Task Order One (1) shall encompass conduct of and support for student training and education activities, support for educational and training activities, and preparation of manuscripts.

任务令一 (1) 应包括开展和支持学生培训和教育活动、支持教育和培训活动以及准备稿件。

• 批准号: 10469962
• 负责人: MARINELLE PAYTON
• 金额: $ 107.75万
• 依托单位: JACKSON STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-13 至 2022-08-12
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10469962
• 关键词: Abdomen; African American; Aorta; Area; Atherosclerosis Risk in Communities; Back; Behavioral Genetics; Biochemical; Biological; Biological Assay; Biomedical Research; Candidate Disease Gene; Cardiac; Cardiovascular Diseases; Cardiovascular system; Communities; Community Health Education; County; Cryopreservation; DNA; Data; Data Collection; Data Set; Disease; Echocardiography; Education and Outreach; Educational Activities; Educational Status; Enrollment; Environmental Risk Factor; Future; Genetic Risk; Genome Scan; Investigation; Jackson Heart Study; Knowledge; Lymphocyte; Magnetic Resonance Imaging; Manuscripts; Mathematics; Measures; Mentorship; Participant; Population; Preparation; Psychosocial Factor; Publications; Research; Resources; Risk Factors; Sampling; Science; Scientist; Students; Training; Training Activity; Training Programs; Training and Education; Underrepresented Minority; X-Ray Computed Tomography; aged; base; biomedical profession; cardiovascular disorder epidemiology; cardiovascular disorder risk; cardiovascular health; career; cohort; college; community living; disorder risk; epidemiology study; graduate student; healthy lifestyle; heart imaging; high school; innovation; interest; metropolitan; minority undergraduate; novel; programs; recruit; social culture; socioeconomics; student training; undergraduate student; underrepresented minority student

The Jackson Heart Study (JHS), initiated in 1998, is a longitudinal investigation of genetic and environmental risk factors associated with the disproportionate burden of cardiovascular disease (CVD) in African-Americans. In addition, the JHS performs a variety of community education and outreach activities to promote healthy lifestyles and reduce disease risk burden. It also conducts college undergraduate and graduate-level training programs and high school science and math enrichment programs to prepare and encourage underrepresented minority students to pursue biomedical careers. (www.jacksonheartstudy.org/ ). The JHS represents an expansion of the Jackson Field Center of the Atherosclerosis Risk in Communities (ARIC) study (www2.cscc.unc.edu/aric/), to broaden data collection in an African- American population and to increase access to and participation of African American populations and scientists in biomedical research and professions. The study recruited 5306 African-American residents, including 3,732 residents also enrolled in ARIC, living in the Jackson, MS, metropolitan area of Hinds, Madison, and Rankin Counties. Enrolled JHS participants, initially aged 20 - 90 years, received three back-to-back examinations (Exam 1, 2000-04; Exam 2, 2005-08; and Exam 3, 2009-13) and have been contacted annually. Findings on the rich set of data on physical, behavioral, genetic, and psychosocial factors have been presented in over 345 publications as of the end of 2016. The wealth of data and biological samples collected since the study’s inception as well as the potential for new data collection from JHS participants offer vast opportunities for new scientific discoveries. Participant exams have produced extensive longitudinal data on traditional and putative CVD risk factors, socioeconomic and sociocultural factors, and biochemical analytes; and measures of subclinical disease from echocardiography, cardiac magnetic resonance imaging (MRI), and computed tomography (CT) scans of the heart, aorta, and abdomen. Stored biological samples have been assayed for putative biochemical risk factors and stored for future research. DNA has been extracted and lymphocytes cryopreserved for study of candidate genes, genome-wide scanning, expression, and other –omics investigations.

杰克逊心脏研究（JHS）于1998年启动，是一项与非裔美国人心血管疾病（CVD）不成比例负担相关的遗传和环境风险因素的纵向调查。此外，JHS还开展了各种社区教育和外展活动，以促进健康的生活方式和减少疾病风险负担。它还开展大学本科和研究生水平的培训计划，以及高中科学和数学丰富计划，以准备和鼓励未被充分代表的少数民族学生从事生物医学事业。(www.jacksonheartstudy.org/)。