Building Implementation Science Capacity at Makerere University to Strengthen the Response to the HIV/AIDS Epidemic in Uganda

建设麦克雷雷大学的实施科学能力，以加强对乌干达艾滋病毒/艾滋病流行的应对

• 批准号: 8896105
• 负责人: MOSES Robert KAMYA
• 金额: $ 30.42万
• 依托单位: MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-05-11 至 2020-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8896105
• 关键词: AIDS prevention; AIDS/HIV problem; Africa; Anti-Retroviral Agents; California; Caring; Clinical Research; Collaborations; Decision Making; Epidemic; Faculty; Foundations; Funding; Goals; Grant; HIV; Health Sciences; Health Services Accessibility; Humanities; Individual; Institution; International Agencies; Investments; Leadership; Malaria; Master' s Degree; Medical; Mentors; Pharmaceutical Preparations; Policies; Policy Maker; Postdoctoral Fellow; Public Health; Research; Research Training; Resources; San Francisco; Scientist; Services; Site; Social Sciences; Training; Training Programs; Translating; Tuberculosis; Uganda; United States National Institutes of Health; Universities; Work; career; college; evidence base; implementation science; medical schools; programs; response

 DESCRIPTION (provided by applicant): Although significant resources have been invested in HIV programs, Uganda is still far from the universal access-to-care target of 80%. While Uganda has developed highly successful research collaborations in HIV, tuberculosis, and malaria over the last 30 years, most of this work has been focused on clinical research, and the findings have not always translated into policy and practice changes. At present, we need an urgent and comparable investment in implementation science (ImS) research to strengthen the response to the HIV epidemic. Effective service delivery by HIV/AIDS programs and engagement in care among HIV-infected individuals will allow antiretroviral medications to reach their optimal public health impact. Makerere University College of Health Sciences (MakCHS) has collaborated with the University of California, San Francisco (UCSF) for over three decades on a range of scientific studies. We plan to leverage this foundation and build a multi-disciplinary team to create a world-class training program for ImS focused on delivery of HIV/AIDS services and engagement in care. Building on the findings of our planning grant, we propose a unique multi-disciplinary ImS research training program at Makerere University School of Medicine. The goals of the proposed program are to: 1) provide training and mentoring in the field of implementation science to Ugandan scholars 2) establish an ImS training site at Makerere University School of Medicine for Uganda and other institutions in Africa. The specific objectives of this training program are to: 1) strengthen the scientific leadership and expertise needed for implementation science research; 2) strengthen the sustainability of implementation science research at Makerere University by integrating ImS research into on-going capacity building programs; 3) promote collaborations between academic research institutions and faculty in Uganda and those in the US; 4) Strengthen trainee contributions to evidence-based decision making related to HIV prevention, care and treatment services through regular interactions with policy makers and HIV program implementers; 5) optimize training through utilization of additional available resources in Uganda (including projects funded by the NIH, PEPFAR and other international agencies); 6) strengthen research capacity in Uganda by helping trainees to integrate into Ugandan institutions and pursue independently-supported scientific careers; 7) create a Centre of Excellence for ImS at MakCHS to serve as a training site for other institutions in Africa. The proposed ImS training program will build on existing relationships between scientists at MakCHS and its affiliated HIV programs (medical), the Makerere University College of Humanities and Social Sciences (non-medical), UCSF and UCB. During our five year program, we anticipate training Ugandan trainees as follows: 2 candidates in master's degree programs at UCSF, 8 candidates in master's degree programs at Makerere University, 4 candidates in long-term non-degree training (including post-doc training), 20 candidates in a modular certificate program and over 700 candidates in short-term non-degree programs.

 描述（由申请人提供）：尽管乌干达已在艾滋病毒方案中投入了大量资源，但距离80%的普遍获得护理目标仍有很大差距。虽然乌干达在过去30年里在艾滋病毒、结核病和疟疾方面开展了非常成功的研究合作，但大部分工作都集中在临床研究上，研究结果并不总是转化为政策和实践的变化。目前，我们需要对实施科学（ImS）研究进行紧急且可比的投资，以加强对艾滋病毒流行病的应对。艾滋病毒/艾滋病方案提供的有效服务和艾滋病毒感染者的护理工作将使抗逆转录病毒药物发挥最佳的公共卫生影响。Makerere大学健康科学学院（MakCHS）与加州大学弗朗西斯科分校（UCSF）合作了三十多年，进行了一系列科学研究。我们计划利用这一基础，建立一个多学科的团队，为ImS创建一个世界一流的培训计划，重点是提供艾滋病毒/艾滋病服务和参与护理。基于我们的规划补助金的调查结果，我们提出了一个独特的多学科ImS研究培训计划在医学的Makerere大学学院。拟议方案的目标是：1）为乌干达学者提供实施科学领域的培训和指导; 2）在马凯雷雷大学医学院为乌干达和非洲其他机构建立ImS培训基地。该培训计划的具体目标是：1）加强实施科学研究所需的科学领导和专业知识; 2）通过将ImS研究纳入正在进行的能力建设计划，加强Makerere大学实施科学研究的可持续性; 3）促进乌干达和美国学术研究机构和教师之间的合作; 4）通过与决策者和艾滋病毒方案执行者的定期互动，加强受训人员对有关艾滋病毒预防、护理和治疗服务的循证决策的贡献; 5）通过利用乌干达的额外可用资源，优化培训（包括由美国国立卫生研究院、总统防治艾滋病紧急救援计划和其他国际机构资助的项目）; 6）通过帮助受训人员融入乌干达机构和追求独立支持的科学事业来加强乌干达的研究能力; 7）在MakCHS建立一个ImS英才中心，作为非洲其他机构的培训场所。拟议的ImS培训计划将建立在MakCHS及其附属艾滋病毒项目（医学），Makerere大学人文与社会科学学院（非医学），UCSF和UCB科学家之间的现有关系基础上。在我们的五年计划中，我们预计培训乌干达学员如下：2名在加州大学旧金山分校硕士学位课程的候选人，8名在马凯雷雷大学硕士学位课程的候选人，4名长期非学位培训（包括博士后培训）的候选人，20名在模块化证书课程的候选人和700多名短期非学位课程的候选人。