JACKSON HEART STUDY (JHS) GRADUATE TRAINING AND EDUCATION CENTER (GTEC) - MARCY CAGE DIVERSITY SUPPLEMENT

杰克逊心脏研究 (JHS) 研究生培训和教育中心 (GTEC) - 玛西·凯奇多样性补充材料

• 批准号: 10721065
• 负责人: MARINELLE PAYTON
• 金额: $ 4.04万
• 依托单位: JACKSON STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-30 至 2023-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10721065
• 关键词: African American; African American population; Age; Area; Blood Pressure; Blood coagulation; Body Size; Cholesterol; Clinic; Coronary artery; County; Diabetes Mellitus; Discrimination; Disease; Electrocardiogram; Enrollment; Family member; Genetic; Glucose; Habits; Height; Hypertension; Institutes; Institution; Investigation; Jackson Heart Study; Laboratories; Life Style; Lipids; Measurement; Medical History; Medical center; Mississippi; National Heart, Lung, and Blood Institute; Neck; Obesity; Participant; Pharmaceutical Preparations; Phase; Physical activity; Physical assessment; Physiological; Questionnaires; Risk Factors; Series; Site; Socioeconomic Status; Training and Education; United States National Institutes of Health; Universities; Weight; Woman; cohort; college; epidemiology study; falls; health disparity; men; metropolitan; minority health disparity; population based; prospective; pulmonary function; recruit; social; social culture; ultrasound

The Jackson Heart Study (JHS), the largest investigation of CVD undertaken in an African-American population, is a single-site prospective epidemiologic investigation in the Jackson, Mississippi metropolitan area of Hinds, Madison, and Rankin counties. The JHS is sponsored by the National Heart, Lung, and Blood Institute (NHLBI) and the National Institute of Minority Health and Health Disparities (NIMHD) at the National Institutes of Health (NIH). The JHS started as a partnership between three local institutions: Jackson State University, Tougaloo College, and the University of Mississippi Medical Center and recruited 5,306 African-American men and women between the ages of 35 and 84. Family members were included in order to permit studies of familial and genetic contributions to CVD. The initial examination phase of the study lasted from the fall of 2000 to March 2004 and involved an extensive examination that included a series of questionnaires (dealing with lifestyle habits, medical history, medications, social and cultural factors), physical assessments (height, weight, body size, blood pressure, electrocardiogram, ultrasound measurements of the heart and arteries in the neck, and lung function) and laboratory measurements (cholesterol and other lipids, glucose, indicators related to clotting of the blood, among others). The information collected in this study includes both conventional risk factors and new or emerging factors that may be related to CVD. It also included newer areas of focus comprising early indicators of disease, genetics, socio-cultural influences, such as socioeconomic status and discrimination, and physiological relations between common disorders such as high blood pressure, obesity and diabetes and their influence on CVD. Exam 2 was conducted between 2005 and 2008, and Exam 3 from 2009 to 2012. The next phase of the JHS extended from 2013-2018 and did not include a clinic exam.

杰克逊心脏研究（JHS）是在非洲裔美国人人群中进行的最大规模CVD研究，是在杰克逊、密西西比大都会区Hinds、麦迪逊和兰金县进行的一项单中心前瞻性流行病学研究。JHS由美国国立卫生研究院（NIH）的国家心肺血液研究所（NHLBI）和国家少数民族健康与健康差异研究所（NIMHD）赞助。JHS最初是三个当地机构之间的合作伙伴关系：杰克逊州立大学，图加洛学院和密西西比大学医学中心，招募了5,306名年龄在35岁至84岁之间的非洲裔美国人。纳入家庭成员是为了研究CVD的家族和遗传贡献。该研究的初步审查阶段从2000年秋季持续到2004年3月，涉及广泛的审查，包括一系列问卷调查（处理生活习惯、病史、药物、社会和文化因素），身体评估（身高、体重、体型、血压、心电图、心脏和颈部动脉的超声测量，和肺功能）和实验室测量（胆固醇和其他脂质、葡萄糖、与血液凝固相关的指标等）。本研究收集的信息包括传统的危险因素和可能与CVD相关的新的或新兴的因素。它还包括较新的重点领域，包括疾病的早期指标，遗传学，社会文化影响，如社会经济地位和歧视，以及常见疾病之间的生理关系，如高血压，肥胖和糖尿病及其对心血管疾病的影响。第二次考试于2005年至2008年进行，第三次考试于2009年至2012年进行。JHS的下一阶段从2013年延长到2018年，不包括临床检查。