Center for Coordination of Analysis, Science, Enhancement, and Logistics (CASEL) in Tobacco Regulatory Science

烟草监管科学分析、科学、增强和物流协调中心 (CASEL)

• 批准号: 10662756
• 负责人: Robin J. Mermelstein
• 金额: $ 370.15万
• 依托单位: WESTAT, INC.
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-30 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10662756
• 关键词: Acceleration; Achievement; Address; Adoption; Agreement; Award; Behavior; Centers for Disease Control and Prevention (U.S.); Collaborations; Communities; Complement; Consensus; Data; Decision Making; Development; Directories; Discipline; Education; Ensure; Evaluation; Fostering; Funding; Goals; Grant; Health; Infrastructure; Institution; Leadership; Logistics; Marketing; Measurement; Measures; Mentorship; Methods; Mission; Play; Principal Investigator; Process; Public Health; Research; Research Contracts; Research Personnel; Research Priority; Research Project Grants; Resource Development; Resources; Robin bird; Role; Science; Scientist; Time; Tobacco; Tobacco Surveillance; Training; U-Series Cooperative Agreements; United States Food and Drug Administration; United States National Institutes of Health; Work; analytical method; career; career development; community engaged research; data sharing; evidence base; experience; innovation; member; programs; response; skills; special interest group; supportive environment; synergism; tobacco products; tobacco regulatory science

PROJECT ABSTRACT Tobacco regulatory science (TRS) provides the evidence base needed to inform the U.S. Food and Drug Administration's (FDA's) regulatory actions and activities. In partnership with the National Institutes of Health (NIH), FDA's Center for Tobacco Products (CTP) established a large, diverse, transdisciplinary research portfolio that aims to advance TRS and generate scientific evidence that FDA CTP can use to inform tobacco regulatory decision-making and protect public health. Additional TRS research is needed to address the ongoing changes in the tobacco product landscape and to continue to understand the health effects and related behaviors of the full complement of tobacco products. A strong and experienced coordinating center will help ensure maximum achievement of these goals by providing scientific leadership and analytic expertise to the research community; bringing researchers together to share methods, measures, data, and findings; providing resources and infrastructure to facilitate collaboration; support TRS career development; and disseminate research findings and relevant resources to the TRS community. The coordinating center will serve as the hub to effectively and efficiently accelerate the impact of research from the TRS community. Through this renewal application to serve as the Center for Coordination of Analysis, Science, Enhancement and Logistics (CASEL), the Westat team proposes to build on our existing infrastructure, approaches, experience and relationships to support the TRS research community and its Federal partners. Our specific aims are to: (1) m aintain a dynamic central hub that supports effective and coordinated collaboration and engagement across the TRS community, NIH, and CTP partners; create synergies and provide valuable resources to advance and accelerate timely high impact research ; (2) provide a robust logistical and management infrastructure within a strong leadership framework for meaningful coordination of the large and diverse portfolio of TRS research; (3) provide scientific leadership and facilitate timely responsiveness to regulatory scientific priorities; (4) coordinate career enhancement activities across the CTP-funded research community that increases research capacity and dissemination, provides mentorship and leadership opportunities for early career scientists, facilitates education in diverse disciplines in TRS, and offers networking and professional development resources; and (5) disseminate research resources to the TRS community through multiple channels, synthesize research findings across the community, provide opportunities to highlight emerging research findings, and coordinate information sharing to accelerate TRS. We are prepared to step into CASEL 2.0 seamlessly, to enhance and expand our initiatives, and to introduce nuanced, engaging innovation in our approaches. Our MPIs, Ms. Jeanne Rosenthal and Dr. Robin Mermelstein have both served effectively in their respective senior management and scientific leadership roles and will continue to oversee the work on the center, along with Core Leads, Dr. Cassandra Stanton and Dr. Andrea Stroup and Program Manager, Ms. Miriam Galbraith. These leaders and our knowledgeable scientific and administrative staff will work together to create a strong and supportive environment to foster and promote the conduct of high quality TRS.

项目摘要 烟草监管科学（TRS）为美国食品和药物管理局提供了必要的证据基础。 管理局（FDA）的监管行动和活动。与美国国立卫生研究院合作， (NIH)FDA的烟草制品中心（CTP）建立了一个大型的，多样化的，跨学科的研究 该组合旨在推进TRS并生成FDA CTP可用于告知烟草的科学证据 监管决策和保护公众健康。需要更多的TRS研究来解决 烟草产品格局的持续变化，并继续了解健康影响， 烟草制品的全面补充的相关行为。一个强大而有经验的协调中心 将通过提供科学领导和分析专业知识，帮助确保最大限度地实现这些目标 向研究界提供信息;将研究人员聚集在一起，分享方法、措施、数据和研究结果; 提供资源和基础设施，以促进合作;支持TRS的职业发展;以及 向TRS社区传播研究成果和相关资源。协调中心将 作为中心，有效和高效地加速TRS社区研究的影响。 通过这次更新申请，作为分析，科学，增强协调中心， 和物流（CASEL），Westat团队建议建立在我们现有的基础设施，方法， 经验和关系，以支持TRS研究界及其联邦合作伙伴。我们的具体 目标是：（1）m 保持一个动态的中心枢纽，支持有效和协调的协作， 跨TRS社区，NIH和CTP合作伙伴的参与;创造协同效应并提供有价值的 资源，以推进和加速及时的高影响力研究 （2）提供一个强大的后勤和 在强有力的领导框架内建立管理基础设施， 多样化的TRS研究组合;（3）提供科学领导，并促进及时响应 监管科学优先事项;（4）协调CTP资助的研究中的职业发展活动 社区，提高研究能力和传播，提供指导和领导 为早期职业科学家提供机会，促进TRS不同学科的教育，并提供 网络和专业发展资源;（5）向TRS传播研究资源 通过多种渠道，综合整个社区的研究成果，提供 有机会突出新兴的研究成果，并协调信息共享，以加快TRS。 我们准备无缝地进入CASEL 2.0，以增强和扩展我们的计划，并引入 细致入微，在我们的方法中进行创新。我们的MPI，Jeanne Rosenthal女士和Robin Mermelstein博士 他们都有效地担任了各自的高级管理和科学领导角色， 继续监督中心的工作，沿着的还有核心领导卡桑德拉·斯坦顿博士和安德烈博士 Stroup和项目经理Miriam Galbraith女士。这些领导人和我们知识渊博的科学和 行政人员将共同努力，创造一个强大的和支持性的环境，以促进和促进 进行高质量的TRS。

项目成果

Guidance for Addressing Conflicts, Bias, and Growth in Early Career Tobacco Regulatory Science Training Through Mentorship.

• DOI: 10.1093/ntr/ntad162
• 发表时间: 2024-01-01
• 期刊: NICOTINE & TOBACCO RESEARCH
• 影响因子: 4.7
• 作者: Stroup, Andrea M.;Villanti, Andrea C.;Pfund, Christine;Benjamin, Emelia J.;Denlinger-Apte, Rachel L.;Garcia-Cazarin, Mary L.;Kwan, Jonathan;Stanton, Cassandra A.
• 通讯作者: Stanton, Cassandra A.

Vaping and anime: a growing area of concern.

• DOI: 10.1136/tobaccocontrol-2021-057195
• 发表时间: 2023-11
• 期刊: TOBACCO CONTROL
• 影响因子: 5.2
• 作者: Wipfli, Heather Lynn;Kim, Minji;Vassey, Julia;Stanton, Cassandra
• 通讯作者: Stanton, Cassandra