Center for Coordination of Analysis, Science, Enhancement, and Logistics (CASEL) in Tobacco Regulatory Science

烟草监管科学分析、科学、增强和物流协调中心 (CASEL)

• 批准号: 10662756
• 负责人: Robin J. Mermelstein
• 金额: $ 370.15万
• 依托单位: WESTAT, INC.
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-30 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10662756
• 关键词: Acceleration; Achievement; Address; Adoption; Agreement; Award; Behavior; Centers for Disease Control and Prevention (U.S.); Collaborations; Communities; Complement; Consensus; Data; Decision Making; Development; Directories; Discipline; Education; Ensure; Evaluation; Fostering; Funding; Goals; Grant; Health; Infrastructure; Institution; Leadership; Logistics; Marketing; Measurement; Measures; Mentorship; Methods; Mission; Play; Principal Investigator; Process; Public Health; Research; Research Contracts; Research Personnel; Research Priority; Research Project Grants; Resource Development; Resources; Robin bird; Role; Science; Scientist; Time; Tobacco; Tobacco Surveillance; Training; U-Series Cooperative Agreements; United States Food and Drug Administration; United States National Institutes of Health; Work; analytical method; career; career development; community engaged research; data sharing; evidence base; experience; innovation; member; programs; response; skills; special interest group; supportive environment; synergism; tobacco products; tobacco regulatory science

PROJECT ABSTRACT Tobacco regulatory science (TRS) provides the evidence base needed to inform the U.S. Food and Drug Administration's (FDA's) regulatory actions and activities. In partnership with the National Institutes of Health (NIH), FDA's Center for Tobacco Products (CTP) established a large, diverse, transdisciplinary research portfolio that aims to advance TRS and generate scientific evidence that FDA CTP can use to inform tobacco regulatory decision-making and protect public health. Additional TRS research is needed to address the ongoing changes in the tobacco product landscape and to continue to understand the health effects and related behaviors of the full complement of tobacco products. A strong and experienced coordinating center will help ensure maximum achievement of these goals by providing scientific leadership and analytic expertise to the research community; bringing researchers together to share methods, measures, data, and findings; providing resources and infrastructure to facilitate collaboration; support TRS career development; and disseminate research findings and relevant resources to the TRS community. The coordinating center will serve as the hub to effectively and efficiently accelerate the impact of research from the TRS community. Through this renewal application to serve as the Center for Coordination of Analysis, Science, Enhancement and Logistics (CASEL), the Westat team proposes to build on our existing infrastructure, approaches, experience and relationships to support the TRS research community and its Federal partners. Our specific aims are to: (1) m aintain a dynamic central hub that supports effective and coordinated collaboration and engagement across the TRS community, NIH, and CTP partners; create synergies and provide valuable resources to advance and accelerate timely high impact research ; (2) provide a robust logistical and management infrastructure within a strong leadership framework for meaningful coordination of the large and diverse portfolio of TRS research; (3) provide scientific leadership and facilitate timely responsiveness to regulatory scientific priorities; (4) coordinate career enhancement activities across the CTP-funded research community that increases research capacity and dissemination, provides mentorship and leadership opportunities for early career scientists, facilitates education in diverse disciplines in TRS, and offers networking and professional development resources; and (5) disseminate research resources to the TRS community through multiple channels, synthesize research findings across the community, provide opportunities to highlight emerging research findings, and coordinate information sharing to accelerate TRS. We are prepared to step into CASEL 2.0 seamlessly, to enhance and expand our initiatives, and to introduce nuanced, engaging innovation in our approaches. Our MPIs, Ms. Jeanne Rosenthal and Dr. Robin Mermelstein have both served effectively in their respective senior management and scientific leadership roles and will continue to oversee the work on the center, along with Core Leads, Dr. Cassandra Stanton and Dr. Andrea Stroup and Program Manager, Ms. Miriam Galbraith. These leaders and our knowledgeable scientific and administrative staff will work together to create a strong and supportive environment to foster and promote the conduct of high quality TRS.

项目摘要 烟草监管科学（TRS）提供了通知美国食品和药物的证据基础 政府（FDA）的监管行动和活动。与美国国立卫生研究院合作 （NIH）FDA的烟草产品中心（CTP）建立了一项大型，多样的跨学科研究 旨在提高TRS并生成科学证据表明FDA CTP可以用来通知烟草的投资组合 监管决策并保护公共卫生。需要其他TRS研究来解决 烟草产品景观的持续变化，并继续了解健康影响和 烟草产品完整补充的相关行为。一个强大而经验丰富的协调中心 通过提供科学领导和分析专业知识，将有助于确保这些目标的最大成就 去研究界；将研究人员聚集在一起，共享方法，措施，数据和发现； 提供资源和基础设施以促进协作；支持TRS职业发展；和 向TRS社区传播研究发现和相关资源。协调中心将 充当有效有效地加速TRS社区研究影响的枢纽。 通过这种续签应用，作为分析，科学，增强的协调中心 和物流（CASEL），Westat团队建议以我们现有的基础设施为基础 支持TRS研究社区及其联邦合作伙伴的经验和关系。我们的具体 目的是：（1）M Aintain一个动态的中央枢纽，支持有效和协调的协作和 在TRS社区，NIH和CTP合作伙伴之间的参与；创造协同作用并提供有价值的 推进和加速及时高影响研究的资源 ; （2）提供强大的后勤和 在强大的领导框架内管理基础架构，以实现大型和大型协调 TRS研究的多样化组合； （3）提供科学领导并促进及时的响应能力 监管科学重点； （4）协调CTP资助的研究的职业增强活动 提高研究能力和传播，提供指导和领导才能的社区 早期职业科学家的机会，促进TRS中各种学科的教育，并提供 网络和专业发展资源； （5）向TRS传播研究资源 通过多个渠道社区，整个社区的研究结果，提供 强调新兴的研究结果并协调信息共享以加速TRS的机会。 我们准备无缝进入Casel 2.0，以增强和扩展我们的计划，并介绍 在我们的方法中细微，引人入胜的创新。我们的MPIS，Jeanne Rosenthal女士和Robin Mermelstein博士 两者都在各自的高级管理和科学领导角色中有效任职，并将 继续监督中心的工作，以及Core Leads，Cassandra Stanton博士和Andrea博士 Stroup兼项目经理Miriam Galbraith女士。这些领导者和我们知识渊博的科学和 行政人员将共同努力创造一个强大而支持的环境，以促进和促进 高质量TR的行为。

项目成果

Guidance for Addressing Conflicts, Bias, and Growth in Early Career Tobacco Regulatory Science Training Through Mentorship.

• DOI: 10.1093/ntr/ntad162
• 发表时间: 2024-01-01
• 期刊: NICOTINE & TOBACCO RESEARCH
• 影响因子: 4.7
• 作者: Stroup, Andrea M.;Villanti, Andrea C.;Pfund, Christine;Benjamin, Emelia J.;Denlinger-Apte, Rachel L.;Garcia-Cazarin, Mary L.;Kwan, Jonathan;Stanton, Cassandra A.
• 通讯作者: Stanton, Cassandra A.

Vaping and anime: a growing area of concern.

• DOI: 10.1136/tobaccocontrol-2021-057195
• 发表时间: 2023-11
• 期刊: TOBACCO CONTROL
• 影响因子: 5.2
• 作者: Wipfli, Heather Lynn;Kim, Minji;Vassey, Julia;Stanton, Cassandra
• 通讯作者: Stanton, Cassandra