Post-Surgical Predictors of Depression and Weight Regain after Bariatric Surgery

减肥手术后抑郁症和体重恢复的术后预测因素

• 批准号: 10000130
• 负责人: SCOTT G ENGEL
• 金额: $ 67.34万
• 依托单位: SANFORD RESEARCH NORTH
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-15 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10000130
• 关键词: Affect; Behavior; Behavioral; Body Weight decreased; Clinical; Data; Development; Disinhibition; Eating; Ecological momentary assessment; Environment; Impulsivity; Lead; Measures; Mediating; Mental Depression; Modeling; Morbid Obesity; Operative Surgical Procedures; Outcome; Participant; Patient Self-Report; Patients; Play; Process; Prospective Studies; Recurrence; Risk; Stress; Techniques; Testing; Time; Weight; adult obesity; bariatric surgery; design; experience; improved; longitudinal design; loss of control over eating; negative affect; obesity treatment; outcome prediction; predictive modeling; prevent; prospective; psychologic

Abstract: Recent studies have clearly indicated that a significant proportion of bariatric surgery patients experience substantial weight regain and struggle with depression following their surgery. Understanding the mechanisms that contribute to these negative clinical outcomes is of considerable scientific and clinical importance. In the present study, we propose a model of predictors that we believe result in weight regain and depression. We will test the idea that in the moment, stress and negative affect predict loss of control eating, and that over time, loss of control eating predicts weight regain and depression in these patients. We will also investigate the influence of disinhibition on these relationships. Furthermore, we will use contemporary ecological momentary assessment and ambulatory assessment techniques to measure these variables and study their relationship to weight regain and depression in a prospective, longitudinal design. Finally, we will longitudinally examine weight regain and depression following bariatric surgery to clarify the temporal relationship between these variables.

摘要： 最近的研究清楚地表明，减肥手术患者的经验， 手术后体重大幅反弹，并与抑郁症作斗争。了解机制 导致这些负面临床结果的因素具有相当大的科学和临床重要性。在 目前的研究，我们提出了一个模型的预测因素，我们认为，在体重反弹和抑郁症的结果。我们 我将测试一下这个想法，在那一刻，压力和负面影响预示着饮食失控， 随着时间的推移，饮食失控预示着这些患者的体重反弹和抑郁。我们亦会研究 去抑制对这些关系的影响。此外，我们将利用当代生态 瞬时评估和动态评估技术来测量这些变量，并研究其 在一项前瞻性纵向设计中，最后，我们将纵向 检查减肥手术后体重恢复和抑郁症，以澄清 这些变量。