Context, Subjective and Cognitive Experiences with Patterns of Tobacco and Cannabis Co-Use in Young Adults

年轻人烟草和大麻共同使用模式的背景、主观和认知体验

• 批准号: 10378068
• 负责人: Robin J. Mermelstein
• 金额: $ 69.73万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10378068
• 关键词: Address; Affective; Alcohol consumption; Behavior; Behavioral; Cannabis; Characteristics; Cognition; Cognitive; Consumption; Data; Data Collection; Dependence; Devices; Ecological momentary assessment; Electronic Nicotine Delivery Systems; Enrollment; Failure; Future; Gender; Goals; Health; Hour; Illinois; Individual; Individual Differences; Intervention; Knowledge; Legal; Location; Methodology; Methods; Moods; Neurocognitive; Nicotine; Outcome; Participant; Pattern; Performance; Persons; Policies; Prevention; Probability; Problem behavior; Public Health; Reaction; Reporting; Research; Risk Factors; Sampling; Short-Term Memory; Smoking; Social Environment; Surveys; Time; Tobacco; Tobacco use; Vaporizer; Work; aged; base; behavioral outcome; electronic liquid; experience; inclusion criteria; marijuana use; negative mood; non-cigarette tobacco product; positive mood; psychosocial; response; social; substance use; tobacco products; tobacco user; vaping; vapor; young adult

Co-use of tobacco and cannabis has been increasing, especially among young adults in the US, with more than 20% of young adults aged 18-24 reporting use of both substances in the past month. There is growing evidence that co-use of these substances increases the health consequences and problematic psychosocial outcomes of either alone, and that use of one product increases the probability of use and failure to stop the other. Co-use is a broad term and may encompass using both substances within a given time frame (e.g., past month), within a given episode (concurrent use), in sequence (chasing), or mixed together in the same delivery device (co- administration). Until recently, co-use was also generally limited to combustible methods, either smoking each product separately or combining them (e.g., in blunts or spliffs). With the increase in electronic nicotine delivery systems (ENDS) as well as the increase in states legalizing recreational cannabis, there are new options for co- use, and ENDS devices that vape e-liquids containing nicotine are becoming more popular methods to consume cannabis. Although research on co-use is growing, there have been numerous methodological limitations of prior work, including a lack of detailed data about differences in specific patterns of co-use and modes of delivery, especially given the rising popularity of alternative tobacco products, as well as a reliance on survey data. Less is known about the factors that may contribute to the different patterns of co-use in young adults, that may maintain co-use, and that may be associated with different outcomes. The overall goal of this study is to examine the situational, momentary factors associated with the different patterns of tobacco and cannabis co-use, how they may vary by delivery mode, and how they are associated with changes in behavioral outcomes (e.g., dependence, changes in rates of use, problem behaviors). This project will use ecological momentary assessment (EMA) to gather in-depth, real-time naturalistic reports of 425 young adult (aged 18-25) tobacco and cannabis co-users’ daily experiences and product use behaviors. Across two waves of EMA, we will capture episodes in which young adults use each product alone as well as when they use them concurrently (during the same episode), either in a common delivery device (e.g., blunt or vaporizer) or in succession. We will examine how the proximal context in which the combination of product use occurs and the individual's subjective, affective, and neurocognitive reactions to those use experiences vary by delivery mode (combustible or vaporized) and individual characteristics, and how these factors influence future tobacco and cannabis use patterns. Knowledge gained will provide needed evidence about the behavioral and neurocognitive consequences of co-use use that will help better inform prevention, intervention, and policy approaches to reducing harms of both products. This project is also timely in that its data collection occurs in a state (Illinois) that will have just legalized recreational cannabis use (effective January, 2020).

烟草和大麻的共同使用一直在增加，尤其是在美国的年轻人中，超过 在过去一个月中，有20％的年轻人在18-24岁的年轻人报告两种物质。越来越多的证据 这些物质的共同使用会增加健康后果和问题的心理社会心理结局 要么单独使用，而且一种产品的使用会增加使用的可能性和无法阻止另一个产品的可能性。共用是 广义术语，可以在给定时间范围内使用这两种物质（例如，过去一个月）， 给定发作（同时使用），序列（追逐）或在同一输送设备中混合在一起（共同 行政）。直到最近，共同利用通常还限于混合方法，要么吸烟 分别产品或组合它们（例如，钝或泡沫）。随着电子尼古丁传递的增加 系统（结束）以及使娱乐性大麻合法化的州的增加，有新的选择 使用，并结束vape E-liquids含有尼古丁的设备正在成为越来越流行的方法 尽管关于共用的研究正在增长，但有许多方法论上的局限性 先前的工作，包括缺乏有关共同使用特定模式和交付方式差异的详细数据， 特别是考虑到替代烟草产品的普及以及调查数据的缓解。较少的 已经知道可能导致年轻人共同使用模式的因素，这可能 保持共同使用，这可能与不同的结果有关。这项研究的总体目标是检查 与烟草和大麻的不同模式相关的情境，瞬时因素，如何使用 它们可能因交付模式而有所不同，以及它们与行为结果的变化如何相关（例如， 依赖性，使用率的变化，问题行为）。该项目将使用生态瞬间 评估（EMA）收集425名年轻人（18-25岁）烟草和 大麻联合使用者的日常体验和产品使用行为。在两波EMA浪潮中，我们将捕获 年轻人单独使用每种产品以及同时使用它们的情节（在 同一情节），无论是在常见的输送设备（例如钝器还是蒸发器）中，还是连续的。我们将检查 产品使用结合的近端环境以及个人的主观，情感， 对使用经验的神经认知反应因传递模式（可燃或蒸发）而异 个人特征，以及这些因素如何影响未来的烟草和大麻使用模式。知识 获得的将提供有关共同使用的行为和神经认知后果所需的证据 将有助于更好地告知预防，干预和政策方法，以减少两种产品的危害。这 项目也及时，其数据收集发生在伊利诺伊州（伊利诺伊州）的状态，这将使娱乐活动合法化 使用大麻（自2020年1月生效）。