Training in Neurotechnology Translation

我们寻求NIH的赞助，以支持在UCLA建立一个创新和成功的神经技术培训中心-UCLA神经技术翻译培训（TNT）-整合基础，翻译和临床神经科学和工程的多学科专业知识。预计神经系统疾病的负担将越来越重;预计神经技术，如假肢，成像和其他设备，将成为满足这一未满足需求的组成部分。TNT的总体使命是培养新一代的神经科学家和工程师，他们将成为转化神经技术领域的领导者，他们在临床神经科学中将技术从实验室转化到床边的纵向过程中具有专业知识。该培训计划建立在这样一种信念的基础上，即未来成功的翻译神经科学家不仅需要掌握科学知识，还需要在与翻译相关的基本问题上具有特定的知识和经验，包括实验和试验设计，统计，监管流程和障碍，以及神经技术翻译的业务方面。TNT的具体目标包括：（1）了解转化神经技术研究的范围（2）成为临床转化纵向过程的专家（3）学习如何定义转化研究的临床需求和实用性（4）科学严谨性的培训（5）监管途径和科学业务的培训包括沟通和（6）暴露和理解的行业观点和监管和商业障碍的转化神经技术。该计划将整合跨学科的曝光，培训中的关键活动包括：（1）神经技术领域的指导研究（2）临床沉浸体验（3）科学家和临床医生的双重指导（4）TNT研讨会系列（5）科学严谨性和负责任的研究行为的核心课程（6）参与校园创新和/或翻译活动和（7）提交个人资助申请。培训计划的核心是来自加州大学洛杉矶分校三所学校13个部门的多学科教师，他们在资金，出版和培训成功方面有着良好的记录。多个行业合作伙伴承诺参与培训并为学员提供教育机会，从而补充了培训经验。TNT将培养3名博士前和3名博士后学员（2年任期）。TNT是补充，并参与，在神经科学，工程，创新和翻译已经在加州大学洛杉矶分校建立的现有计划。

We seek sponsorship from the NIH to support the establishment of an innovative and successful training hub in neurotechnology at UCLA – the UCLA Training in Neurotechnology Translation (TNT) - integrating multidisciplinary expertise in basic, translational, and clinical neurosciences and engineering. The increasing burden of neurologic disease is projected to be significant; it is anticipated that neurotechnology, like prosthetics, imaging, and other devices, will be integral to meeting this unmet need. The overall mission of TNT is to train a new generation of neuroscientists and engineers who will be leaders in the field of translational neurotechnology who have expertise in the longitudinal process of translating technology from bench-to-bedside in clinical neurosciences. The training program builds on the belief that successful translational neuroscientists of the future will require not only mastery of science, but will require specific knowledge and experience in fundamental issues related to translation, including experimental and trial design, statistics, regulatory processes and hurdles, and the business aspects of neurotechnology translation. The specific objectives for TNT include: (1) Understanding the spectrum of translational neurotechnology research (2) Becoming experts in the longitudinal process of clinical translation (3) Learning how to define clinical needs and practicalities for translational research (4) Training in scientific rigor (5) Training in regulatory pathways and business of science, including communication and (6) Exposure and understanding of industry perspectives and regulatory and business hurdles in translational neurotechnology. The program will integrate exposure across disciplines, with key activities in training including: (1) Mentored research in the field of neurotechnology (2) Clinical immersion experience (3) Dual mentorship by a scientist and clinician (4) TNT Seminar Series (5) Core coursework in scientific rigor and the responsible conduct of research (6) Participation in campus-based innovation and/or translational activity and (7) Submission of an individual funding application. At the core of the training program is a multidisciplinary faculty from 13 departments across three schools at UCLA with a strong record of funding, publication, and training success. The training experience is complemented by commitment by multiple industry partners to participate in and provide educational opportunities for trainees. TNT will train 3 predoctoral and 3 postdoctoral trainees (2-year appointment). TNT is both complementary to, and participatory in, existing programs in neurosciences, engineering, innovation, and translation already well established at UCLA.