UCLA Dentist-Scientist and Oral Health-Researcher Training Program

加州大学洛杉矶分校牙医科学家和口腔健康研究员培训计划

• 批准号: 10414189
• 负责人: Hung Ton-That
• 金额: $ 17.38万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10414189
• 关键词: Area; Basic Science; Biology; Biomedical Engineering; California; Cancer Biology; Clinical Research; Comprehensive Cancer Center; Core Facility; Cryoelectron Microscopy; Dental; Dentists; Doctor of Philosophy; Engineering; Environment; Epigenetic Process; Genomics; Grant; Health; Healthcare; Image; Institutes; Link; Mentors; Microbe; Molecular Biology; Oral; Oral health; Postdoctoral Fellow; Regenerative Medicine; Research; Research Personnel; Research Training; Resources; School Dentistry; Schools; Science; Scientist; Societies; Training; Training Programs; Translational Research; Virulence; cancer stem cell; career; career development; craniofacial; experience; faculty mentor; improved; innovation; malignant mouth neoplasm; medical schools; nanosystems; next generation; novel; post-doctoral training; pre-doctoral; programs; response; stem cells; translational genetics

Contact PD/PI: Ton-That, Hung PROJECT SUMMARY/ABSTRACT In response to PAR-20-056, we propose to reestablish the T90/R90 comprehensive institutional training program at the UCLA School of Dentistry. This application has been built on more than 20 years of our combined research training and career development at UCLA that launched careers of dentist-scientists and oral health-scientists and prepared them for adverse challenges in science, healthcare, and society. The application continues this long-standing tradition and aims to bolster a vigorous and diverse dental, oral and craniofacial research workforce via a rigorous and interdisciplinary training program that offers trainees novel and innovative research training experiences in a highly supportive institutional environment. We have assembled an excellent team of faculty mentors who embody four areas of scientific strengths – (1) Cancer Biology, Oral Cancer & Stem Cells, (2) Craniofacial Biology, Bioengineering & Regenerative Medicine, (3) Microbes – Virulence Mechanisms and Advanced Imaging by CryoEM, and (4) Translational Genetics, Epigenetics, & Genomics. Our interdisciplinary training program links trainees to mentors at the School of Dentistry, School of Medicine, School of Engineering, Jonsson Comprehensive Cancer Center, Molecular Biology Institute, Stem Cell Institute, and California NanoSystem Institute. The integration of these interdepartmental centers and institutes provides a rich training environment with enormous physical resources and centralized core facilities. We offer five training tracks, (i) Dentist-Scientist Trainee Program (dual degree DDS/PhD), (ii) Dentist-PhD Program (predoctoral research training to dentists), (iii) Dentist-Scientists Postdoctoral Fellow (postdoctoral training to dentists), (iv) Predoctoral PhD Trainee (predoctoral training in oral health), and (v) Oral Health Postdoctoral Fellow (postdoctoral training in oral health). Collectively, our proposed training program will train the next generation of dentist-scientists and oral health scientists to conduct basic, translational, and clinical research to improve dental, oral, and craniofacial health. Project Summary/Abstract Page 6 Contact PD/PI: Ton-That, Hung PROJECT NARATIVE This institutional training grant from the UCLA School of Dentistry aims to train the next generation of dentist- scientists and oral health scientists to conduct basic, translational, and clinical research, via a rigorous and interdisciplinary training program, to bolster a vigorous and diverse dental, oral and craniofacial research workforce.

联系PD/PI：Ton-That，Hung 项目总结/摘要 根据PAR-20-056，我们建议重新建立T90/R90综合机构培训 加州大学洛杉矶分校牙科学院的项目。这个应用程序是建立在我们20多年的 结合研究培训和职业发展在加州大学洛杉矶分校，推出了牙医科学家的职业生涯， 口腔健康科学家，并准备他们在科学，医疗保健和社会的不利挑战。的 应用程序延续了这一悠久的传统，旨在支持一个充满活力和多样化的牙科，口腔和 通过严格的跨学科培训计划，为学员提供新颖的颅面研究工作人员 和创新的研究培训经验，在一个高度支持的制度环境。我们有 组建了一支优秀的教师导师团队，他们体现了四个领域的科学优势-（1）癌症 生物学，口腔癌与干细胞，（2）颅面生物学，生物工程与再生医学，（3） 微生物-毒性机制和先进的CryoEM成像，和（4）翻译遗传学， 表观遗传学和基因组学。我们的跨学科培训计划将学员与学校的导师联系起来。 牙科，医学院，工程学院，琼森综合癌症中心，分子 生物研究所、干细胞研究所和加州纳米系统研究所。整合这些 跨部门的中心和研究所提供了丰富的培训环境和巨大的物质资源 集中的核心设施。我们提供五个培训轨道，（i）牙医-科学家培训生计划（双学位 牙科博士/博士），（二）牙医-博士课程（牙医的博士前研究培训），（三）牙医-科学家 博士后研究员（牙医博士后培训），（iv）博士预科生（口腔医学博士预科培训） （v）口腔健康博士后研究员（口腔健康博士后培训）。总体而言，我们提出的 培训计划将培训下一代牙医科学家和口腔健康科学家进行基本， 翻译和临床研究，以改善牙齿，口腔和颅面健康。 项目摘要/摘要第6页 联系PD/PI：Ton-That，Hung 项目简介 加州大学洛杉矶分校牙科学院的这项机构培训补助金旨在培训下一代牙医， 科学家和口腔健康科学家进行基础，转化和临床研究，通过严格的， 跨学科培训计划，以支持一个充满活力和多样化的牙科，口腔和颅面研究 劳动力