Training Program in Cancer Biology

项目摘要/摘要 此应用程序请求支持Sidney Kimmel癌症中心的癌症生物学培训计划 在托马斯·杰斐逊大学。该计划提供广泛的多学科博士后和博士后 了解癌症的发展、进展和治疗方面的培训。该计划将提供 学员对癌症有严谨的基本机理了解，并参与奠定基础 治疗癌症的转化性方法。此外，受训人员将与临床研究人员互动，以获得 深入了解癌症疗法的使用和基础研究成果的产生机制 送进诊所。该培训计划的导师包括专注于癌症的资深教职员工 研究项目和重要的指导经验以及专注于癌症的青少年核心群体 教职员工。相当多的导师参与翻译研究和临床试验活动，这些活动是 专注于癌症。这一独特的参与教职员工组合将通过直接指导提供培训 互动、专业教育活动和课程作业。 癌症生物学培训计划包括西德尼·基梅尔癌症中心的37名成员，来自12名成员 基础科室和临床科室。培训计划由联合首席调查员和 几个行政委员会。领导团队专注于为 不同种族和不同科学背景的受训干部。该计划将通过内部和 建立外部审查机制，以确保受训人员获得尽可能好的培训体验。 总体而言，该计划将为学员提供出色的职业发展，使他们能够从事依赖于职业的职业 在了解癌症的机制基础及其在癌症治疗中的应用后，它将提供一种 批判性团队教育经验在多学科性质的翻译研究和激发 学员积极考虑临床试验设计和临床研究活动。

Project Abstract/Summary This application requests support for a Training Program in Cancer Biology at the Sidney Kimmel Cancer Center at Thomas Jefferson University. This Program provides broad multidisciplinary pre-doctoral and postdoctoral training in understanding the development, progression and treatment of cancer. The Program will provide trainees with a rigorous basic mechanistic understanding of cancer and participation in laying the groundwork for translational approaches to treat cancer. In addition, trainees will interact with clinical researchers to gain insight into the use of cancer therapeutics and the mechanism through which basic research findings are brought into the clinic. Mentors in this Training Program include established faculty members that have cancer-focused research programs and significant experience in mentoring as well as a core group of cancer-focused junior faculty. A significant number of mentors are involved in translational research and clinical trials activities that are focused on cancer. This unique combination of participating faculty will provide training through direct mentoring interactions, specialized educational activities, and course work. The Training Program in Cancer Biology includes 37 members of the Sidney Kimmel Cancer Center from 12 basic and clinical departments. The Training Program is administered by the co-Principal Investigators and several Administrative Committees. The leadership team is focused on delivering training excellence to an ethnically and scientifically diverse cadre of trainees. The Program will be evaluated through both internal and external review mechanisms to ensure that the trainees are receiving the best possible training experience. Overall, this Program will provide outstanding career development for trainees to pursue careers dependent upon understanding the mechanistic basis of cancer and its application to cancer therapeutics; it will provide a critical team-based educational experience in the multi-disciplinary nature of translational research and stimulate the trainees to actively consider clinical trials design and clinical research activities.