Administrative Core

项目摘要/摘要-行政核心行政核心将为我们的药物组合提供领导、科学监督、治理和行政支持，以绕过耐药性和敏感性中心(D2CR-DRSC)，以确保D2CR-DRSC项目的有效运营、沟通、内部和外部合作、合规性和严格的科学评估。联席PD/联系人Pi Jeffrey Tyner和Co-PD/PI Brian Druker将担任行政核心的联席领导，并将由一名科学业务负责人Cristina Tognon、一名协作经理Pierrette Lo和一名研究和财务署长Sarah Bowden提供支持。管理核心的具体目标是：1)为D2CR-DRSC提供科学和行政领导、管理和支持，以确保有效整合所有项目、评估中心进展、共享标本和数据、以及内部沟通和运作绩效；以及2)提供科学和行政领导，以优化D2CR-DRSC与耐药性和敏感性网络的沟通和合作，以确保有效参与跨DRSC、NCI活动和研究社区。为实现这些目标，行政核心将建立和实施D2CR-DRSC治理，包括设立内部咨询小组和外部咨询委员会，以帮助评价中心在实现其目标和里程碑方面的进展情况；制定和遵循政策，确保及时发布和共享标本和数据；规划定期战略互动和会议；制定沟通计划；确保预算监督和遵守；管理知识产权问题；完成年度进度报告；促进与国家预防犯罪中心、DRSc指导委员会和网络中其他四个DRSC的沟通、协作和数据和资源共享；并履行支持D2CR-DRSc及其成功参与耐药性和敏感性网络所需的所有其他行政职责。

PROJECT SUMMARY/ABSTRACT – Administrative Core The Administrative Core will provide leadership, scientific oversight, governance, and administrative support to our Drug Combinations to Circumvent Resistance-Drug Resistance and Sensitivity Center (D2CR-DRSC) to ensure effective operations, communication, internal and external collaborations, compliance and rigorous scientific evaluation of D2CR-DRSC projects. Co-PD/Contact PI Jeffrey Tyner and Co-PD/PI Brian Druker will serve as Co-Leaders of the Administrative Core and will be supported by a Scientific Operations Leader, Cristina Tognon; a Collaborations Manager, Pierrette Lo; and a Research and Finance Administrator, Sarah Bowden. The Specific Aims of the Administrative Core are to: 1) provide scientific and administrative leadership, governance, and support to the D2CR-DRSC to ensure effective integration of all projects, evaluation of center progress, sharing of specimens and data, and internal communication and operational performance, and 2) provide scientific and administrative leadership to optimize the D2CR-DRSC’s communication and collaborations with the Drug Resistance and Sensitivity Network to ensure productive participation in cross-DRSC, NCI activities and the research community. To achieve these aims, the Administrative Core will establish and implement D2CR-DRSC governance, including establishing an Internal Advisory Group and an External Advisory Board to help evaluate the Center’s progress toward its aims and milestones; develop and follow policy to ensure timely release and sharing of specimens and data; plan regular strategic interactions and meetings; develop communications plans; ensure budget oversight and compliance; manage intellectual property issues; complete annual progress reports; facilitate communication, collaboration and data and resource sharing with the NCI, the DRSC Steering Committee, and the four other DRSCs in the Network; and perform all other administrative duties required to support the D2CR-DRSC and its successful participation in the Drug Resistance and Sensitivity Network.