Hopkins' Economics of Alzheimer's Disease and Services (HEADS) Center

摘要-总体 本申请要求资助建立霍普金斯的阿尔茨海默病经济学和服务 （HEADS）中心。该中心的总体目标是推进以人口为基础的科学，解决ADRD 护理及其经济后果。我们将通过以下两个主题的研究来实现这一目标：（1） 识别和量化ADRD护理需求的范围和相关的经济后果，以及（2） 审查服务的组织、筹资和提供如何影响可获得性、可负担性、质量， 和ADRD护理的公平性。在每个主题中，HEADS中心的研究将强调家庭和无报酬 差距和差距。我们通过两个具体目标来实现我们的总体目标和解决中心的主题。 具体目标1是在HEADS中心的领域产生关于ADRD护理的新知识， 专题聚焦。具体目标2是推进ADRD经济学和卫生服务研究领域 通过培养新兴和成熟的调查人员，发展尖端的研究， 在这方面，我们的工作重点是加强基础设施、传播新知识以及与政策和实践界建立联系。的 HEADS中心将通过四个核心的基础设施实现其目标。核心A，行政 和研究支持核心将通过协调和执行中心的战略愿景， 管理研究，方法，数据，社区建设和跨核心的传播资源。核心B， 该计划发展核心将提供资金、跨学科研究指导和监管 监测新的试点研究，可以在我们的主题内推进研究，发展职业生涯， 研究人员解决这些主题，并吸引调查人员到外地。核心D，外部研究 资源支持和传播核心，将建立从事研究的科学家社区 与HEADS主题相关，促进严格使用研究资源，传播科学证据 在我们的主题内开发，并与主要利益相关者和倡导组织建立伙伴关系， 将调查结果转化为政策和实践。核心E，远程数据飞地核心将创建和维持一个 高容量、安全的计算环境，可以产生新的调查和调查人员 在我们的主题范围内开展项目，利用ADRD相关数据之间的独特联系，其中许多 严格的安全要求。HEADS中心将利用约翰霍普金斯大学的独特优势 （霍普金斯）建立一个跨学校，跨学科和多样化的环境，发展和执行 创新研究，以推进基于人口的科学，解决ADRD护理及其经济 后果

Abstract – Overall This application requests funding to establish the Hopkins’ Economics of Alzheimer’s Disease & Services (HEADS) Center. The Center’s overall goal is to advance population-based science that addresses ADRD care and its economic consequences. We will meet this goal through research that addresses two themes: (1) Identifying and quantifying the range of ADRD care needs and related economic consequences and (2) Examining how the organization, financing, and delivery of services affects accessibility, affordability, quality, and equity of ADRD care. Within each theme, HEADS Center research will emphasize family and unpaid caregiving and disparities. We meet our overall goal and address Center themes through two Specific Aims. SPECIFIC AIM 1 is to generate new knowledge concerning ADRD care in the areas of the HEADS Center's thematic focus. SPECIFIC AIM 2 is to advance the field of ADRD economics and health services research and its impact by nurturing emerging and established investigators, developing a cutting-edge research infrastructure, disseminating new knowledge, and forging linkages with policy and practice communities. The HEADS Center will accomplish its Aims through an infrastructure of four Cores. Core A, the Administrative and Research Support Core will develop and execute the Center’s strategic vision by coordinating and managing research, methods, data, community-building, and dissemination resources across Cores. Core B, the Program Development Core will provide funding, interdisciplinary research mentorship, and regulatory monitoring for novel pilot studies that can advance research within our themes, develop the careers of researchers addressing these themes, and attract investigators to the field. Core D, the External Research Resources Support and Dissemination Core, will build the community of scientists engaged in research related to HEADS themes, facilitate rigorous use of research resources, disseminate scientific evidence developed within our themes, and nurture partnerships with key stakeholders and advocacy organizations to translate findings into policy and practice. Core E, the Remote Data Enclave Core will create and sustain a high-capacity, secure computing environment, that can generate new investigations and investigators pursuing projects within our themes that leverage unique linkages between ADRD related data, many with strict security requirements. The HEADS Center will leverage unique strengths at Johns Hopkins University (Hopkins) to build a cross-school, interdisciplinary, and diverse environment for developing and executing innovative research to advance population-based science that addresses ADRD care and its economic consequences.