Context, Subjective and Cognitive Experiences with Patterns of Tobacco and Cannabis Co-Use in Young Adults

年轻人烟草和大麻共同使用模式的背景、主观和认知体验

• 批准号: 10378068
• 负责人: Robin J. Mermelstein
• 金额: $ 69.73万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10378068
• 关键词: Address; Affective; Alcohol consumption; Behavior; Behavioral; Cannabis; Characteristics; Cognition; Cognitive; Consumption; Data; Data Collection; Dependence; Devices; Ecological momentary assessment; Electronic Nicotine Delivery Systems; Enrollment; Failure; Future; Gender; Goals; Health; Hour; Illinois; Individual; Individual Differences; Intervention; Knowledge; Legal; Location; Methodology; Methods; Moods; Neurocognitive; Nicotine; Outcome; Participant; Pattern; Performance; Persons; Policies; Prevention; Probability; Problem behavior; Public Health; Reaction; Reporting; Research; Risk Factors; Sampling; Short-Term Memory; Smoking; Social Environment; Surveys; Time; Tobacco; Tobacco use; Vaporizer; Work; aged; base; behavioral outcome; electronic liquid; experience; inclusion criteria; marijuana use; negative mood; non-cigarette tobacco product; positive mood; psychosocial; response; social; substance use; tobacco products; tobacco user; vaping; vapor; young adult

Co-use of tobacco and cannabis has been increasing, especially among young adults in the US, with more than 20% of young adults aged 18-24 reporting use of both substances in the past month. There is growing evidence that co-use of these substances increases the health consequences and problematic psychosocial outcomes of either alone, and that use of one product increases the probability of use and failure to stop the other. Co-use is a broad term and may encompass using both substances within a given time frame (e.g., past month), within a given episode (concurrent use), in sequence (chasing), or mixed together in the same delivery device (co- administration). Until recently, co-use was also generally limited to combustible methods, either smoking each product separately or combining them (e.g., in blunts or spliffs). With the increase in electronic nicotine delivery systems (ENDS) as well as the increase in states legalizing recreational cannabis, there are new options for co- use, and ENDS devices that vape e-liquids containing nicotine are becoming more popular methods to consume cannabis. Although research on co-use is growing, there have been numerous methodological limitations of prior work, including a lack of detailed data about differences in specific patterns of co-use and modes of delivery, especially given the rising popularity of alternative tobacco products, as well as a reliance on survey data. Less is known about the factors that may contribute to the different patterns of co-use in young adults, that may maintain co-use, and that may be associated with different outcomes. The overall goal of this study is to examine the situational, momentary factors associated with the different patterns of tobacco and cannabis co-use, how they may vary by delivery mode, and how they are associated with changes in behavioral outcomes (e.g., dependence, changes in rates of use, problem behaviors). This project will use ecological momentary assessment (EMA) to gather in-depth, real-time naturalistic reports of 425 young adult (aged 18-25) tobacco and cannabis co-users’ daily experiences and product use behaviors. Across two waves of EMA, we will capture episodes in which young adults use each product alone as well as when they use them concurrently (during the same episode), either in a common delivery device (e.g., blunt or vaporizer) or in succession. We will examine how the proximal context in which the combination of product use occurs and the individual's subjective, affective, and neurocognitive reactions to those use experiences vary by delivery mode (combustible or vaporized) and individual characteristics, and how these factors influence future tobacco and cannabis use patterns. Knowledge gained will provide needed evidence about the behavioral and neurocognitive consequences of co-use use that will help better inform prevention, intervention, and policy approaches to reducing harms of both products. This project is also timely in that its data collection occurs in a state (Illinois) that will have just legalized recreational cannabis use (effective January, 2020).

烟草和大麻的共同使用一直在增加，特别是在美国的年轻人中，超过 20% 的 18-24 岁年轻人报告在过去一个月使用过这两种物质。越来越多的证据 共同使用这些物质会增加健康后果和有问题的心理社会后果 单独使用一种产品会增加使用另一种产品且无法阻止另一种产品的可能性。共同使用是 一个广泛的术语，可能涵盖在给定时间范围内（例如，上个月）、在一定时间内使用这两种物质 给定的情节（同时使用），按顺序（追逐），或在同一传输设备中混合在一起（共同使用） 行政）。直到最近，共同使用还通常仅限于可燃方法，要么各自吸烟 单独或组合产品（例如，钝器或接头）。随着电子尼古丁输送量的增加 系统（ENDS）以及娱乐性大麻合法化州的增加，有新的选择 使用和使用含有尼古丁的电子烟液的 ENDS 设备正在成为更流行的消费方式 大麻。尽管对共同使用的研究不断增长，但仍存在许多方法学上的局限性 先前的工作，包括缺乏有关特定共同使用模式和交付方式差异的详细数据， 特别是考虑到替代烟草产品日益流行以及对调查数据的依赖。较少的 了解可能导致年轻人不同共同使用模式的因素，这些因素可能 保持共同使用，这可能会带来不同的结果。本研究的总体目标是检验 与烟草和大麻共同使用的不同模式相关的情境性、瞬时因素，如何 它们可能因交付模式以及它们与行为结果变化的关系而异（例如， 依赖性、使用率的变化、问题行为）。本项目将采用生态瞬时 评估 (EMA)，收集 425 名年轻人（18-25 岁）烟草和烟草制品的深入、实时、自然的报告 大麻共同使用者的日常经历和产品使用行为。在两波 EMA 中，我们将捕获 年轻人单独使用每种产品以及同时使用这些产品的情况（在 相同的情节），无论是在共同的输送设备（例如钝器或汽化器）中还是连续输送。我们将检查 产品使用发生的最接近环境与个人的主观、情感、 对这些使用体验的神经认知反应因交付模式（可燃或汽化）而异 个人特征，以及这些因素如何影响未来的烟草和大麻使用模式。知识 获得的结果将提供有关共同使用的行为和神经认知后果的必要证据 将有助于更好地为预防、干预和政策方法提供信息，以减少这两种产品的危害。这 该项目也是及时的，因为它的数据收集发生在刚刚将娱乐合法化的州（伊利诺伊州） 大麻的使用（2020 年 1 月生效）。