LA CaTS Supplement NOT-OD-21-101

LA CatS 补充剂 NOT-OD-21-101

• 批准号: 10403313
• 负责人: JOHN P. KIRWAN
• 金额: $ 30万
• 依托单位: LSU PENNINGTON BIOMEDICAL RESEARCH CTR
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-15 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10403313
• 关键词: 16 year old; 2019-nCoV; Achievement; Address; Administrative Supplement; Adult; African American; Award; Biomedical Research; COVID-19; COVID-19 pandemic; COVID-19 testing; COVID-19 vaccination; COVID-19 vaccine; Center for Translational Science Activities; Chronic; Church; Cities; Clinic; Clinical Sciences; Communities; Consultations; Control Groups; Counseling; Development; Diabetes Mellitus; Dose; Environment; Epidemic; Event; Family; Focus Groups; Foundations; Funding; Goals; Health; Health Status; Hypertension; Infrastructure; Institutional Review Boards; Intervention; Knowledge; Lead; Louisiana; Low income; Measures; Methods; Minority Groups; Multimedia; Obesity; Outcome; Participant; Phase; Population; Positioning Attribute; Premature Mortality; Provider; Questionnaires; RADx Underserved Populations; Randomized; Reporting; Research Design; Research Project Grants; Resources; Safety; Sampling; Schools; Site; Societies; Source; South American; Structure; Testing; Training; Translational Research; Trust; Underserved Population; United States; United States National Institutes of Health; Urban Community; Ursidae Family; Vaccinated; Vaccines; Work; base; community center; community engaged research; community engagement; comorbidity; effectiveness evaluation; group intervention; health disparity; health economics; improved; intervention effect; low socioeconomic status; member; mortality; primary outcome; programs; randomized trial; response; side effect; testing uptake; trial design; urban underserved; vaccine acceptance; vaccine access; vaccine hesitancy

Project Summary/Abstract In the US, COVID-19 unveiled a disproportionate health burden in low income and underserved segments of society. In Louisiana, some of the greatest health and economic consequences are evident in our Black communities. Furthermore, despite the widespread availability of SARS-CoV-2 vaccines, approximately 30% of the US population reports that they will not get vaccinated, and Black citizens and those with lower socio- economic status are more likely to have vaccine hesitancy. Thus, there is an urgent need to address vaccine hesitancy within the context of the COVID-19 pandemic and the current testing environment. The Louisiana Clinical and Translational Science (LA CaTS) Center provides the essential infrastructure and key foundational support for biomedical research in our region and is uniquely positioned to lead a community-engaged research project to determine solutions to decrease vaccine hesitancy and improve testing rates in our most underserved populations. Faith-based organizations (churches, mosques, temples, etc.) are trusted sources of information, especially among Black communities, and may represent an opportunity to convey accurate, unbiased health information regarding COVID-19 vaccinations and testing to the community. Many Black churches have well-developed health ministries that integrate faith and health for their members and the communities they serve. We will use a mixed-methods study design to determine the effectiveness of training church health ministers to educate their congregations about the safety and efficacy of COVID-19 vaccines for decreasing vaccine hesitancy and improving testing knowledge in underserved Black communities. We will randomize 98 participants from five churches to an intervention group that will receive counseling from their health ministers on the benefits of getting vaccinated and tested, or to a delayed intervention control group. The effects of the intervention on the primary outcome, vaccine hesitancy measured by a structured questionnaire, will be studied after three weeks. Following the three-week control period, the delayed intervention control group will also receive the intervention. We will then conduct focus groups among a sub-sample of participants to obtain more granular information on sources of vaccine hesitancy and for their vaccine-related decisions. The achievement of the study's goals will significantly increase our understanding of vaccine hesitancy within Black urban communities in Louisiana. Our results will inform the development of targeted interventions to increase vaccine coverage in the large, underserved populations across the American South.

项目概要/摘要 在美国，COVID-19 给低收入和服务不足的人群带来了不成比例的健康负担 社会。在路易斯安那州，一些最严重的健康和经济后果在我们的黑人中显而易见 社区。此外，尽管 SARS-CoV-2 疫苗已广泛使用，但仍有约 30% 的人接种了疫苗。 美国民众报告说他们不会接种疫苗，黑人公民和社会地位较低的人 经济状况更容易对疫苗产生犹豫。因此，迫切需要解决疫苗问题 在 COVID-19 大流行和当前测试环境的背景下犹豫不决。路易斯安那号 临床和转化科学 (LA CatS) 中心提供必要的基础设施和关键基础 支持我们地区的生物医学研究，并处于领导社区参与的独特地位 研究项目旨在确定减少疫苗犹豫并提高大多数国家检测率的解决方案 服务不足的人群。基于信仰的组织（教堂、清真寺、寺庙等）是值得信赖的来源 信息，特别是在黑人社区中，并且可能代表一个传达准确、 向社区提供有关 COVID-19 疫苗接种和检测的公正健康信息。许多黑色 教会拥有完善的卫生部门，将其成员和信徒的信仰与健康融为一体。 他们所服务的社区。我们将使用混合方法研究设计来确定以下方法的有效性： 培训教会卫生部长，让他们的会众了解医疗保健的安全性和有效性 COVID-19 疫苗可减少服务不足地区的疫苗犹豫并提高检测知识 黑人社区。我们将把来自 5 个教会的 98 名参与者随机分配到一个干预组，该组将 接受卫生部长关于接种疫苗和检测的好处的咨询，或延迟接种 干预对照组。干预措施对主要结果（测量的疫苗犹豫度）的影响 通过结构化问卷，将在三周后进行研究。经过三周的控制期后， 延迟干预对照组也将接受干预。然后我们将在其中开展焦点小组 参与者的子样本，以获得有关疫苗犹豫的来源和他们的疫苗的更详细信息 疫苗相关的决定。研究目标的实现将显着增加我们对 路易斯安那州黑人城市社区对疫苗犹豫不决。我们的结果将为以下领域的发展提供信息 有针对性的干预措施，以提高美国大量服务不足的人群的疫苗覆盖率 南。