sTMS for Substance Use-disordered Veterans

本提案的目标是评估初步参与者对试点的反应，控制， 可行性研究，以评估6周后渴求、物质使用和生活质量的变化 一种低风险的非侵入性脑刺激技术， 磁刺激（sTMS），与假相比，在退伍军人与物质使用障碍 （SUD）。本申请的一个重要重点是评价可接受性、耐受性和 sTMS在该人群中的安全性。据我们所知，sTMS从未用于SUD， 作为这些流行疾病的未来治疗选择具有相当大的希望。然而 必须首先对这种方法的可接受性、耐受性和安全性进行初步研究。 这个项目是我们实现长期目标的第一步，我们的长期目标是将联合收割机 通过个体化心理治疗或药物治疗刺激，以减少SUD问题， 提高退伍军人的生活质量。

The goal of this proposal is to evaluate preliminary participant response to a pilot, controlled, feasibility study to evaluate changes in craving, substance use, and quality of life after 6 weeks of a low-risk non-invasive brain stimulation technique, called Synchronized Transcranial Magnetic Stimulation (sTMS), compared to sham, in Veterans with a substance use disorder (SUD). An important focus of this application will be evaluating the acceptability, tolerability, and safety of sTMS in this population. To our knowledge, sTMS has never been used for SUDs, and holds considerable promise as a future treatment option for these prevalent disorders. However initial work in the acceptability, tolerability, and safety of this approach must be conducted first. This project is the first step towards our long-term goal, which is to combine non-invasive brain stimulation with individualized psychotherapy or pharmacotherapy to reduce SUD problems and improve quality of life for Veterans.