Testing cross-generational effects of the Raising Healthy Children intervention

测试“养育健康儿童”干预措施的跨代效应

• 批准号: 10448447
• 负责人: JENNIFER A BAILEY
• 金额: $ 31.04万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-15 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10448447
• 关键词: 21 year old; Academic skills; Achievement; Adult; Adult Children; Age; Area; Biological; Caregivers; Characteristics; Child; Child Rearing; Childhood; Cohort Effect; Control Groups; Costs and Benefits; Data; Data Collection; Developmental Delay Disorders; Economics; Enrollment; Exhibits; Family; Generations; Health; Heavy Drinking; Intervention; Light; Link; Long-Term Effects; Longterm Follow-up; Mate Selections; Mediation; Mediator of activation protein; Mental Health; Modeling; Parents; Participant; Pediatrics; Performance; Personal Satisfaction; Problem behavior; Public Health; Publishing; Reporting; Research Personnel; Schools; Social Development; Testing; Time; Violence; Youth; antisocial behavior; anxiety symptoms; base; depressive symptoms; early pregnancy; elementary school; experience; follow-up; group intervention; high school; improved; intergenerational; intervention effect; intervention participants; longitudinal design; next generation; novel; offspring; parent project; positive youth development; preventive intervention; prospective; reduced substance use; substance use; teacher; universal prevention; young adult

In recent decades, researchers have developed an array of tested-effective and promising universal, school- and family-based preventive interventions, such as Raising Healthy Children (RHC), that reduce substance use and other problem behaviors and promote positive youth development. The Seattle Social Development Project (SSDP) is a quasi-experimental test of RHC, a school-based, universal preventive intervention delivered in elementary school (Grades 1 – 6). SSDP has followed participants (n = 808) from elementary school through age 39 (1985 – 2014; 15 data collections; 88% retention). Follow-up data show that the RHC intervention demonstrated long-term benefits for participants' health and well-being into adulthood, including lowered rates of mental health problems, heavy alcohol use, antisocial behavior, and early pregnancy, as well as higher educational attainment. Many youth who experienced the RHC preventive intervention as part of the SSDP later became parents. Known associations exist between parental mental health, substance use, antisocial behavior, and academic attainment and their children's functioning. The fact that RHC showed long-term benefits in these areas raises the exciting possibility that benefits experienced by intervention participants may echo into the next generation. This three year R01 project will analyze existing prospective data linking 2 generations from SSDP and SSDP-The Intergenerational Project (SSDP-TIP), which followed up SSDP participants and their children. SSDP-TIP began in 2002 when SSDP participants were about 27 years old, and included those SSDP participants who had become parents, the oldest biological child with whom they had regular contact, and a second caregiver who shared responsibility for raising the child, when present. New families were enrolled in the study as SSDP participants became parents for the first time. SSDP-TIP data were collected repeatedly between 2002 and 2018 (10 data collections, n = 426 families). Offspring ranged between ages 4 and 29 years (M = 17.2, SD = 6.1) in 2018. Of the SSDP parents participating in TIP, 79 received the RHC intervention in grades 1-6 (full intervention), 141 received the intervention in grades 5-6 only (late intervention), and 121 were in the control group. Prior analyses published in JAMA: Pediatrics demonstrated cross-generational intervention effects. The offspring of RHC intervention participants in the full intervention group were less likely to exhibit a range of developmental delays at ages 1- 5, had lower levels of teacher-rated behavior problems and higher levels of teacher-rated academic skills and performance (ages 6-18), and were less likely to report substance use by age 18. The proposed project will expand on these groundbreaking findings by (Aim 1) testing long-term effects of the RHC intervention on parenting practices and mate selection, (Aim 2) testing cross-generational effects of the intervention among young adult offspring (ages 18-25), and (Aim 3) testing hypothesized mechanisms of long-term and cross- generational intervention effects.

近几十年来，研究人员开发了一系列经过测试有效且有前景的通用、 基于学校和家庭的预防性干预措施，例如养育健康儿童 (RHC)，可减少 物质使用和其他问题行为，促进青少年积极发展。西雅图社交 发展项目（SSDP）是 RHC 的准实验测试，RHC 是一种以学校为基础的通用预防性 在小学（1-6 年级）进行干预。 SSDP 跟踪参与者 (n = 808) 小学至 39 岁（1985 年至 2014 年；15 次数据收集；88% 保留率）。后续数据显示 RHC 干预措施证明对参与者成年后的健康和福祉具有长期益处， 包括降低心理健康问题、酗酒、反社会行为和早期 怀孕以及较高的教育程度。许多经历过 RHC 预防的青少年 作为 SSDP 的一部分，后来成为父母进行干预。父母心理之间存在已知的关联 健康、药物滥用、反社会行为、学业成就及其孩子的功能。事实 RHC 在这些领域显示出长期效益，这提出了令人兴奋的可能性： 干预参与者可能会影响下一代。这个为期三年的 R01 项目将分析现有的 连接 SSDP 和 SSDP-代际项目 (SSDP-TIP) 两代人的前瞻性数据，其中 对 SSDP 参与者及其孩子进行了随访。 SSDP-TIP 始于 2002 年，当时 SSDP 参与者 大约27岁，包括那些已经成为父母的SSDP参与者，最大的亲生孩子 与他们有定期联系的人，以及共同承担抚养孩子责任的第二个照顾者， 当存在时。当 SSDP 参与者第一次成为父母时，新的家庭就被纳入了这项研究。 SSDP-TIP 数据在 2002 年至 2018 年间重复收集（10 个数据收集，n = 426 个家庭）。 2018 年，后代年龄介于 4 岁至 29 岁之间（M = 17.2，SD = 6.1）。 SSDP 父母中 参与 TIP 的 79 名学生在 1-6 年级接受了 RHC 干预（全面干预），141 名学生接受了 仅对5-6年级进行干预（后期干预），对照组有121人。先前发表的分析 《美国医学会杂志》：儿科证明了跨代干预效果。 RHC 干预的后代 全面干预组的参与者在 1 岁至 1 岁期间表现出一系列发育迟缓的可能性较小 5、教师评价的行为问题水平较低，而教师评价的学术技能和水平较高 表现（6-18 岁），并且在 18 岁时报告物质使用的可能性较小。拟议的项目将 通过（目标 1）测试 RHC 干预的长期影响来扩展这些突破性的发现 养育方式和择偶，（目标 2）测试干预措施的跨代影响 年轻成年后代（18-25 岁），以及（目标 3）测试长期和交叉的假设机制 代际干预效应。