Training Program in Cancer Biology

项目摘要/摘要 此申请要求对Sidney Kimmel癌症中心的癌症生物学培训计划提供支持 在托马斯杰斐逊大学。该计划提供广泛的多学科博士前和博士后 了解癌症的发展、进展和治疗的培训。该计划将提供 对癌症有严格的基本机械理解并参与奠定基础的学员 用于治疗癌症的转化方法。此外，学员将与临床研究人员互动， 深入了解癌症治疗方法的使用和基础研究发现带来的机制 进了诊所该培训计划中的导师包括以癌症为重点的既定教师 研究计划和指导的重要经验，以及一个核心小组的癌症为重点的初级 教师。大量导师参与转化研究和临床试验活动， 专注于癌症这种参与教师的独特组合将通过直接指导提供培训 互动，专门的教育活动和课程工作。 癌症生物学培训计划包括来自12个国家的37名Sidney Kimmel癌症中心成员。 基础和临床部门。培训计划由共同主要研究者管理， 几个行政委员会。领导团队专注于为客户提供卓越的培训， 在种族和科学方面具有多样性的受训干部。该计划将通过内部和 外部审查机制，以确保受训人员获得尽可能好的培训经验。 总体而言，该计划将为学员提供出色的职业发展， 在理解癌症的机制基础及其在癌症治疗中的应用后，它将提供一个 关键的团队为基础的教育经验，在翻译研究的多学科性质和刺激 学员积极考虑临床试验设计和临床研究活动。

Project Abstract/Summary This application requests support for a Training Program in Cancer Biology at the Sidney Kimmel Cancer Center at Thomas Jefferson University. This Program provides broad multidisciplinary pre-doctoral and postdoctoral training in understanding the development, progression and treatment of cancer. The Program will provide trainees with a rigorous basic mechanistic understanding of cancer and participation in laying the groundwork for translational approaches to treat cancer. In addition, trainees will interact with clinical researchers to gain insight into the use of cancer therapeutics and the mechanism through which basic research findings are brought into the clinic. Mentors in this Training Program include established faculty members that have cancer-focused research programs and significant experience in mentoring as well as a core group of cancer-focused junior faculty. A significant number of mentors are involved in translational research and clinical trials activities that are focused on cancer. This unique combination of participating faculty will provide training through direct mentoring interactions, specialized educational activities, and course work. The Training Program in Cancer Biology includes 37 members of the Sidney Kimmel Cancer Center from 12 basic and clinical departments. The Training Program is administered by the co-Principal Investigators and several Administrative Committees. The leadership team is focused on delivering training excellence to an ethnically and scientifically diverse cadre of trainees. The Program will be evaluated through both internal and external review mechanisms to ensure that the trainees are receiving the best possible training experience. Overall, this Program will provide outstanding career development for trainees to pursue careers dependent upon understanding the mechanistic basis of cancer and its application to cancer therapeutics; it will provide a critical team-based educational experience in the multi-disciplinary nature of translational research and stimulate the trainees to actively consider clinical trials design and clinical research activities.