Molecular Medicine Training Program at Cleveland Clinic/Case Western Reserve University

凯斯西储大学分子医学培训项目 医学是专门为研究生培训引入医学知识而设计的 促进与人类疾病相关的翻译研究。它是为数不多的独立的 美国的分子医学博士项目。它利用四个因素来 创造一个特别适合这一目的的环境。首先，该计划位于 勒纳研究所，克利夫兰诊所和 医学院历来密切合作，专注于尖端研究 关于人类疾病的原因和治疗。第二，新的核心课程已经出台 旨在为以下背景下提出的基本科学原则提供坚实的基础 人体器官系统和疾病。教师研究报告、实验室轮换、学生 研究研讨会和年度计划展示，加强翻译应用程序和 基本科学原理在整个培训过程中可能产生的临床影响。第三，培训 该计划包含了领导优秀翻译研究的广泛培训人员 我们的受训人员进行轮换和论文工作的实验室。它的范围和力量 这些实验室，它们的协作互动，以及培训人员支持 培训计划的实施是培训中大学科学环境的证据 程序。最后，为了确保每个受训者都了解临床方面 在他们的研究领域中，每个人都会选择一名临床合作导师，帮助组织个人 临床经验。通过这种经历，学员被介绍给患者诊断和 在第一手基础上进行治疗。临床联合导师仍在学生的论文中 委员会一直到毕业。此外，该方案在以下方面一直走在前列 项目评估，负责进行研究培训，严谨和可重复性培训， 性骚扰意识、个人发展计划和职业/职业 发展研讨会，提供有关不同职业道路的信息。这项建议 在培训计划中为6名受训人员寻求资金。此培训计划已获得 该项目获得了国家认可，并取得了很好的成果。自从我们的第一个班在2007年被录取 共有55名博士毕业生，平均毕业时间为5.38年。我们的 准备在生物医学工作队伍中担任不同角色的实习生，包括 美国国立卫生研究院资助的下一代实验室的领导人翻译基础科学 满足患者需求的原则。

The Molecular Medicine Training Program of the Case Western Reserve University School of Medicine is specifically designed to introduce medical knowledge into graduate training and foster translational research relevant to human disease. It is one of the very few stand-alone Molecular Medicine PhD programs in the United States. It takes advantage of four factors to create an environment particularly suited to this purpose. First, this Program is located in the Lerner Research Institute where physicians and scientists from both the Cleveland Clinic and the School of Medicine have historically worked closely together to focus cutting edge research upon the causes and treatments of human illness. Second, a novel core curriculum has been designed to provide a solid foundation in basic scientific principles presented in the context of human organ systems and disease. Faculty research presentations, lab rotations, student research seminars, and an annual program showcase reinforce the translational application and potential clinical impact of the basic scientific principles throughout training. Third, the Training Program contains a broad range of trainers heading outstanding translational research laboratories in which our trainees perform rotations and thesis work. The range and strength of these laboratories, their collaborative interactions, and the commitment of the trainers to support of the Training Program is evidence of the collegial scientific environment within the Training Program. Finally, to ensure that each of the trainees comes to understand the clinical aspects of their area of investigation, each selects a Clinical Co-Mentor who helps organize an individual clinical experience. Through this experience trainees are introduced to patient diagnosis and treatment on a first hand basis. The Clinical Co-Mentor remains on the student’s thesis committee through graduation. In addition, the Program has been at the forefront in including program evaluation, responsible conduct of research training, rigor and reproducibility training, sexual harassment awareness, individual development plans, and career/professional development seminars that provide information about diverse career pathways. This proposal seeks funding for 6 trainees within the Training Program. This Training Program has gained national recognition and has had excellent outcomes. Since our first class matriculated in 2007 there has been a total of 55 PhD graduates with an average time to degree of 5.38 years. Our trainees preparing to take their places in diverse roles in the biomedical workforce, including as the leaders of the next generations of NIH funded laboratories translating basic scientific principles to address patient needs.