West African Emerging Infectious Disease Research Center (WA-EIDRC)
West African Emerging Infectious Disease Research Center (WA-EIDRC)
批准号:
10440593
负责人:
Kristian Graugaard Andersen
金额:
$26.63万
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
已结题
起止时间:
2021-08-17 至 2023-04-30
关键词:
AcuteAffectAfricaAfricanAnimalsAreaAwarenessBiological AssayChiropteraClinicalClinical ManagementClustered Regularly Interspaced Short Palindromic RepeatsCollaborationsCommunicable DiseasesCommunicationCommunitiesCountryDecentralizationDetectionDevelopmentDiagnosticDiagnostic testsDisease OutbreaksEbolaEducational workshopEmerging Communicable DiseasesEnsureEpidemicEpidemiologistEvolutionFoundationsFrequenciesFundingFutureGenomicsGoalsHealthHumanImmune responseInfectionInfectious Diseases ResearchInfrastructureKnowledgeLassa virusLiberiaMetagenomicsMethodsMolecular EpidemiologyNational Institute of Allergy and Infectious DiseaseNatural HistoryNigeriaOutcomePathogenesisPatientsPlant RootsPrevalencePrevention strategyProtocols documentationPublic HealthRNARNA VirusesRapid diagnosticsReagentResearchResearch PersonnelRiskRisk FactorsRodentSecuritySenegalSierra LeoneStandardizationSurveysSystemTechnology TransferTestingTrainingUnited StatesUnited States National Institutes of HealthViral Hemorrhagic FeversVirusVirus DiseasesWorkWorld BankZIKAbasecohortcomputerized toolsdata sharingdiagnostic assaydiagnostic technologiesemerging pathogenexperienceflexibilitygenome sequencingimprovedmetagenomic sequencingmicrobialnew technologynovelpandemic diseasepandemic preparednesspathogenpathogenic viruspreventpriority pathogenpublic health emergencypublic health interventionresponsesurveillance studytechnology developmenttooltransmission processviral transmission
中文摘要
确保世界不受微生物威胁是一项紧迫的挑战,因为疫情对人类造成了严重影响
英文摘要
Ensuring a world safe from microbial threats is a pressing challenge, as outbreaks exact tolls on human
health, disrupt regional security, and have the potential to rapidly escalate into global crises. In recent
years, severe outbreaks of Ebola, Lassa, Zika, and other emerging viruses have illustrated how vulnerable
the world is to threats from RNA viral pathogens. These public health emergencies have exposed the
urgent need for improved infrastructure, scientific knowledge, and diagnostic tools in areas of the world
most at risk, and underscore the need for proactive pathogen surveillance, detection, and discovery.
West Africa has a disproportionate vulnerability to outbreaks, but we lack awareness of acute threats,
their natural history, and effective strategies for prevention. Rooted research between local and global
partners, combined with novel assays and strategies for pandemic preparedness is required to answer
these questions. We will build the capacity to rapidly respond to future outbreaks by establishing the
West African Emerging Infectious Disease Research Center. This center will expand on years of successful
cross-disciplinary research and capacity building, bringing together leading researchers from the United
States, Liberia, Nigeria, Senegal, and Sierra Leone. We will: (1) perform comprehensive surveys of acute
RNA viral disease and determine critical threats circulating in hosts and reservoirs; (2) identify risk factors
of virus transmission and evolution; (3) dissect pathogenesis and natural history of severe RNA viral
diseases; and (4) determine diagnostic criteria for infection outcome to guide public health interventions.
Our work will significantly expand research capacity in West Africa via technology development of novel
solutions for surveillance, diagnostics, and pathogen discovery. By establishing our center with a focus on
priority pathogen research, technology transfer, training, and capacity building, we will develop flexible
strategies for detecting, mitigating, and preventing the emergence of future infectious disease outbreaks.
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会议论文
West African Emerging Infectious Disease Research Center (WA-EIDRC)
-
批准号:10653441
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项目类别:
-
资助金额:$184.89万
-
财政年份:2022
-
负责人:Kristian Graugaard Andersen
-
依托单位:
Consortium for Viral Systems Biology (CViSB)
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批准号:10469781
-
项目类别:
-
资助金额:$59.71万
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财政年份:2021
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负责人:Kristian Graugaard Andersen
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依托单位:
Consortium for Viral Systems Biology Administrative Core
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批准号:10469782
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项目类别:
-
资助金额:$59.71万
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财政年份:2021
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负责人:Kristian Graugaard Andersen
-
依托单位:
West African Emerging Infectious Disease Research Center (WA-EIDRC)
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批准号:10631738
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项目类别:
-
资助金额:$35.86万
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财政年份:2020
-
负责人:Kristian Graugaard Andersen
-
依托单位:
West African Emerging Infectious Disease Research Center (WA-EIDRC)
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批准号:10910587
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项目类别:
-
资助金额:$23.6万
-
财政年份:2020
-
负责人:Kristian Graugaard Andersen
-
依托单位:
West African Emerging Infectious Disease Research Center (WA-EIDRC)
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批准号:10394323
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项目类别:
-
资助金额:$174.99万
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财政年份:2020
-
负责人:Kristian Graugaard Andersen
-
依托单位:
West African Emerging Infectious Disease Research Center (WA-EIDRC)
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批准号:10842168
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项目类别:
-
资助金额:$80.18万
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财政年份:2020
-
负责人:Kristian Graugaard Andersen
-
依托单位:
West African Emerging Infectious Disease Research Center (WA-EIDRC)
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批准号:10616665
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项目类别:
-
资助金额:$174.13万
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财政年份:2020
-
负责人:Kristian Graugaard Andersen
-
依托单位:
Consortium for Viral Systems Biology (CViSB)
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批准号:10248803
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项目类别:
-
资助金额:$25.0万
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财政年份:2018
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负责人:Kristian Graugaard Andersen
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依托单位:
Consortium for Viral Systems Biology Administrative Core
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批准号:10579082
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项目类别:
-
资助金额:$7.5万
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财政年份:2018
-
负责人:Kristian Graugaard Andersen
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依托单位:
Systems biology of Ebola virus and Lassa virus determinants of infection outcome
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批准号:10310606
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项目类别:
-
资助金额:$11.52万
-
财政年份:2018
-
负责人:Kristian Graugaard Andersen
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依托单位:
Consortium for Viral Systems Biology Administrative Core
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批准号:10310601
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项目类别:
-
资助金额:$7.29万
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财政年份:2018
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负责人:Kristian Graugaard Andersen
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依托单位:
Project 2
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批准号:10558424
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项目类别:
-
资助金额:$64.26万
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财政年份:2018
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负责人:Kristian Graugaard Andersen
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依托单位:
Consortium for Viral Systems Biology (CViSB)
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批准号:10579081
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项目类别:
-
资助金额:$45.0万
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财政年份:2018
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负责人:Kristian Graugaard Andersen
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依托单位:
Consortium for Viral Systems Biology (CViSB)
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批准号:10374714
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项目类别:
-
资助金额:$255.0万
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财政年份:2018
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负责人:Kristian Graugaard Andersen
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依托单位:
Administrative Core
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批准号:10558419
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项目类别:
-
资助金额:$31.68万
-
财政年份:2018
-
负责人:Kristian Graugaard Andersen
-
依托单位:
Consortium for Viral Systems Biology (CViSB)
-
批准号:10356250
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项目类别:
-
资助金额:$45.0万
-
财政年份:2018
-
负责人:Kristian Graugaard Andersen
-
依托单位:
Systems biology of Ebola virus and Lassa virus determinants of infection outcome
-
批准号:10374720
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项目类别:
-
资助金额:$42.5万
-
财政年份:2018
-
负责人:Kristian Graugaard Andersen
-
依托单位:
Systems biology of Ebola virus and Lassa virus determinants of infection outcome
-
批准号:10579087
-
项目类别:
-
资助金额:$7.5万
-
财政年份:2018
-
负责人:Kristian Graugaard Andersen
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依托单位:
Center for Viral Systems Biology (CViSB)
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批准号:10558418
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项目类别:
-
资助金额:$265.04万
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财政年份:2018
-
负责人:Kristian Graugaard Andersen
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依托单位:
海外基金