Task Order One (1) shall encompass conduct of and support for student training and education activities, support for educational and training activities, and preparation of manuscripts.
Task Order One (1) shall encompass conduct of and support for student training and education activities, support for educational and training activities, and preparation of manuscripts.
批准号:
10683917
负责人:
MARINELLE PAYTON
金额:
$110.03万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2022
资助国家:
美国
项目状态:
已结题
起止时间:
2022-08-13 至 2023-08-12
关键词:
AbdomenAfrican AmericanAfrican American populationAortaAreaAtherosclerosis Risk in CommunitiesBackBehavioral GeneticsBiochemicalBiologicalBiological AssayBiomedical ResearchCandidate Disease GeneCardiovascular DiseasesCardiovascular systemCommunitiesCommunity Health EducationCountyCryopreservationDNADataData CollectionData SetDiseaseEchocardiographyEducation and OutreachEducational ActivitiesEducational StatusEnrollmentEnvironmental Risk FactorFutureGenetic RiskGenome ScanInvestigationJackson Heart StudyKnowledgeLymphocyteManuscriptsMathematicsMeasuresMentorshipParticipantPreparationPsychosocial FactorPublicationsResearchResourcesRisk FactorsSamplingScienceScientistStudentsTrainingTraining ActivityTraining ProgramsTraining and EducationUnderrepresented MinorityX-Ray Computed Tomographyagedbasebiomedical professioncardiac magnetic resonance imagingcardiovascular disorder epidemiologycardiovascular disorder riskcardiovascular healthcareercohortcollegecommunity livingdisorder riskepidemiology studygraduate studenthealthy lifestyleheart imaginghigh schoolinnovationinterestmetropolitanminority undergraduatenovelprogramsrecruitsocial culturesocioeconomicsstudent trainingundergraduate studentunderrepresented minority student
中文摘要
杰克逊心脏研究(JHS)始于1998年,是对与非裔美国人心血管疾病(CVD)负担不成比例相关的遗传和环境风险因素进行的纵向调查。此外,JHS还举办了各种社区教育和外展活动,以促进健康的生活方式和减少疾病风险负担。它还开展大学本科生和研究生水平的培训计划以及高中科学和数学充实计划,以准备和鼓励未被充分代表的少数民族学生从事生物医学职业。(www.jacksonHearStudy.org/)。
JHS代表了社区动脉粥样硬化风险研究(ARIC)研究的杰克逊·菲尔德中心(www.cscc.unc.edu/ARIC/)的扩展,以扩大非裔美国人人口的数据收集,并增加非裔美国人人口和科学家对生物医学研究和专业的接触和参与。这项研究招募了5306名非洲裔美国人,其中包括3732名也在ARIC注册的居民,他们生活在密苏里州杰克逊市、Hinds、Madison和Rankin县的大都市区。JHS的注册参与者最初年龄为20-90岁,他们接受了三次背靠背考试(考试1,2000-04;考试2,2005-08;考试3,2009-13),并每年都会得到联系。截至2016年底,关于身体、行为、遗传和心理社会因素的丰富数据集的研究结果已发表在345多份出版物上。
自研究开始以来收集的大量数据和生物样本,以及从JHS参与者那里收集新数据的潜力,为新的科学发现提供了巨大的机会。参与者检查产生了大量关于传统和假定的心血管疾病风险因素、社会经济和社会文化因素以及生化分析的纵向数据;以及通过心脏、主动脉和腹部的超声心动图、心脏磁共振成像(MRI)和计算机断层扫描(CT)对亚临床疾病的测量。已经对储存的生物样本进行了可能的生化风险因素检测,并储存起来以供将来研究。DNA被提取出来,淋巴细胞被冷冻保存,用于候选基因的研究、全基因组扫描、表达和其他组学研究。
英文摘要
The Jackson Heart Study (JHS), initiated in 1998, is a longitudinal investigation of genetic and environmental risk factors associated with the disproportionate burden of cardiovascular disease (CVD) in African-Americans. In addition, the JHS performs a variety of community education and outreach activities to promote healthy lifestyles and reduce disease risk burden. It also conducts college undergraduate and graduate-level training programs and high school science and math enrichment programs to prepare and encourage underrepresented minority students to pursue biomedical careers. (www.jacksonheartstudy.org/ ).
The JHS represents an expansion of the Jackson Field Center of the Atherosclerosis Risk in Communities (ARIC) study (www2.cscc.unc.edu/aric/), to broaden data collection in an African- American population and to increase access to and participation of African American populations and scientists in biomedical research and professions. The study recruited 5306 African-American residents, including 3,732 residents also enrolled in ARIC, living in the Jackson, MS, metropolitan area of Hinds, Madison, and Rankin Counties. Enrolled JHS participants, initially aged 20 - 90 years, received three back-to-back examinations (Exam 1, 2000-04; Exam 2, 2005-08; and Exam 3, 2009-13) and have been contacted annually. Findings on the rich set of data on physical, behavioral, genetic, and psychosocial factors have been presented in over 345 publications as of the end of 2016.
The wealth of data and biological samples collected since the study’s inception as well as the potential for new data collection from JHS participants offer vast opportunities for new scientific discoveries. Participant exams have produced extensive longitudinal data on traditional and putative CVD risk factors, socioeconomic and sociocultural factors, and biochemical analytes; and measures of subclinical disease from echocardiography, cardiac magnetic resonance imaging (MRI), and computed tomography (CT) scans of the heart, aorta, and abdomen. Stored biological samples have been assayed for putative biochemical risk factors and stored for future research. DNA has been extracted and lymphocytes cryopreserved for study of candidate genes, genome-wide scanning, expression, and other –omics investigations.
期刊论文(0)
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会议论文
JACKSON HEART STUDY (JHS) GRADUATE TRAINING AND EDUCATION CENTER (GTEC) - TASK AREA B
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批准号:10972975
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项目类别:
-
资助金额:$220.0万
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财政年份:2023
-
负责人:MARINELLE PAYTON
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依托单位:
Jackson Heart Study (JHS) Graduate Training and Education Center (GTEC) - Wynette Williams-Kirkwood Diversity Supplement
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批准号:10499095
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项目类别:
-
资助金额:$4.04万
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财政年份:2021
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负责人:MARINELLE PAYTON
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依托单位:
Jackson Heart Study (JHS) Graduate Training and Education Center (GTEC) - Kierra Jones Diversity Supplement
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批准号:10499098
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项目类别:
-
资助金额:$4.04万
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财政年份:2021
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负责人:MARINELLE PAYTON
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依托单位:
JACKSON HEART STUDY (JHS) GRADUATE TRAINING AND EDUCATION CENTER (GTEC) - SHEILA MALONE DIVERSITY SUPPLEMENT
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批准号:10721071
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项目类别:
-
资助金额:$4.04万
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财政年份:2021
-
负责人:MARINELLE PAYTON
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依托单位:
Jackson Heart Study (JHS) Graduate Training and Education Center (GTEC) - Sheila Malone Diversity Supplement
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批准号:10499086
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项目类别:
-
资助金额:$4.04万
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财政年份:2021
-
负责人:MARINELLE PAYTON
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依托单位:
JACKSON HEART STUDY (JHS) GRADUATE TRAINING AND EDUCATION CENTER (GTEC) - WYNETTE WILLIAMS-KIRKWOOD DIVERSITY SUPPLEMENT
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批准号:10721068
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项目类别:
-
资助金额:$4.04万
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财政年份:2021
-
负责人:MARINELLE PAYTON
-
依托单位:
JACKSON HEART STUDY (JHS) GRADUATE TRAINING AND EDUCATION CENTER (GTEC) - KIERRA JONES DIVERSITY SUPPLEMENT
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批准号:10721070
-
项目类别:
-
资助金额:$4.04万
-
财政年份:2021
-
负责人:MARINELLE PAYTON
-
依托单位:
Jackson Heart Study (JHS) Graduate Training and Education Center (GTEC) - Marcy Cage Diversity Supplement
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批准号:10499096
-
项目类别:
-
资助金额:$4.04万
-
财政年份:2021
-
负责人:MARINELLE PAYTON
-
依托单位:
JACKSON HEART STUDY (JHS) GRADUATE TRAINING AND EDUCATION CENTER (GTEC) - MARCY CAGE DIVERSITY SUPPLEMENT
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批准号:10721065
-
项目类别:
-
资助金额:$4.04万
-
财政年份:2021
-
负责人:MARINELLE PAYTON
-
依托单位:
Task Order One (1) shall encompass conduct of and support for student training and education activities, support for educational and training activities, and preparation of manuscripts.
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批准号:10469962
-
项目类别:
-
资助金额:$107.75万
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财政年份:2018
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负责人:MARINELLE PAYTON
-
依托单位:
海外基金