An Instrument to Assess the Functional Impact of Chronic Pain
An Instrument to Assess the Functional Impact of Chronic Pain
批准号:
10436545
负责人:
Brian R Clark
金额:
$72.54万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2019
资助国家:
美国
项目状态:
已结题
起止时间:
2019-09-30 至 2023-08-31
关键词:
Activities of Daily LivingAssessment toolBiometryClinical ResearchClinical TrialsCommunicationComplementComplexComputer softwareComputerized Medical RecordCustomDataDementiaDevicesEffectivenessEvaluationFreedomGrantHealth Care CostsHeart DiseasesHeart RateIndividualInterventionLanguageLettersLifeLiteratureMalignant NeoplasmsMeasurementMeasuresMethodologyMethodsModelingMotionNatureOpioidPainPain MeasurementPain intensityPain managementPathologyPatient Outcomes AssessmentsPatient Self-ReportPatientsPharmaceutical PreparationsPhasePhysical FunctionPhysiologicalPrimary Health CareProcessPropertyPsychometricsQuality of lifeReportingResearchRotationSkinSmall Business Innovation Research GrantStatistical ModelsSurfaceSystemTechnologyTemperatureTranslationsTreatment EfficacyWorkWorkers&apos CompensationWristanalytical methodbasechronic painchronic pain managementchronic pain patientclinical paincohortcostdesigndisabilityeffective therapyexperiencefunctional disabilityheart rate variabilityimprovedimproved outcomeinnovationinstrumentkinematicslight weightnovelphase 2 testingprofiles in patientsprototyperesponsesensor technologytheoriestooltraitusability
中文摘要
项目总结/文摘
英文摘要
Project Summary/Abstract
Evaluation and treatment for chronic pain are major contributors to rising healthcare costs. Although accurate
assessment of pain and function is the cornerstone to successful chronic pain management, systematic, objective
assessment of the functional impact of pain remains exceptionally challenging in practice. The intricate nature of
chronic pain demands a comprehensive, multi-mode assessment methodology that combines subjective Patient
Reported Outcomes (PROs) with objective data. There is significant potential to reduce the costs associated
with chronic pain and simultaneously improve outcomes by leveraging novel, cutting-edge sensing technology
and analytical methods to provide new pain assessment and treatment evaluation information.
The proposed Fast Track SBIR effort will develop and validate the reliable, low-cost KnowPain instrument.
KnowPain will objectively and quantitatively assess the functional impact of chronic pain (FIP) using measures
derived from six degrees-of-freedom (6-DOF) motion, heart rate, skin surface temperature, and skin conductivity
collected via a specially designed, ergonomic wrist-worn biometric sensing instrument. The new assessment
instrument will apply advanced psychometric methods to both physiologic and kinematic data to provide precise
scores for functional impairment due to chronic pain. The validated instrument will be a fully-automated,
stand-alone product available to clinicians assessing and treating chronic pain in a variety of settings.
The KnowPain instrument will be worn by the patient for a period of up to one week, after which collected
data will automatically be uploaded and processed by the system's custom software using Multidimensional Item
Response Theory models. The assessment results will be presented to the clinician in an easy-to-understand
report and will include longitudinal results, confidence estimates, and normative data to enable comparisons
both within and between patients. The system will include provision to interface with electronic medical records
(EMRs).
Accurate functional assessment is a crucial component in the effective treatment of chronic pain. The
proposed approach will supplement existing methods for assessing patient function (e.g., PROs) by providing
novel and highly complementary information for a more complete (and often unobserved) picture of the impact of
chronic pain on patient function. KnowPain measures will provide important data on the practical consequences
of pain and on treatment efficacy. The impact of chronic pain on daily life is a primary concern for patients;
patients assign great value to pain interventions that improve their ability to participate in normal daily activities.
The proposed KnowPain system will provide currently unavailable objective data to facilitate informed and
effective pain management decisions, leading to: (1) reduced functional impairment, increased mobility, and
improved quality-of-life; (2) de-emphasis on medications, particularly opioids; and (3) reduced disability and
associated healthcare costs, including worker's compensation.
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会议论文
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海外基金