Administrative Core

摘要 西北大学开展癌症健康公平性研究的可行性及规划建议 孢子(NU-cher)将产生科学发现，并建立可持续、协作、学术和 社区基础设施将作为全面转译癌症研究的基础 该计划侧重于妇科癌症的差异。为了完成这些翻译研究和 根据基础设施发展目标，新大学行政核心(AC)将建立机制和 促进规划、沟通、互动、集成和评估的基础设施，以支持广泛的 促进癌症健康公平的转化研究活动的范围。行政核心具有 遵循特定的目标。具体目标1：监督和支持国家卫生机构的所有活动，确保一体化， 跨翻译研究项目(RP1、RP2)的协调、沟通和财务管理， 核心(管理核心、妇科生物医学核心)和发展研究 程序(DRP)。具体目标2.协调和维持各种机制，以促进与 有效利用所属院校内现有的院校资源西北大学和 罗伯特·H·卢里综合癌症中心。具体目标3：建立和协调这些结构， 外部咨询委员会(EAB)和内部咨询委员会(IAB)的流程和评价活动 对护士翻译研究生产力的系统、客观、迭代和形式的评估 研究项目、共享资源核心和DRP。EAB将对NU-cher的表现进行评估 它的更广泛的使命和基准的做法和表现的孢子点。IAB将建议 AC在计划规划、组织间关系和机构承诺方面的作用，以帮助确保NU- CHERS达到了它的总体目标。具体目标4：建立一个可持续的社区咨询委员会(CAB) 将社区机构与转译妇科癌症差异研究联系起来，可以提供 就NU研究项目、核心和DRP的社区参与战略进行咨询。 具体目标5：通过启动多机构、内部和内部机制，确保有效和及时地进行过渡规划 和孢子间科学合作，资助应用程序开发，并指导研究人员 协助提交后续的P50孢子补助金。

ABSTRACT This feasibility and planning proposal to develop the Northwestern University Cancer Health Equity Research SPORE (NU-CHERS) will generate scientific findings and establish sustainable, collaborative, academic and community infrastructure that will serve as the foundation for a comprehensive translational cancer research program focused on gynecologic cancer disparities. In order to accomplish these translational research and infrastructure development goals, the NU-CHERS Administrative Core (AC) will establish mechanisms and infrastructure that promote planning, communication, interaction, integration, and evaluation to support the broad spectrum of translational research activities for advancing cancer health equity. The Administrative Core has the following Specific Aims. Specific Aim 1: To oversee and support all NU-CHERS activities, ensuring integration, coordination, communication, and fiscal administration across the translational research projects (RP1, RP2), the Cores (Administrative Core, Gynecologic Biospecimen Pathology Core), and the Developmental Research Program (DRP). Specific Aim 2. To coordinate and maintain mechanisms to facilitate integration with, and efficient utilization of, existing institutional resources within the parent institutions Northwestern University and the Robert H. Lurie Comprehensive Cancer Center. Specific Aim 3: To establish and coordinate the structures, processes, and evaluation activities of the External Advisory Board (EAB) and Internal Advisory Board (IAB) for systematic, objective, iterative, and formal evaluation of the translational research productivity of NU-CHERS research projects, shared resource cores, and the DRP. The EAB will evaluate NU-CHERS performance against its broader mission and benchmark against practices and performance of SPORE sites. The IAB will advise the AC in program planning, inter-organizational relationships, and institutional commitment, to help ensure NU- CHERS achieves its overall aims. Specific Aim 4: To build a sustainable Community Advisory Board (CAB) connecting community institutions to translational gynecologic cancer disparities research that can provide consultation on community engagement strategies for NU-CHERS research projects, Cores, and the DRP. Specific Aim 5: To ensure effective and timely transition planning through initiation of multi-institutional, intra- and inter-SPORE scientific collaborations, grant application development, and mentorship of investigators to facilitate submission of a subsequent P50 SPORE grant.