Training Program in Basic and Translational Cardiovascular Science

摘要 这是第9个年头的培训计划的续签申请，该计划寻求资金支持博士前和 心血管疾病多学科研究项目的博士后研究实习生 从分子和细胞研究、成像、生物医学工程到翻译科学。在.期间 在上一个资助周期中，我们非常成功地将我们的培训计划从31名教职员工扩大到5名 几年前在这场竞争中续签了40名教职员工。我们培训项目的教职员工来自五个不同的 学校/学院。事实上，培训计划对我们的机构产生了高度协同的影响；我们 通过机构资助成功建立了新的心血管研究中心(CVRC) 来自加州大学戴维斯分校的五所不同的学校和大学，将于2017年秋季推出。课程和 培训方案内开展的活动已被用作#年其他培训赠款的范本。 在校园内进行翻译研究，因此，为加州大学戴维斯分校更广泛的受训人员提供服务。 该方案由内科和#年研究生研究生部主持。 分子、细胞和综合生理学(MCIP)、药理学和毒理学(PTX)、生物化学、 分子、细胞和发育生物学(BMCDB)、生物物理学(BPH)和生物医学工程 (BME)，一个真正的多学科项目。培训计划的目标是产生一种新的混合 准备好交流思想、专业知识和技术以实现直接和有效的流动的科学家 以及将基础科学发现转化为临床测试和应用，以及产生 可以在基础细胞水平上测试的机械性假说，直接来自临床研究。 这样一个综合计划的优势是巨大和深远的。通过将临床导师合并在一起 通过基础科学博士后和博士后培训，我们的目标是培养新的博士和博士后 博士后研究人员不仅有能力建立独立的研究，而且还擅长于 识别相关的基础科学问题，并将其整合为与临床相关的答案和解决方案。

ABSTRACT This is a renewal application of a training program in its 9th year that seeks funding to support predoctoral and postdoctoral research trainees in a multidisciplinary research program in cardiovascular and vascular diseases spanning from molecular and cellular studies, imaging, biomedical engineering, to translational science. During the last funding cycle, we have been highly successful in expanding our training program from 31 faculty five years ago to 40 faculty in this competing renewal. The faculty in our Training Program are from five different schools/Colleges. Indeed, the training program has had a highly synergistic impact on our institution; we have been successful in establishing a new Cardiovascular Research Center (CVRC) through institutional funding from five different schools and colleges at UC Davis which will be launched in Fall 2017. The curriculum and activities developed within the training program have been used as models for other training grants in translational research on campus and hence, serve a wider group of trainees at UC Davis. The Program operates under the auspices of the Department of Internal Medicine and the Graduate Studies in Molecular, Cellular and Integrative Physiology (MCIP), Pharmacology and Toxicology (PTX), Biochemistry, Molecular, Cellular and Developmental Biology (BMCDB), Biophysics (BPH) and Biomedical Engineering (BME), a truly multidisciplinary program. The goal of the Training Program is to produce a new blend of scientists who are poised to exchange ideas, expertise, and techniques leading to the direct and effective flow and translation of basic science discoveries into clinical testing and applications, as well as generate mechanistic hypotheses that can be tested at the basic cellular level, directly derived from clinical research. The advantages of such an integrated program are vast and far reaching. By merging clinical mentors together with pre-doctoral and post-doctoral trainees in basic science, our objectives are to foster new Ph.D.s and postdoctoral researchers who are not only capable of establishing independent research, but are also adept to recognizing and integrating relevant basic science questions into clinically germane answers and solutions.