2/2 Partnership for Native American Cancer Prevention

2/2 美洲原住民癌症预防合作伙伴关系

• 批准号: 10473921
• 负责人: MARGARET M BRIEHL
• 金额: $ 17.57万
• 依托单位: UNIVERSITY OF ARIZONA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10473921
• 关键词: Address; Age; Applications Grants; Arizona; Basic Science; Biological; Biomedical Research; Cancer Burden; Cancer Center; Cancer Death Rates; Cause of Death; Collaborations; Communities; Community Outreach; Comprehensive Cancer Center; Degree program; Development; Education; Education and Outreach; Educational Curriculum; Ethnic group; Evaluation; Evaluation Research; Faculty; Fostering; Funding; Goals; Grant; Institution; Intervention; Joints; Laboratories; Malignant Neoplasms; Malignant neoplasm of cervix uteri; Mentors; NCI Center for Cancer Research; National Cancer Institute; Native Americans; Navajo; Outcome; Pilot Projects; Population; Positioning Attribute; Publications; Race; Research; Research Personnel; Research Project Grants; Research Support; Research Training; Resource Sharing; Screening for cancer; Services; Students; Techniques; Training; Translating; Tribes; Trust; Underrepresented Populations; Underrepresented Students; United States; United States National Institutes of Health; Universities; Workforce Development; Writing; anticancer research; base; biomedical scientist; cancer education; cancer health disparity; cancer prevention; cancer survival; cancer therapy; career development; clinical practice; community engaged research; community engagement; community partnership; cultural competence; design; education research; expectation; experience; graduate student; health disparity populations; health equity; health inequalities; insight; malignant stomach neoplasm; outreach; programs; recruit; screening; socioeconomics; success; tribal Nation; tribal community; undergraduate student

PROJECT SUMMARY/ABSTRCT: OVERALL The Partnership for Native American Cancer Prevention (NACP) is uniquely positioned to address cancer health inequities in Native American communities. Cancer is the second leading cause of death for Native Americans over the age of 45 years. Despite improvements in cancer screening techniques and major developments in cancer treatment in past decades, tribal communities have not benefited equally from these advances. Further, the NIH recognizes that Native Americans have the lowest representation of all underrepresented groups in the biomedical research workforce, which contributes to the overall cancer health inequities for this population. NACP began in 2002 as a partnership between Northern Arizona University (NAU), as the institution serving underserved health disparity populations and underrepresented students, and the University of Arizona Cancer Center (UACC), as the Comprehensive Cancer Center. The overarching goals of NACP are to increase NAU's cancer research and UACC's cancer health disparities capacities by honoring existing and establishing new Native American community partnerships. To meet these goals, the following aims are proposed: Aim 1. Conduct Pilot Research Projects and Full Research Projects, which address Native American cancer disparities and reflect community concerns; Aim 2. Recruit and support Native American faculty focused on cancer research; Aim 3. Create a new shared resource called “Guiding U54 Investigator Development to Sustainability (GUIDeS)“ with the goal to facilitate the transition of NACP- affiliated, Early Stage Investigators/Junior Investigators to research independence; Aim 4. Expand and implement cancer disparities research education with a focus on Native American students across NAU/UA undergraduate and graduate programs; Aim 5. Integrate community engagement principles into all NACP activities, facilitating dissemination of the Partnership's research findings and the National Outreach Network's initiatives to Native American communities. To achieve these Aims, two Full and one Pilot project are proposed; two have Native American co-leaders. One of the Full projects and the Pilot project combine basic science and community engaged research to address gastric and cervical cancer; death rates for these cancers are higher in Native American populations. We propose Administrative, Planning and Evaluation, Research Education, Outreach and GUIDeS Cores to support the research projects and integrate activities across the Partnership. NAU and UACC commit institutional funds to support new projects and Native American investigators. New priorities in this proposal are community engaged research that will impact cancer screening rates, recruitment and mentoring of Native American early stage investigators, grant writing activities to sustain Native American-focused cancer disparities research and initiatives, and joint research education curricula to develop a stronger Native American biomedical workforce. By the end of the proposed funding period, NACP will move Native Americans in Arizona closer to cancer health equity.

项目概要/摘要：总体 美洲原住民癌症预防伙伴关系 (NACP) 在解决癌症方面具有独特的优势 美洲原住民社区的健康不平等。癌症是当地人的第二大死因 45岁以上的美国人。尽管癌症筛查技术和主要技术有所进步 过去几十年癌症治疗的发展，部落社区并没有平等地从中受益 进步。此外，美国国立卫生研究院 (NIH) 认识到美洲原住民在所有人群中的代表性最低。 生物医学研究队伍中代表性不足的群体，这有助于整体癌症健康 该人群的不平等。 NACP 成立于 2002 年，是北亚利桑那大学之间的合作伙伴关系 （NAU），作为服务于服务不足的健康差异人群和代表性不足的学生的机构，以及 亚利桑那大学癌症中心 (UACC)，作为综合癌症中心。首要的 NACP 的目标是通过以下方式提高 NAU 的癌症研究和 UACC 的癌症健康差异能力： 尊重现有的并建立新的美洲原住民社区伙伴关系。为了实现这些目标， 提出以下目标： 目标 1. 开展试点研究项目和全面研究项目，其中 解决美洲原住民癌症差异并反映社区关切；目标 2. 招募和支持 美国原住民教师专注于癌症研究；目标 3. 创建一个名为“Guiding U54 可持续发展研究者发展 (GUIDeS)”，目标是促进 NACP- 的过渡 附属的早期研究人员/初级研究人员以进行独立研究；目标 4. 扩展并 实施癌症差异研究教育，重点关注 NAU/UA 的美国原住民学生 本科和研究生课程；目标 5. 将社区参与原则纳入所有 NACP 活动，促进伙伴关系研究成果和国家外联网络的传播 美洲原住民社区的倡议。为了实现这些目标，需要实施两个完整项目和一个试点项目 建议的;两人都有美洲原住民共同领导人。完整项目和试点项目之一结合了基本 科学和社区参与针对胃癌和宫颈癌的研究；这些人的死亡率 美洲原住民的癌症发病率较高。我们提出行政、规划和评估， 支持研究项目和整合活动的研究教育、外展和指南核心 整个伙伴关系。 NAU 和 UACC 承诺机构资金支持新项目和 Native 美国调查人员。该提案中的新优先事项是社区参与的影响癌症的研究 筛选率、美洲原住民早期研究人员的招募和指导、资助写作活动 维持以美洲原住民为中心的癌症差异研究和倡议以及联合研究教育 培养更强大的美国原住民生物医学劳动力的课程。到拟议资金结束时 在此期间，NACP 将使亚利桑那州的美洲原住民更加接近癌症健康公平。