NorthStar Node of the Clinical Trials Network: Facebook intervention for preventing opioid relapse among American Indian Women

项目摘要 2017年，明尼苏达州（MN）的美国印第安人和阿拉斯加原住民（AIAN）成年人有六倍的可能性 死于阿片类药物过量的人比白人多，这代表了AIAN之间观察到的最大差异。 白人在美国。阿片类药物使用障碍（MOUD）是一种循证方法， 促进持续药物治疗和支持OUD恢复的策略是重要的。性别- 影响阿片类药物使用复发和康复的具体因素，与 男性包括感受到的压力、创伤和禁欲的社会支持。AIAN针对性别的干预措施 OUD不存在。研究证明，社交网络和社会支持对 对物质使用的节制。然而，了解如何最好地利用社会支持仍然是一个关键， 成瘾治疗领域的挑战。我们建议通过开发一个社交数字平台来解决这些差距。 （Facebook）干预，以促进压力管理和社交网络支持阿片类药物戒断 在女性中。虚拟数字平台具有扩大覆盖面和规模的潜力。符合 AIAN文化价值的相互依存，社会媒体形成的群体，以防止阿片类药物复吸可能导致 通过鼓励跨代AIAN妇女的合作努力，提高采用率和可持续性 以及利用社区弹性来应对压力。这一为期一年的第一阶段试点项目的总体目标是 一项预备性研究是开发和测试Facebook干预措施，以减少AIAN中的阿片类药物复发 妇女该项目是与MN印第安妇女资源中心的社区合作伙伴共同设计的 （MIWRC）。一个专门研究的社区咨询委员会将指导所有项目活动。具体目标是 开发和测试Facebook干预内容和原型。在这项工作中，我们将进行 通过电话/视频对有目的地招募的AIAN女性OUD样本进行个人定性访谈， 至少有一个月的禁欲和接受MOUD（n = 12）;以及成瘾护理提供者， AIAN社区利益攸关方（n = 12）。与会者将提供关于文化相关性和感知的投入 干预内容的有效性。将开发Facebook干预原型，进行beta测试， 用AIAN女性（n = 10）迭代细化。 研究结果将为未来的干预措施的试点随机对照试验提供信息。这个项目是 创新性地开发了一种基于社会的、针对性别的阿片类药物复吸预防干预措施， 与文化相关并已被采用的媒体技术。这项概念验证研究是第一个 逐步采取干预措施，最终可以通过成瘾卫生保健和 以社区为基础的环境以及社交媒体;并作为发展社交数字化的典范 在其他人群中进行成瘾治疗，提高整体覆盖面和影响力。

PROJECT SUMMARY In 2017, American Indian and Alaska Native (AIAN) adults in Minnesota (MN) were six times more likely to die of an overdose involving opioids than whites, representing the greatest disparity observed between AIAN and whites in the US. Medication for opioid use disorder (MOUD) is an evidence-based approach, and strategies to promote continuation of pharmacotherapy and support OUD recovery are important. Gender- specific factors affecting opioid use relapse and recovery that are more prevalent in women compared with men include perceived stress, trauma, and social support for abstinence. AIAN gender-specific interventions for OUD do not exist. Research has documented the positive impact of social networks and social support on abstinence from substance use. However, understanding how best to leverage social support remains a key challenge for the addiction’s treatment field. We propose to address these gaps by developing a social digital (Facebook) intervention to promote stress management and social network support for opioid abstinence among AIAN women. Virtual digital platforms have potential for greater reach and scale. Consistent with the AIAN cultural value of interdependence, social media-formed groups to prevent opioid relapse could lead to greater adoption and sustainability by encouraging collaborative efforts across generations of AIAN women and leveraging community resilience for coping with stress. The overall objective of this one-year, Phase I, pilot preparatory study is to develop and beta-test a Facebook intervention for reducing opioid relapse among AIAN women. This project was designed with community partners at the MN Indian Women’s Resource Center (MIWRC). A study-specific community advisory committee will guide all project activities. The Specific Aim is to develop and beta-test the Facebook intervention content and prototype. In this formative work, we will conduct individual qualitative interviews by phone/video with a purposefully recruited sample of AIAN women with OUD, with at least one month of abstinence and receiving MOUD (n=12); as well as addiction care providers and AIAN community stakeholders (n=12). Participants will provide input on the cultural relevance and perceived effectiveness of intervention content. A Facebook intervention prototype will be developed, beta-tested, and iteratively refined with AIAN women (n=10). Results will inform development of a future pilot randomized control trial of the intervention. This project is innovative for developing a gender-specific, socially based, opioid relapse prevention intervention using social media technologies that are culturally relevant and already adopted. This proof-of-concept study is the first step to an intervention that could ultimately be widely disseminated through addiction health care and community-based settings as well as social media; and serve as a model for developing social digital addictions treatment in other populations, enhancing overall reach and impact.