Molecular Medicine Training Program at Cleveland Clinic/Case Western Reserve University

克利夫兰诊所/凯斯西储大学分子医学培训项目

• 批准号: 10268038
• 负责人: Jonathan D Smith
• 金额: $ 29.26万
• 依托单位: CLEVELAND CLINIC LERNER COM-CWRU
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10268038
• 关键词: Clinic; Molecular Medicine; Training Programs; Universities

The Molecular Medicine Training Program of the Case Western Reserve University School of Medicine is specifically designed to introduce medical knowledge into graduate training and foster translational research relevant to human disease. It is one of the very few stand-alone Molecular Medicine PhD programs in the United States. It takes advantage of four factors to create an environment particularly suited to this purpose. First, this Program is located in the Lerner Research Institute where physicians and scientists from both the Cleveland Clinic and the School of Medicine have historically worked closely together to focus cutting edge research upon the causes and treatments of human illness. Second, a novel core curriculum has been designed to provide a solid foundation in basic scientific principles presented in the context of human organ systems and disease. Faculty research presentations, lab rotations, student research seminars, and an annual program showcase reinforce the translational application and potential clinical impact of the basic scientific principles throughout training. Third, the Training Program contains a broad range of trainers heading outstanding translational research laboratories in which our trainees perform rotations and thesis work. The range and strength of these laboratories, their collaborative interactions, and the commitment of the trainers to support of the Training Program is evidence of the collegial scientific environment within the Training Program. Finally, to ensure that each of the trainees comes to understand the clinical aspects of their area of investigation, each selects a Clinical Co-Mentor who helps organize an individual clinical experience. Through this experience trainees are introduced to patient diagnosis and treatment on a first hand basis. The Clinical Co-Mentor remains on the student’s thesis committee through graduation. In addition, the Program has been at the forefront in including program evaluation, responsible conduct of research training, rigor and reproducibility training, sexual harassment awareness, individual development plans, and career/professional development seminars that provide information about diverse career pathways. This proposal seeks funding for 6 trainees within the Training Program. This Training Program has gained national recognition and has had excellent outcomes. Since our first class matriculated in 2007 there has been a total of 55 PhD graduates with an average time to degree of 5.38 years. Our trainees preparing to take their places in diverse roles in the biomedical workforce, including as the leaders of the next generations of NIH funded laboratories translating basic scientific principles to address patient needs.

凯斯西储大学分子医学培训项目 医学是专门设计的，以介绍医学知识到研究生培训， 促进与人类疾病相关的转化研究。它是为数不多的独立的 美国的分子医学博士课程。它利用四个因素， 创造一个特别适合这一目的的环境。首先，该计划位于 勒纳研究所，医生和科学家从克利夫兰诊所和 医学院历来密切合作，专注于尖端研究 人类疾病的病因和治疗方法第二，新的核心课程已经 旨在提供一个坚实的基础，在基本的科学原理提出的背景下， 人体器官系统和疾病。教师研究报告，实验室轮换，学生 研究研讨会和年度计划展示加强了翻译应用， 在整个培训过程中，基本科学原理的潜在临床影响。第三，培训 该计划包含广泛的培训师领导优秀的翻译研究 我们的实习生在实验室进行轮换和论文工作。的范围和强度 这些实验室，他们的合作互动，以及培训师的承诺，以支持 培训计划的目的是证明培训中的大学科学环境 程序.最后，为了确保每个受训者都了解临床方面的知识， 在他们的研究领域，每个人都选择一个临床共同导师，帮助组织一个人 临床经验。通过这种经验，学员被介绍给病人的诊断， 第一手的治疗。临床共同导师仍然在学生的论文 委员会通过毕业。此外，该方案还在以下方面走在前列： 项目评估，负责任的研究培训，严谨性和可重复性培训， 性骚扰意识、个人发展计划和职业/专业 发展研讨会，提供有关不同职业道路的信息。这项建议 在培训方案内为6名受训人员寻求资金。该培训项目已获得 获得了国家的认可，并取得了良好的成果。自从2007年我们第一个班被录取以来 共有55名博士毕业生，平均学位时间为5.38年。我们 准备在生物医学劳动力中担任不同角色的学员，包括 下一代NIH资助实验室的领导者将基础科学 满足患者需求的原则。