NorthStar Node of the Clinical Trials Network

项目摘要：物质使用障碍(SUD)是造成全球疾病负担的重要因素。 酒精、烟草和其他毒品每年的直接和间接经济成本估计为500美元。 仅在美国就有10亿美元。据估计，目前有2020万美国人需要治疗sod。 只有不到5%的人接受了特殊治疗。美国最频繁的医疗保健接触点 是门诊初级护理。明尼苏达州的健康状况在美国排名第一，是美国健康状况最高的州之一 在美国获得初级保健的机会。建议的NIDA临床试验网络的NorthStar节点带来了 将各种医疗保健提供模式结合在一起，在初级保健的提供和研究方面表现出色。由内部领导 在上瘾方面具有实践和研究专长的医学医生，北极星节点包括：1)两个 主要的非营利性综合卫生系统，通过100多个初选为100多万明尼苏达州人提供服务 护理诊所(HealthPartners和Allina Health)；2)联邦合格的健康中心(Northpoint Health& 健康中心)；3)负责管理最贫穷和最高医疗保健利用率的医疗保健组织 明尼苏达州人口最多的县(亨内平健康中心)的人口；4)学生健康中心，它 为20,000多名大学生提供初级和行为护理(明尼苏达大学 Boynton Health Services)；5)临床系统改进研究所(ICSI)，一个非营利性健康机构 致力于开发和实施质量改进和最佳实践的改进组织 超过45个医疗系统和8,000名医生的协议；以及6)明尼苏达大学 临床与翻译科学研究所。在完成CTN任务时，北极星节点将开发 (1)SUD患者慢性护理疾病协调管理模式；(2)风险分层工具 初级保健中用于慢性疼痛管理的阿片类处方，(3)临床决策支持工具 关于阿片类药物使用障碍的治疗，(4)戒烟治疗和艾滋病毒初级治疗的综合模式 护理，以及(5)有效的模式，以降低出院的SUD患者或高危用户的30天再住院率 从住院的普通医疗机构。

Project summary: Substance use disorders (SUD) are significant contributors to the global burden of disease. Annual direct and indirect economic costs of alcohol, tobacco, and other drugs have been estimated at $500 billion in the United States alone. An estimated 20.2 million Americans are in need of treatment for a SUD, yet fewer than 5% receive specialty treatment. The most frequent point of health care contact in the United States is outpatient primary care. Minnesota ranks 1st in the US for health status and has one of the highest rates of access to primary care in the US. The proposed NorthStar node of the NIDA Clinical Trials Network brings together diverse healthcare delivery models that excel in delivery and research of primary care. Led by internal medicine physicians with practice and research expertise in addiction, the NorthStar node includes: 1) two major non-profit integrated health systems serving more than 1 million Minnesotans through over 100 primary care clinics (HealthPartners and Allina Health); 2) a Federally Qualified Health Center (NorthPoint Health & Wellness Center); 3) an accountable care organization managing the poorest and highest healthcare utilizing populations of Minnesota's most populous county (Hennepin Health); 4) a student health center, which provides primary and behavioral care for the more than 20,000 university students (University of Minnesota's Boynton Health Services); 5) the Institute for Clinical Systems Improvement (ICSI), a non-profit health improvement organization dedicated to developing and implementing quality improvement and best-practices protocols across more than 45 health systems and 8,000 physicians; and 6) the University of Minnesota Clinical and Translational Sciences Institute. In fulfillment of the CTN mission, the NorthStar node will develop (1) models of coordinated chronic care disease management of patients with SUD, (2) risk stratification tools for opiate prescription for chronic pain management in primary care, (3) clinical decision support tools focusing on the treatment of opiate use disorders, (4) integrated models of tobacco cessation treatment and HIV primary care, and (5) effective models to reduce 30-day readmission rates for SUD patients or at-risk users discharged from inpatient general medical settings.