Administrative Core

行政核心

• 批准号: 10488634
• 负责人: MELISSA A. SIMON
• 金额: $ 31.79万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-17 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10488634
• 关键词: Acceleration; Address; Advanced Malignant Neoplasm; Advisory Committees; Annual Reports; Applications Grants; Benchmarking; Budgets; Cancer Research Project; Chicago; Clinical; Collaborations; Communication; Communities; Community Outreach; Comprehensive Cancer Center; Consultations; Decision Making; Development; Ensure; Evaluation; Foundations; Goals; Grant; Gynecologic; Individual; Infrastructure; Institution; Leadership; Malignant Female Reproductive System Neoplasm; Malignant Neoplasms; Mentorship; Mission; Monitor; Parents; Pathology; Performance; Play; Process; Productivity; Research; Research Activity; Research Infrastructure; Research Personnel; Research Project Grants; Resource Sharing; Resources; Role; Safety; Site; Structure; Time; Translational Research; Universities; cancer health disparity; community engagement; conflict resolution; data management; experience; health equity; infrastructure development; meetings; operation; programs; research and development; research facility; translational cancer research; translational pipeline

ABSTRACT This feasibility and planning proposal to develop the Northwestern University Cancer Health Equity Research SPORE (NU-CHERS) will generate scientific findings and establish sustainable, collaborative, academic and community infrastructure that will serve as the foundation for a comprehensive translational cancer research program focused on gynecologic cancer disparities. In order to accomplish these translational research and infrastructure development goals, the NU-CHERS Administrative Core (AC) will establish mechanisms and infrastructure that promote planning, communication, interaction, integration, and evaluation to support the broad spectrum of translational research activities for advancing cancer health equity. The Administrative Core has the following Specific Aims. Specific Aim 1: To oversee and support all NU-CHERS activities, ensuring integration, coordination, communication, and fiscal administration across the translational research projects (RP1, RP2), the Cores (Administrative Core, Gynecologic Biospecimen Pathology Core), and the Developmental Research Program (DRP). Specific Aim 2. To coordinate and maintain mechanisms to facilitate integration with, and efficient utilization of, existing institutional resources within the parent institutions Northwestern University and the Robert H. Lurie Comprehensive Cancer Center. Specific Aim 3: To establish and coordinate the structures, processes, and evaluation activities of the External Advisory Board (EAB) and Internal Advisory Board (IAB) for systematic, objective, iterative, and formal evaluation of the translational research productivity of NU-CHERS research projects, shared resource cores, and the DRP. The EAB will evaluate NU-CHERS performance against its broader mission and benchmark against practices and performance of SPORE sites. The IAB will advise the AC in program planning, inter-organizational relationships, and institutional commitment, to help ensure NU- CHERS achieves its overall aims. Specific Aim 4: To build a sustainable Community Advisory Board (CAB) connecting community institutions to translational gynecologic cancer disparities research that can provide consultation on community engagement strategies for NU-CHERS research projects, Cores, and the DRP. Specific Aim 5: To ensure effective and timely transition planning through initiation of multi-institutional, intra- and inter-SPORE scientific collaborations, grant application development, and mentorship of investigators to facilitate submission of a subsequent P50 SPORE grant.

抽象的 西北大学癌症健康公平研究的可行性和规划建议 SPORE (NU-CHERS) 将产生科学发现并建立可持续的、协作的、学术的和 社区基础设施将作为全面转化癌症研究的基础 计划重点关注妇科癌症差异。为了完成这些转化研究和 基础设施发展目标，NU-CHERS 行政核心 (AC) 将建立机制并 促进规划、沟通、互动、整合和评估的基础设施，以支持广泛的 促进癌症健康公平的一系列转化研究活动。行政核心有 遵循具体目标。具体目标 1：监督和支持所有 NU-CHERS 活动，确保整合、 跨转化研究项目（RP1、RP2）的协调、沟通和财务管理， 核心（行政核心、妇科生物样本病理学核心）和发展研究 计划（DRP）。具体目标 2. 协调和维护促进整合的机制，并 有效利用母校西北大学现有的机构资源 罗伯特·H·卢里综合癌症中心。具体目标 3：建立和协调结构， 外部顾问委员会 (EAB) 和内部顾问委员会 (IAB) 的流程和评估活动 对 NU-CHERS 转化研究生产力进行系统、客观、迭代和正式的评估 研究项目、共享资源核心和 DRP。 EAB 将评估 NU-CHERS 的表现 其更广泛的使命以及 SPORE 站点实践和性能的基准。 IAB 将建议 AC 参与计划规划、组织间关系和机构承诺，以帮助确保 NU- CHERS 实现了其总体目标。具体目标 4：建立可持续发展的社区咨询委员会 (CAB) 将社区机构与转化妇科癌症差异研究联系起来，可以提供 就 NU-CHERS 研究项目、核心和 DRP 的社区参与策略进行咨询。 具体目标 5：通过启动多机构、内部协调机制，确保有效和及时的过渡规划。 SPORE 之间的科学合作、资助申请开发以及对研究人员的指导 促进后续 P50 SPORE 拨款的提交。