailty during aging
-
批准号:10663245
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2019
-
负责人:Bruce R. Troen
-
依托单位:
High intensity interval training and nicotinamide riboside treatment to enhance functional capacity and reduce frailty during aging
-
批准号:10266089
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2019
-
负责人:Bruce R. Troen
-
依托单位:
High intensity interval training and nicotinamide riboside treatment to enhance functional capacity and reduce frailty during aging
-
批准号:9974279
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2019
-
负责人:Bruce R. Troen
-
依托单位:
ShEEP Request for Keyence BZ-X800E All-in-One Fluorescence Microscope
-
批准号:9907801
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2019
-
负责人:Bruce R. Troen
-
依托单位:
High intensity interval training and nicotinamide riboside treatment to enhance functional capacity and reduce frailty during aging
-
批准号:10477288
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2019
-
负责人:Bruce R. Troen
-
依托单位:
Enhancing functional capacity in older adults with short session high intensity interval training
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批准号:10174857
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2018
-
负责人:Bruce R. Troen
-
依托单位:
Enhancing functional capacity in older adults with short session high intensity interval training
-
批准号:10540222
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2018
-
负责人:Bruce R. Troen
-
依托单位:
Physical performance in an animal model of vitamin D insufficiency
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批准号:9001836
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2013
-
负责人:Bruce R. Troen
-
依托单位:
Differential Impact of Resveratrol and Resveratrol Mimetics Upon Aging Bone
-
批准号:8244933
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2011
-
负责人:Bruce R. Troen
-
依托单位:
Differential Impact of Resveratrol and Resveratrol Mimetics Upon Aging Bone
-
批准号:8142638
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2011
-
负责人:Bruce R. Troen
-
依托单位:
Differential Impact of Resveratrol and Resveratrol Mimetics Upon Aging Bone
-
批准号:8696776
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2011
-
负责人:Bruce R. Troen
-
依托单位:
Differential Impact of Resveratrol and Resveratrol Mimetics Upon Aging Bone
-
批准号:8397565
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2011
-
负责人:Bruce R. Troen
-
依托单位:
CATHEPSIN EXPRESSION IN OSTEOCLASTS DURING AGING
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批准号:6130339
-
项目类别:
-
资助金额:$7.85万
-
财政年份:1998
-
负责人:Bruce R. Troen
-
依托单位:
REGULATION OF CATHEPSIN L GENE EXPRESSION
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批准号:6244633
-
项目类别:
-
资助金额:$2.22万
-
财政年份:1997
-
负责人:Bruce R. Troen
-
依托单位:
海外基金