LA CaTS Supplement NOT-OD-21-101

LA CatS 补充剂 NOT-OD-21-101

• 批准号: 10403313
• 负责人: JOHN P. KIRWAN
• 金额: $ 30万
• 依托单位: LSU PENNINGTON BIOMEDICAL RESEARCH CTR
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-15 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10403313
• 关键词: 16 year old; 2019-nCoV; Achievement; Address; Administrative Supplement; Adult; African American; Award; Biomedical Research; COVID-19; COVID-19 pandemic; COVID-19 testing; COVID-19 vaccination; COVID-19 vaccine; Center for Translational Science Activities; Chronic; Church; Cities; Clinic; Clinical Sciences; Communities; Consultations; Control Groups; Counseling; Development; Diabetes Mellitus; Dose; Environment; Epidemic; Event; Family; Focus Groups; Foundations; Funding; Goals; Health; Health Status; Hypertension; Infrastructure; Institutional Review Boards; Intervention; Knowledge; Lead; Louisiana; Low income; Measures; Methods; Minority Groups; Multimedia; Obesity; Outcome; Participant; Phase; Population; Positioning Attribute; Premature Mortality; Provider; Questionnaires; RADx Underserved Populations; Randomized; Reporting; Research Design; Research Project Grants; Resources; Safety; Sampling; Schools; Site; Societies; Source; South American; Structure; Testing; Training; Translational Research; Trust; Underserved Population; United States; United States National Institutes of Health; Urban Community; Ursidae Family; Vaccinated; Vaccines; Work; base; community center; community engaged research; community engagement; comorbidity; effectiveness evaluation; group intervention; health disparity; health economics; improved; intervention effect; low socioeconomic status; member; mortality; primary outcome; programs; randomized trial; response; side effect; testing uptake; trial design; urban underserved; vaccine acceptance; vaccine access; vaccine hesitancy

Project Summary/Abstract In the US, COVID-19 unveiled a disproportionate health burden in low income and underserved segments of society. In Louisiana, some of the greatest health and economic consequences are evident in our Black communities. Furthermore, despite the widespread availability of SARS-CoV-2 vaccines, approximately 30% of the US population reports that they will not get vaccinated, and Black citizens and those with lower socio- economic status are more likely to have vaccine hesitancy. Thus, there is an urgent need to address vaccine hesitancy within the context of the COVID-19 pandemic and the current testing environment. The Louisiana Clinical and Translational Science (LA CaTS) Center provides the essential infrastructure and key foundational support for biomedical research in our region and is uniquely positioned to lead a community-engaged research project to determine solutions to decrease vaccine hesitancy and improve testing rates in our most underserved populations. Faith-based organizations (churches, mosques, temples, etc.) are trusted sources of information, especially among Black communities, and may represent an opportunity to convey accurate, unbiased health information regarding COVID-19 vaccinations and testing to the community. Many Black churches have well-developed health ministries that integrate faith and health for their members and the communities they serve. We will use a mixed-methods study design to determine the effectiveness of training church health ministers to educate their congregations about the safety and efficacy of COVID-19 vaccines for decreasing vaccine hesitancy and improving testing knowledge in underserved Black communities. We will randomize 98 participants from five churches to an intervention group that will receive counseling from their health ministers on the benefits of getting vaccinated and tested, or to a delayed intervention control group. The effects of the intervention on the primary outcome, vaccine hesitancy measured by a structured questionnaire, will be studied after three weeks. Following the three-week control period, the delayed intervention control group will also receive the intervention. We will then conduct focus groups among a sub-sample of participants to obtain more granular information on sources of vaccine hesitancy and for their vaccine-related decisions. The achievement of the study's goals will significantly increase our understanding of vaccine hesitancy within Black urban communities in Louisiana. Our results will inform the development of targeted interventions to increase vaccine coverage in the large, underserved populations across the American South.

项目摘要/摘要 在美国，Covid-19揭示了低收入的不成比例的健康负担，并且服务不足 社会。在路易斯安那州，我们的黑人有一些最大的健康和经济后果很明显 社区。此外，尽管SARS-COV-2疫苗广泛可用，但约有30％ 美国人口报告说，他们不会接种疫苗，黑人公民和社会社会较低的人 - 经济状况更有可能有疫苗犹豫。因此，迫切需要解决疫苗 在COVID-19大流行和当前的测试环境的背景下犹豫。路易斯安那州 临床和转化科学（LA CATS）中心提供了必不可少的基础设施和关键基础 支持我们地区的生物医学研究，并具有独特的位置，可以领导社区参与 研究项目以确定解决方案以减少疫苗犹豫不决并提高我们最大的测试率 服务不足的人群。基于信仰的组织（教堂，清真寺，庙宇等）是可信赖的来源 信息，尤其是黑人社区中的信息，可能代表传达准确的机会， 关于COVID-19-19的疫苗接种和对社区测试的无偏健康信息。许多黑色 教会拥有完善的卫生部，将信仰和健康整合给其成员和健康部 他们服务的社区。我们将使用混合方法研究设计来确定 培训教会卫生部长，以教育他们的会众有关的安全性和功效 COVID-19疫苗可减少疫苗犹豫不决并改善服务不足的测试知识 黑人社区。我们将将98名参与者从五个教堂到一个干预小组，将 从其卫生部长那里获得有关接种疫苗和测试的好处或延迟的咨询 干预对照组。干预对主要结局的影响，疫苗犹豫不决 由结构化的问卷调查，将在三个星期后研究。在三周的控制期之后， 延迟干预对照组也将接受干预。然后，我们将在 参与者的子样本，以获取有关疫苗犹豫不决及其疫苗来源的更多详细信息 与疫苗有关的决定。研究目标的实现将大大提高我们对 路易斯安那州黑人城市社区内的疫苗犹豫。我们的结果将为发展 有针对性的干预措施，以增加美国跨美国服务不足的人口的疫苗覆盖率 南。