A Biomedical Mass Spectrometry Resource: Ongoing Driving Biomedical Projects

生物医学质谱资源:持续推动生物医学项目

基本信息

  • 批准号:
    10441142
  • 负责人:
  • 金额:
    $ 65.99万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2020
  • 资助国家:
    美国
  • 起止时间:
    2020-04-01 至 2024-03-31
  • 项目状态:
    已结题

项目摘要

Project Summary The Washington University NIGMS Biomedical Resource seeks to continue its successful collaborative work with biomedical researchers engaged in understanding disease and maintaining human health. This Resource supports a wide array of scientists requiring structural proteomics and complex lipidomics by expertly using mass spectrometry tools, many of which were developed at this Resource over the last 15 years. The dedicated scientists at the Resource have more than a century of combined experience and continue to collaborate with investigators working on important biomedical problems including viral pathogens like Ebola, Dengue, Zika, and Marburg, bacterial pathogens such as the causative agents of tuberculosis and leishmania, plasmodia that cause malaria, Alzheimer's and Parkinson's diseases, diabetes, metabolic syndrome, urinary tract infections, and cancer. Resource staff investigators, motivated by national and international collaborators in academic, industrial, and governmental laboratories, provide support for the study of cellular calcium regulation, lipid metabolism, antibody-antigen binding, and many other problems in structural and functional biology. In addition, the dedicated scientists at this Resource will support successful dissemination, training, and outreach to the scientific and broader communities. This grant will allow them to continue the application of mass spectrometry to these problems as they transition to other sources of support that allow them to honor commitments to their large and diverse group of collaborators.
项目总结

项目成果

期刊论文数量(3)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Development of a High-Throughput Mass Spectrometry-Based SARS-CoV-2 Immunoassay.
  • DOI:
    10.1021/acs.analchem.3c02421
  • 发表时间:
    2023-12
  • 期刊:
  • 影响因子:
    7.4
  • 作者:
    Jie Sun;Jong Hee Song;Mary K Danielson;Nathan D Colley;Alia Thomas;David Hambly;J. C. Barnes;Michael L. Gross
  • 通讯作者:
    Jie Sun;Jong Hee Song;Mary K Danielson;Nathan D Colley;Alia Thomas;David Hambly;J. C. Barnes;Michael L. Gross
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MICHAEL L GROSS其他文献

MICHAEL L GROSS的其他文献

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{{ truncateString('MICHAEL L GROSS', 18)}}的其他基金

New chemical probes enable Mass Spectrometry-based footprinting of human protein structure in lipid membranes and cells
新的化学探针能够基于质谱分析脂膜和细胞中的人类蛋白质结构
  • 批准号:
    10350642
  • 财政年份:
    2019
  • 资助金额:
    $ 65.99万
  • 项目类别:
NEW CHEMICAL PROBES ENABLE MASS SPECTROMETRY-BASED FOOTPRINTING OF HUMAN PROTEIN STRUCTURE IN LIPID
新的化学探针实现了基于质谱的脂质中人类蛋白质结构的足迹
  • 批准号:
    10390166
  • 财政年份:
    2019
  • 资助金额:
    $ 65.99万
  • 项目类别:
NEW CHEMICAL PROBES ENABLE MASS SPECTROMETRY-BASED FOOTPRINTING OF HUMAN PROTEIN STRUCTURE IN LIPID MEMBRANES AND CELLS
新的化学探针能够对脂质膜和细胞中的人体蛋白质结构进行基于质谱的足迹分析
  • 批准号:
    10587527
  • 财政年份:
    2019
  • 资助金额:
    $ 65.99万
  • 项目类别:
A MASS SPECTROMETER FOR PROTEIN FOOTPRINTING
用于蛋白质足迹分析的质谱仪
  • 批准号:
    8637341
  • 财政年份:
    2014
  • 资助金额:
    $ 65.99万
  • 项目类别:
APPROACHES TO IMPROVE PROTEIN FOOTPRINTING: HIGH PRESSURE DIGESTION
改善蛋白质足迹的方法:高压消化
  • 批准号:
    8361405
  • 财政年份:
    2011
  • 资助金额:
    $ 65.99万
  • 项目类别:
HIGH ENERGY COLLISIONAL ACTIVATION
高能碰撞激活
  • 批准号:
    8361422
  • 财政年份:
    2011
  • 资助金额:
    $ 65.99万
  • 项目类别:
UNDERGRADUATE TRAINING IN MASS SPECTROMETRY
质谱学本科培训
  • 批准号:
    8361432
  • 财政年份:
    2011
  • 资助金额:
    $ 65.99万
  • 项目类别:
VISITING SCIENTISTS
访问科学家
  • 批准号:
    8361338
  • 财政年份:
    2011
  • 资助金额:
    $ 65.99万
  • 项目类别:
STRUCTURAL STUDIES OF GRAMICIDIN & OTHER SELF-ASSOCIATING PEPTIDES
短杆菌肽的结构研究
  • 批准号:
    8361321
  • 财政年份:
    2011
  • 资助金额:
    $ 65.99万
  • 项目类别:
CONTRIBUTED PRESENTATIONS AT CONFERENCES
在会议上发表演讲
  • 批准号:
    8361333
  • 财政年份:
    2011
  • 资助金额:
    $ 65.99万
  • 项目类别:
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