UCLA Dentist-Scientist and Oral Health-Researcher Training Program

加州大学洛杉矶分校牙医科学家和口腔健康研究员培训计划

• 批准号: 10655434
• 负责人: Hung Ton-That
• 金额: $ 14.79万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10655434
• 关键词: Area; Basic Science; Biology; Biomedical Engineering; California; Cancer Biology; Clinical Research; Comprehensive Cancer Center; Core Facility; Cryoelectron Microscopy; Dental; Dentists; Doctor of Philosophy; Engineering; Environment; Epigenetic Process; Genomics; Grant; Health; Healthcare; Image; Institution; Link; Mentors; Microbe; Molecular Biology; Oral; Oral health; Postdoctoral Fellow; Regenerative Medicine; Research; Research Personnel; Research Training; Resources; School Dentistry; Schools; Science; Scientist; Societies; Training; Training Programs; Translational Research; Virulence; cancer cell; career; career development; craniofacial; experience; faculty mentor; improved; innovation; malignant mouth neoplasm; medical schools; nanosystems; next generation; novel; post-doctoral training; pre-doctoral; programs; response; stem cells; translational genetics

Contact PD/PI: Ton-That, Hung PROJECT SUMMARY/ABSTRACT In response to PAR-20-056, we propose to reestablish the T90/R90 comprehensive institutional training program at the UCLA School of Dentistry. This application has been built on more than 20 years of our combined research training and career development at UCLA that launched careers of dentist-scientists and oral health-scientists and prepared them for adverse challenges in science, healthcare, and society. The application continues this long-standing tradition and aims to bolster a vigorous and diverse dental, oral and craniofacial research workforce via a rigorous and interdisciplinary training program that offers trainees novel and innovative research training experiences in a highly supportive institutional environment. We have assembled an excellent team of faculty mentors who embody four areas of scientific strengths – (1) Cancer Biology, Oral Cancer & Stem Cells, (2) Craniofacial Biology, Bioengineering & Regenerative Medicine, (3) Microbes – Virulence Mechanisms and Advanced Imaging by CryoEM, and (4) Translational Genetics, Epigenetics, & Genomics. Our interdisciplinary training program links trainees to mentors at the School of Dentistry, School of Medicine, School of Engineering, Jonsson Comprehensive Cancer Center, Molecular Biology Institute, Stem Cell Institute, and California NanoSystem Institute. The integration of these interdepartmental centers and institutes provides a rich training environment with enormous physical resources and centralized core facilities. We offer five training tracks, (i) Dentist-Scientist Trainee Program (dual degree DDS/PhD), (ii) Dentist-PhD Program (predoctoral research training to dentists), (iii) Dentist-Scientists Postdoctoral Fellow (postdoctoral training to dentists), (iv) Predoctoral PhD Trainee (predoctoral training in oral health), and (v) Oral Health Postdoctoral Fellow (postdoctoral training in oral health). Collectively, our proposed training program will train the next generation of dentist-scientists and oral health scientists to conduct basic, translational, and clinical research to improve dental, oral, and craniofacial health. Project Summary/Abstract Page 6 Contact PD/PI: Ton-That, Hung PROJECT NARATIVE This institutional training grant from the UCLA School of Dentistry aims to train the next generation of dentist- scientists and oral health scientists to conduct basic, translational, and clinical research, via a rigorous and interdisciplinary training program, to bolster a vigorous and diverse dental, oral and craniofacial research workforce.

联系 PD/PI：Ton-That, Hung 项目概要/摘要 针对PAR-20-056，我们建议重新建立T90/R90综合机构培训 加州大学洛杉矶分校牙科学院的项目。该应用程序建立在我们 20 多年的经验之上 在加州大学洛杉矶分校将研究培训和职业发展相结合，开启了牙医科学家的职业生涯 口腔健康科学家，让他们做好应对科学、医疗保健和社会方面的不利挑战的准备。这 应用程序延续了这一悠久的传统，旨在促进充满活力和多样化的牙科、口腔和 通过严格的跨学科培训计划培养颅面研究人员，为学员提供新颖的培训 在高度支持的机构环境中获得创新的研究培训经验。我们有 组建了一支优秀的导师团队，他们体现了四个领域的科学优势 – (1) 癌症 生物学，口腔癌与干细胞，(2) 颅面生物学，生物工程与再生医学，(3) 微生物 – 毒力机制和 CryoEM 高级成像，以及 (4) 转化遗传学， 表观遗传学和基因组学。我们的跨学科培训计划将学员与学院的导师联系起来 牙科、医学院、工程学院、琼森综合癌症中心、分子 生物研究所、干细胞研究所和加州纳米系统研究所。这些的整合 跨部门的中心和机构提供了丰富的培训环境和巨大的物质资源 和集中的核心设施。我们提供五个培训课程，(i) 牙医科学家实习生计划（双学位 DDS/PhD)，(ii) 牙医博士项目（牙医博士前研究培训），(iii) 牙医科学家 博士后研究员（牙医博士后培训），（iv）博士前博士实习生（口腔博士前培训） (v) 口腔健康博士后研究员（口腔健康博士后培训）。总的来说，我们提出的 培训计划将培训下一代牙医科学家和口腔健康科学家进行基础、 改善牙齿、口腔和颅面健康的转化和临床研究。 项目总结/摘要第 6 页 联系 PD/PI：Ton-That, Hung 项目叙述 加州大学洛杉矶分校牙科学院的机构培训拨款旨在培训下一代牙医 - 科学家和口腔健康科学家通过严格和可靠的方法进行基础、转化和临床研究 跨学科培训计划，以支持充满活力和多样化的牙科、口腔和颅面研究 劳动力。