South Carolina IDeA Networks of Biomedical Research Excellence (SC INBRE)

项目摘要 南卡罗来纳州IDEA生物医学研究卓越网络（SC INBRE）是一个全州范围的网络 由三所综合研究型大学（CRU）和十所重点本科院校组成 （PUI），其目标是加强生物医学研究基础设施，促进本科生 在南卡罗来纳州的研究培训，同时增加获得研究机会和职业生涯， 为代表性不足的少数民族和经济上处于不利地位的学生提供生物医学。科学主题 在SC INBRE中，来自南卡罗来纳州的研究专业知识，包括生物化学和 细胞/分子生物学、生物工程、生物医学工程、再生医学和神经科学。 随着“大数据”的兴起和个性化医疗的发展， 生物信息学有所发展。为了满足这一需求，SC INBRE的生物信息学核心提供研讨会 和实践培训机会，为教师和学生寻求应用生物信息学工具， research.在本供资周期内，自然科学理事会国家建筑研究所在实现这些目标方面取得了重大进展。 从2015年至2019年，415名学生在SC INBRE网络的生物医学研究实验室接受了培训。这些 学生中，39%是男性，61%是女性，总体上29%是代表性不足的少数民族。为学生 在此资助期间完成本科教育的人中，44%进入研究生院， 17%的人进入医疗/卫生专业学校，39%的人在行业中找到工作。SC INBRE教师和 在这一资助周期内，学生们发表了100多份出版物，并作了600多次演讲。他们的工作 从各种联邦和非联邦来源筹集了超过900万美元的校外资金。促进 机构间合作和促进研究文化在PUI，SC INBRE有助于 U 54合作奖，为南卡罗来纳州带来了1250万美元的研究资金。在下一个 在SC INBRE阶段，该网络在全州的覆盖范围将扩大到包括几个新的PUI， 长期的网络成员为这些新机构树立了榜样。开发研究 项目和生物信息学试点项目计划将继续支持教师驱动的研究和学生 训练SC INBRE将继续通过SC促进网络PUI的本科生研究培训 INRBE赞助的本科生研究计划，并建议扩大五个PUI的培训能力 通过改造现有空间/设施。将提供职业和专业发展活动 SC INBRE教师和学生，以及与SC建立网络和发展合作的机会 INBRE同事。在选定的SC INBRE机构制定的推广计划将使高中 教师和学生，加强管道的未来大学生感兴趣的生物医学研究 积极鼓励代表性不足的少数民族学生和来自 南卡罗来纳州的贫困地区。

Project Summary The South Carolina IDeA Networks of Biomedical Research Excellence (SC INBRE) is a state-wide network comprised of three Comprehensive Research Universities (CRUs) and ten Primarily Undergraduate Institutions (PUIs) whose goals are to enhance the biomedical research infrastructure and promote undergraduate research training in South Carolina while increasing access to research opportunities and careers in biomedicine for underrepresented minorities and economically disadvantaged students. The scientific themes in SC INBRE emerge from the research expertise in South Carolina and include Biochemistry and Cell/Molecular Biology, Bioengineering, Biomedical Engineering, Regenerative Medicine, and Neuroscience. With the rise of “big data” and a move towards personalized medicine, the need for research and training in Bioinformatics has increased. To meet this demand, the Bioinformatics Core of SC INBRE provides workshops and hands-on training opportunities for faculty and students seeking to apply bioinformatics tools to their research. During the current funding cycle, SC INBRE made significant progress in addressing these goals. From 2015-2019, 415 students were trained in biomedical research labs in the SC INBRE network. Of these students, 39% were male, 61% female and overall 29% were underrepresented minorities. For the students who completed their undergraduate education during this funding period, 44% enrolled in graduate school, 17% went to medical/health professional school, and 39% obtained a job industry. SC INBRE faculty and students produced over 100 publications and gave over 600 presentations during this funding cycle. Their work led to over $9 million dollars in extramural funding from a variety of federal and non-federal sources. Fostering inter-institutional collaborations and promoting a research culture at PUIs, SC INBRE contributed to a collaborative U54 award which brings $12.5 million in research dollars to South Carolina. During the next phase of SC INBRE, the network’s reach across the state will be expanded to include several new PUIs, with long-time network members serving a role models for these new institutions. The Developmental Research Project and Bioinformatics Pilot Project programs will continue to support faculty-driven research and student training. SC INBRE will continue to promote undergraduate research training at network PUIs through SC INRBE-sponsored Undergraduate Research Programs and proposes to expand training capacity at five PUIs through renovation of existing space/facilities. Career and professional development activities will be provided to SC INBRE faculty and students, as well as opportunities to network and develop collaborations with SC INBRE colleagues. Outreach programs developed at selected SC INBRE institutions will engage high school teachers and students, strengthening the pipeline of future college students interested in biomedical research careers and actively encouraging participation by underrepresented minority students and those from underserved areas in South Carolina.