Training in Neurotechnology Translation

我们寻求美国国立卫生研究院的赞助，以支持在加州大学洛杉矶分校建立一个创新和成功的神经技术培训中心-加州大学洛杉矶分校神经技术翻译(TNT)培训-整合基础、翻译和临床神经科学和工程方面的多学科专业知识。神经疾病的负担预计会越来越大；预计神经技术，如假肢、成像和其他设备，将是满足这一未得到满足的需求的不可或缺的部分。TNT的总体使命是培养新一代神经科学家和工程师，他们将成为翻译神经技术领域的领导者，他们拥有将临床神经科学中的技术从工作台转化到床边的纵向过程的专业知识。该培训计划基于这样一种信念，即未来成功的翻译神经科学家不仅需要掌握科学知识，还需要在与翻译相关的基本问题上拥有专门的知识和经验，包括实验和试验设计、统计学、监管流程和障碍，以及神经技术翻译的业务方面。TNT的具体目标包括：(1)了解翻译神经技术研究的范围(2)成为临床翻译纵向过程的专家(3)学习如何确定翻译研究的临床需求和实用性(4)科学严谨性培训(5)监管途径和科学业务培训，包括交流和(6)接触和了解翻译神经技术的行业视角和监管和商业障碍。该计划将跨学科的曝光度与培训中的主要活动结合在一起，包括：(1)神经技术领域的指导性研究(2)临床沉浸体验(3)科学家和临床医生的双重指导(4)TNT系列研讨会(5)科学严谨性和负责任的研究的核心课程(6)参与基于校园的创新和/或翻译活动和(7)个人资金申请。该培训计划的核心是来自加州大学洛杉矶分校三所学校13个系的多学科教员，他们在资金、出版和培训方面取得了良好的记录。多个行业合作伙伴承诺参与培训并为学员提供教育机会，以补充培训经验。TNT将培训3名博士后和3名博士后实习生(为期2年)。TNT既是对加州大学洛杉矶分校已经很好地建立的神经科学、工程、创新和翻译方面的现有项目的补充，也是对这些项目的参与。

We seek sponsorship from the NIH to support the establishment of an innovative and successful training hub in neurotechnology at UCLA – the UCLA Training in Neurotechnology Translation (TNT) - integrating multidisciplinary expertise in basic, translational, and clinical neurosciences and engineering. The increasing burden of neurologic disease is projected to be significant; it is anticipated that neurotechnology, like prosthetics, imaging, and other devices, will be integral to meeting this unmet need. The overall mission of TNT is to train a new generation of neuroscientists and engineers who will be leaders in the field of translational neurotechnology who have expertise in the longitudinal process of translating technology from bench-to-bedside in clinical neurosciences. The training program builds on the belief that successful translational neuroscientists of the future will require not only mastery of science, but will require specific knowledge and experience in fundamental issues related to translation, including experimental and trial design, statistics, regulatory processes and hurdles, and the business aspects of neurotechnology translation. The specific objectives for TNT include: (1) Understanding the spectrum of translational neurotechnology research (2) Becoming experts in the longitudinal process of clinical translation (3) Learning how to define clinical needs and practicalities for translational research (4) Training in scientific rigor (5) Training in regulatory pathways and business of science, including communication and (6) Exposure and understanding of industry perspectives and regulatory and business hurdles in translational neurotechnology. The program will integrate exposure across disciplines, with key activities in training including: (1) Mentored research in the field of neurotechnology (2) Clinical immersion experience (3) Dual mentorship by a scientist and clinician (4) TNT Seminar Series (5) Core coursework in scientific rigor and the responsible conduct of research (6) Participation in campus-based innovation and/or translational activity and (7) Submission of an individual funding application. At the core of the training program is a multidisciplinary faculty from 13 departments across three schools at UCLA with a strong record of funding, publication, and training success. The training experience is complemented by commitment by multiple industry partners to participate in and provide educational opportunities for trainees. TNT will train 3 predoctoral and 3 postdoctoral trainees (2-year appointment). TNT is both complementary to, and participatory in, existing programs in neurosciences, engineering, innovation, and translation already well established at UCLA.