Louisiana Clinical and Translational Science Center

路易斯安那州临床和转化科学中心

• 批准号: 10677678
• 负责人: JOHN P. KIRWAN
• 金额: $ 400万
• 依托单位: LSU PENNINGTON BIOMEDICAL RESEARCH CTR
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-15 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10677678
• 关键词: Academic Medical Centers; Address; Administrative Supplement; Advisory Committees; Applications Grants; Area; Award; Bioinformatics; Biomedical Research; Biometry; Black race; COVID testing; COVID-19; COVID-19 pandemic; COVID-19 patient; COVID-19 testing; COVID-19 vaccination; Cardiovascular Diseases; Center for Translational Science Activities; Chronic Disease; Clinic; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Collaborations; Communication; Communities; Dedications; Development; Diabetes Mellitus; Disease Management; Disparity; Diverse Workforce; Education; Ensure; Federally Qualified Health Center; Funding; Generations; Goals; Grant; Growth; Health; Health Sciences; Healthcare; Healthcare Systems; Hurricane; Infrastructure; Inosine Dialdehyde; Institution; Institutional Review Boards; Investments; Learning; Long COVID; Longterm Follow-up; Louisiana; Malignant Neoplasms; Mission; Modeling; Obesity; Outcome; Patients; Pediatric Hospitals; Persons; Positioning Attribute; Post-Acute Sequelae of SARS-CoV-2 Infection; Productivity; Professional Education; Provider; Public Health; Publications; RADx Underserved Populations; Research; Research Infrastructure; Research Personnel; Resources; Role; Rural; Scholars Program; School Dentistry; Scientist; Services; Structure; System; Teacher Professional Development; Testing; Time; Training; Translational Research; Trust; Underrepresented Minority; Underserved Population; United States National Institutes of Health; Universities; Vaccination; Veterans; Work; clinical translation; cohort; community engagement; coronavirus disease; diversity and inclusion; experience; health disparity; health equity; health literacy; high risk population; improved; investigator training; minority communities; mortality; multidisciplinary; operation; pandemic disease; precision medicine; precision nutrition; pressure; programs; recoverin protein; recruit; resilience; response; rural health clinic; safety net; skills; social health determinants; synergism; underserved community; virtual platform

Project Summary: Overall The Louisiana Clinical and Translational Science (LA CaTS) Center is a consortium of the major academic and biomedical research centers in the State of Louisiana. Pennington Biomedical Research Center is the lead institution and will continue to partner with Louisiana State University Health (LSUH)-New Orleans and Tulane University Health Sciences Center in this initiative. LSUH-Shreveport, LSU-A&M (Baton Rouge), Xavier University and Children's Hospital New Orleans, were early Research Partners in cycle 1. Southeast Louisiana Veterans Healthcare System, a newly opened University Medical Center in New Orleans ($1 billion State investment), Ochsner Health and the LSUH-NO School of Dentistry joined during cycle 2. The LA CaTS Center is growing a unified clinical translational science program for Louisiana based on the creation of synergistic programs and unparalleled collaboration from all the major academic and biomedical research institutions in the state. Since inception 9 years ago, the LA CaTS Center has: 1) successfully leveraged resources and expertise of multiple participating institutions to build a vibrant statewide research infrastructure; 2) developed highly synergistic and integrative collaborative programs; 3) implemented a systematic approach to clinical research across all institutions, that includes a new SMART IRB Reliance Model review; and 4) implemented a highly effective governance system based on an unprecedented level of trust between partners. LA CaTS is experiencing exponential growth in research productivity as assessed by key metrics including a three-fold increase in external grant awards, a more than two-fold increase in publications with authors acknowledging LA CaTS Center resources and services and over 600 researchers benefiting from and using our services. Notably, during a period that has been marked by unique and unprecedented challenges from COVID and then Hurricane Ida, LA CaTS has achieved, and in many cases exceeded, its stated objectives and projected milestones. Indeed, since the COVID pandemic hit Louisiana in March of 2020, LA CaTS has led multiple successful grant applications for Administrative Supplements and NOSI awards, notably to facilitate COVID testing and vaccinations in underserved Black communities through the RADx-UP program and most recently our partnership with the IDeA state ISCORE consortium on the national Long-COVID initiative - Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)/RECOVER trial. However, we fully recognize that our work has only just begun, as we collectively address disparities and improve the lives of our citizens. It is also apparent, that slowly, but surely, we are impacting public health one project at a time! With new services proposed and the additional resources that will be added, our Center is uniquely positioned to devote our activities and resources to our major theme for the next 5-year cycle that will “address health disparities and improve the health outcomes of the citizens we serve”.

项目概要：总体 路易斯安那州临床和转化科学中心（LA CaTS）是一个由主要学术机构组成的联盟。 以及路易斯安那州的生物医学研究中心彭宁顿生物医学研究中心是 该机构并将继续与路易斯安那州立大学健康（LSUH）-新奥尔良和杜兰合作 大学健康科学中心在这一倡议。LSUH-Shreveport，LSU-A&M（巴吞鲁日），泽维尔 新奥尔良大学和儿童医院是第一周期的早期研究合作伙伴。路易斯安那州东南 退伍军人医疗保健系统，一个新开设的大学医疗中心在新奥尔良（10亿美元的国家 投资），Ochsner Health和LSUH-NO牙科学院在第2周期加入。LA CATS中心 正在为路易斯安那州建立一个统一的临床转化科学计划， 计划和无与伦比的合作，从所有主要的学术和生物医学研究机构在 状态自9年前成立以来，洛杉矶CaTS中心已：1）成功地利用资源和专业知识 多个参与机构建立一个充满活力的全州研究基础设施; 2）高度发展 协同和整合的合作计划; 3）实施系统的临床研究方法 在所有机构中，这包括一个新的SMART IRB依赖模型审查;和4）实施了一个高度 有效的治理体系建立在合作伙伴之间前所未有的信任基础上。洛杉矶猫 通过关键指标评估，研究生产力呈指数级增长，包括三倍的 外部赠款奖励增加，作者承认LA的出版物增加了两倍多 CaTS中心的资源和服务以及600多名研究人员受益于并使用我们的服务。值得注意的是， 在这段时期，新冠肺炎和飓风带来了前所未有的独特挑战， 艾达，洛杉矶CaTS已经实现，并在许多情况下超过，其既定的目标和预计的里程碑。 事实上，自2020年3月新冠肺炎疫情袭击路易斯安那州以来，LA CaTS已经领导了多项成功的拨款， 申请行政补充和NOSI奖项，特别是为了促进COVID测试， 通过RADx-UP计划在服务不足的黑人社区接种疫苗， 与IDEA州ISCORE联盟就国家长期COVID倡议-急性后遗症建立伙伴关系 SARS-CoV-2感染（PASC）/RECOVER试验。然而，我们充分认识到，我们的工作只是 这一进程始于我们集体解决差距和改善我们公民生活的时候。很明显，慢慢地， 但毫无疑问，我们一个项目一个项目地影响着公共卫生！随着拟议的新服务和 资源，将增加，我们的中心是独特的定位，把我们的活动和资源，我们的主要 下一个五年周期的主题是“解决健康差距， 我们服务的公民”。