Short- and long-term health consequences of workers during consecutive days of heat stress

项目摘要/摘要 Riana Pryor，ATC博士，运动科学家和临床医生，职业目标是成为一名独立的 调查员确定将具有挑战性的环境对员工健康的影响降至最低的策略 安全。候选人：普赖尔博士是该大学运动与营养科学的助理教授 水牛城。她的研究探索了实验室和野外环境中体力活动时的热应激。培训： 拟议的职业发展计划将以她以前的经验为基础，以实现以下目标 培训目标：1)培养使用可穿戴技术监测工人疲劳和预防疲劳的专门知识 2)获得有关反复高温暴露对人类健康影响的专业知识。大卫·霍斯特勒博士 将作为她的主要导师，洛拉·卡武托博士、扎克里·施拉德博士和格雷戈里·怀尔丁博士将继续担任她的导师 导师团队。研究：热应激增加肌肉骨骼损伤风险并降低生产力 由于疲劳、体温过高和脱水，这对多个Nora工业部门(即， 农业、林业和渔业、建筑、制造业、石油和天然气开采、公共安全、 运输、仓储和公用事业)。此外，反复服用也会造成长期的健康后果。 只是现在才被阐明的热暴露。例如，越来越多的研究助理 连续几天的急性肾损伤是慢性肾脏疾病的诱因。因此，有一个关键的 需要了解当前NIOSH建议在高温下工作的程度 控制疲劳、体温过高和脱水，将伤害和疾病降至最低。如果没有经过深思熟虑的进化 根据这些建议，工人可能面临不必要的短期风险(例如，肌肉骨骼损伤)或 长期的(如慢性肾脏疾病)有害健康后果。我们的研究将对疲劳进行量化 在连续几天的高温下工作，同时遵守NIOSH的建议。其次， 连续热暴露对急性肾损伤生物标志物的影响将被确定。摘要：此 该提案涉及NIOSH减少肌肉骨骼疾病和慢性病的战略目标。 我们致力于NIOSH的中间目标，即监测肌肉骨骼疾病的风险因素和 了解病因不明的慢性肾脏疾病。这些数据将为NIOSH的建议提供信息， 导致了多篇论文和演示文稿，以及未来R01审查的影响的初步数据 在一周的工作时间里，高温会给工人的健康带来压力。未来的研究将探索影响热应激的因素 完善预防策略。研究实践框架将通过评估干预措施来实现 未来在实验室和现场环境中减少与热暴露相关的健康风险的有效性 资助金申请。成功的干预措施将被翻译并分发给工人以供实施 在工作场所。这一发展奖将使普赖尔博士能够将她的研究扩展到她的热应激之外 专业知识，使她成为一名独立调查员，致力于提高工人的健康和安全。

PROJECT SUMMARY/ABSTRACT Riana Pryor, PhD, ATC is an exercise scientist and clinician with a career goal of becoming an independent investigator identifying strategies that minimize the impact of challenging environments on worker health and safety. Candidate: Dr. Pryor is an Assistant Professor of Exercise and Nutrition Sciences at the University at Buffalo. Her research explores heat strain during physical activity in laboratory and field settings. Training: The proposed career development plan will build upon her previous experience to achieve the following training aims: 1) develop expertise in the use of wearable technologies to monitor worker fatigue and prevent injury, and 2) acquire expertise in the impact of repeated heat exposures on human health. Dr. David Hostler will serve as her primary mentor with Drs. Lora Cavuoto, Zachary Schlader, and Gregory Wilding rounding out the mentorship team. Research: Heat stress increases musculoskeletal injury risk and reduces productivity due to fatigue, hyperthermia, and dehydration, which negatively impacts multiple NORA industry sectors (i.e., Agriculture, Forestry, and Fishing, Construction, Manufacturing, Oil and Gas Extraction, Public Safety, Transportation, Warehousing, and Utilities). Additionally, there are long term health consequences to repeated heat exposures that are only now being articulated. As an example, a growing body of research associates consecutive days of acute kidney injury as a contributor to chronic kidney disease. Therefore, there is a critical need to understand the degree to which current NIOSH recommendations for work in the heat adequately manage fatigue, hyperthermia, and dehydration to minimize injury and illness. Without thoughtful evolution of these recommendations, workers may be at unnecessary risk of short-term (e.g., musculoskeletal injury) or long-term (e.g., chronic kidney disease) deleterious health consequences. Our study will quantify fatigue during consecutive days of work in the heat while adhering to the NIOSH recommendations. Secondly, the impact of consecutive heat exposures on biomarkers of acute kidney injury will be determined. Summary: This proposal addresses the NIOSH strategic goals of reducing musculoskeletal disorders and chronic diseases. We address the NIOSH intermediate goal of monitoring risk factors for musculoskeletal disorders and understand chronic kidney disease of unknown etiology. These data will inform the NIOSH recommendations, resulting in multiple papers and presentations, and preliminary data for a future R01 examining the impact of heat strain on worker health throughout a work week. Future studies will explore factors impacting heat strain to refine prevention strategies. The research to practice framework will be embraced by evaluating intervention effectiveness to reduce health risks associated with heat exposures in laboratory and field settings in future grant submissions. Successful interventions will be translated and disseminated to workers for implementation in the workplace. This development award will allow Dr. Pryor to expand her research beyond her heat stress expertise, enabling her to become an independent investigator working to enhance worker health and safety.