Short- and long-term health consequences of workers during consecutive days of heat stress

项目概要/摘要 Riana Pryor博士，ATC是一名运动科学家和临床医生，其职业目标是成为一名独立的运动科学家。 研究人员确定战略，尽量减少对工人健康的挑战性环境的影响， 安全为代价的候选人：普赖尔博士是加州大学运动与营养科学系的助理教授。 布法罗。她的研究探讨了在实验室和野外环境中进行体力活动时的热应变。培训内容： 拟议的职业发展计划将以她以前的经验为基础，以实现以下目标 培训目标：1）开发使用可穿戴技术的专业知识，以监测工人疲劳并防止 2）获得反复热暴露对人体健康影响的专业知识。大卫·霍斯勒博士 将担任她的主要导师与博士洛拉Cavuoto，扎卡里施拉德，和格雷戈里威尔丁四舍五入 导师团队研究：热应激增加肌肉骨骼损伤风险并降低生产力 由于疲劳、体温过高和脱水，这对多个诺拉工业部门（即， 农业、林业和渔业，建筑业，制造业，石油和天然气开采，公共安全， 运输、仓储和公用事业）。此外，重复使用会造成长期的健康后果。 现在才被阐明的热暴露。举个例子，越来越多的研究人员 连续几天的急性肾损伤是慢性肾病的促成因素。因此，有一个关键的 需要了解目前NIOSH对高温下工作的建议的程度 管理疲劳、体温过高和脱水，以尽量减少受伤和疾病。如果没有深思熟虑的进化， 这些建议，工人可能处于不必要的短期风险（例如，肌肉骨骼损伤）或 长期（例如，慢性肾病）有害健康后果。我们的研究将量化疲劳 在连续几天的高温下工作，同时遵守NIOSH的建议。二是 将确定连续热暴露对急性肾损伤生物标志物的影响。总结：这 该提案涉及NIOSH减少肌肉骨骼疾病和慢性病的战略目标。 我们讨论了NIOSH监测肌肉骨骼疾病风险因素的中期目标， 了解病因不明的慢性肾脏病。这些数据将为NIOSH的建议提供信息， 产生了多篇论文和演讲，以及未来R 01的初步数据， 在整个工作周中，热对工人健康造成压力。未来的研究将探索影响热应变的因素 完善预防战略。研究实践框架将被评估干预所接受 未来在实验室和现场环境中减少与热暴露相关的健康风险的有效性 补助金提交。成功的干预措施将被翻译和传播给工人执行 在工作场所。这个发展奖将使普赖尔博士扩大她的研究超越她的热应力 专业知识，使她成为一名独立的调查员，致力于提高工人的健康和安全。

PROJECT SUMMARY/ABSTRACT Riana Pryor, PhD, ATC is an exercise scientist and clinician with a career goal of becoming an independent investigator identifying strategies that minimize the impact of challenging environments on worker health and safety. Candidate: Dr. Pryor is an Assistant Professor of Exercise and Nutrition Sciences at the University at Buffalo. Her research explores heat strain during physical activity in laboratory and field settings. Training: The proposed career development plan will build upon her previous experience to achieve the following training aims: 1) develop expertise in the use of wearable technologies to monitor worker fatigue and prevent injury, and 2) acquire expertise in the impact of repeated heat exposures on human health. Dr. David Hostler will serve as her primary mentor with Drs. Lora Cavuoto, Zachary Schlader, and Gregory Wilding rounding out the mentorship team. Research: Heat stress increases musculoskeletal injury risk and reduces productivity due to fatigue, hyperthermia, and dehydration, which negatively impacts multiple NORA industry sectors (i.e., Agriculture, Forestry, and Fishing, Construction, Manufacturing, Oil and Gas Extraction, Public Safety, Transportation, Warehousing, and Utilities). Additionally, there are long term health consequences to repeated heat exposures that are only now being articulated. As an example, a growing body of research associates consecutive days of acute kidney injury as a contributor to chronic kidney disease. Therefore, there is a critical need to understand the degree to which current NIOSH recommendations for work in the heat adequately manage fatigue, hyperthermia, and dehydration to minimize injury and illness. Without thoughtful evolution of these recommendations, workers may be at unnecessary risk of short-term (e.g., musculoskeletal injury) or long-term (e.g., chronic kidney disease) deleterious health consequences. Our study will quantify fatigue during consecutive days of work in the heat while adhering to the NIOSH recommendations. Secondly, the impact of consecutive heat exposures on biomarkers of acute kidney injury will be determined. Summary: This proposal addresses the NIOSH strategic goals of reducing musculoskeletal disorders and chronic diseases. We address the NIOSH intermediate goal of monitoring risk factors for musculoskeletal disorders and understand chronic kidney disease of unknown etiology. These data will inform the NIOSH recommendations, resulting in multiple papers and presentations, and preliminary data for a future R01 examining the impact of heat strain on worker health throughout a work week. Future studies will explore factors impacting heat strain to refine prevention strategies. The research to practice framework will be embraced by evaluating intervention effectiveness to reduce health risks associated with heat exposures in laboratory and field settings in future grant submissions. Successful interventions will be translated and disseminated to workers for implementation in the workplace. This development award will allow Dr. Pryor to expand her research beyond her heat stress expertise, enabling her to become an independent investigator working to enhance worker health and safety.