NorthStar Node of the Clinical Trials Network: Facebook intervention for preventing opioid relapse among American Indian Women

项目总结 2017年，明尼苏达州(MN)的美国印第安人和阿拉斯加原住民(AIAN)成年人患癌症的可能性是美国人的六倍 死于过量的阿片类药物而不是白人，这是AIAN之间观察到的最大差异 以及美国的白人。阿片使用障碍的药物治疗(MOUD)是一种循证的方法，并且 促进持续药物治疗和支持乌德康复的策略很重要。性别- 影响阿片类药物使用、复发和康复的特定因素，与 男性包括感受到的压力、创伤和对节欲的社会支持。AIAN针对性别的干预措施 因为我们并不存在。研究记录了社交网络和社会支持对以下方面的积极影响 戒除物质使用。然而，了解如何最好地利用社会支持仍然是关键 对上瘾治疗领域的挑战。我们建议通过开发社交数字来解决这些差距 (Facebook)干预以促进阿片类药物戒断的压力管理和社交网络支持 在AIAN女性中。虚拟数字平台具有扩大覆盖范围和扩大规模的潜力。与 AIAN相互依赖的文化价值，社交媒体形成的防止阿片类药物复发的团体可能会导致 通过鼓励AIAN几代妇女之间的合作努力，提高收养和可持续性 并利用社区的韧性来应对压力。这一为期一年的第一阶段试点的总体目标是 预备研究是开发和贝塔测试Facebook干预措施，以减少AIAN中的阿片类药物复发 女人。该项目是与MN印度妇女资源中心的社区合作伙伴共同设计的 (MIWRC)。一个专门研究的社区咨询委员会将指导所有项目活动。其具体目的是 开发并对Facebook干预内容和原型进行Beta测试。在这次形成性工作中，我们将进行 通过电话/视频对AIAN有OUD的妇女进行个别定性访谈， 戒毒至少一个月并接受Moud(n=12)；以及成瘾护理提供者和 AIAN社区利益相关者(n=12)。参与者将提供关于文化相关性和感知的信息 干预内容的有效性。将开发一个Facebook干预原型，并进行Beta测试，以及 与AIAN妇女反复精炼(n=10)。 结果将为未来干预的试点随机对照试验的发展提供信息。这个项目是 创新地开发了一种针对性别的、基于社会的、阿片类药物复发预防干预措施 与文化相关并已被采用的媒体技术。这项概念验证研究是第一次 采取一种干预措施，最终可能通过成瘾保健和 以社区为基础的环境以及社交媒体；并作为开发社交数字的典范 在其他人群中进行成瘾治疗，提高整体覆盖面和影响力。

PROJECT SUMMARY In 2017, American Indian and Alaska Native (AIAN) adults in Minnesota (MN) were six times more likely to die of an overdose involving opioids than whites, representing the greatest disparity observed between AIAN and whites in the US. Medication for opioid use disorder (MOUD) is an evidence-based approach, and strategies to promote continuation of pharmacotherapy and support OUD recovery are important. Gender- specific factors affecting opioid use relapse and recovery that are more prevalent in women compared with men include perceived stress, trauma, and social support for abstinence. AIAN gender-specific interventions for OUD do not exist. Research has documented the positive impact of social networks and social support on abstinence from substance use. However, understanding how best to leverage social support remains a key challenge for the addiction’s treatment field. We propose to address these gaps by developing a social digital (Facebook) intervention to promote stress management and social network support for opioid abstinence among AIAN women. Virtual digital platforms have potential for greater reach and scale. Consistent with the AIAN cultural value of interdependence, social media-formed groups to prevent opioid relapse could lead to greater adoption and sustainability by encouraging collaborative efforts across generations of AIAN women and leveraging community resilience for coping with stress. The overall objective of this one-year, Phase I, pilot preparatory study is to develop and beta-test a Facebook intervention for reducing opioid relapse among AIAN women. This project was designed with community partners at the MN Indian Women’s Resource Center (MIWRC). A study-specific community advisory committee will guide all project activities. The Specific Aim is to develop and beta-test the Facebook intervention content and prototype. In this formative work, we will conduct individual qualitative interviews by phone/video with a purposefully recruited sample of AIAN women with OUD, with at least one month of abstinence and receiving MOUD (n=12); as well as addiction care providers and AIAN community stakeholders (n=12). Participants will provide input on the cultural relevance and perceived effectiveness of intervention content. A Facebook intervention prototype will be developed, beta-tested, and iteratively refined with AIAN women (n=10). Results will inform development of a future pilot randomized control trial of the intervention. This project is innovative for developing a gender-specific, socially based, opioid relapse prevention intervention using social media technologies that are culturally relevant and already adopted. This proof-of-concept study is the first step to an intervention that could ultimately be widely disseminated through addiction health care and community-based settings as well as social media; and serve as a model for developing social digital addictions treatment in other populations, enhancing overall reach and impact.