Undergraduate Cardiovascular Research Program

总结 这个新的R25计划旨在让本科生参与多学科的翻译 心血管研究，旨在诊断、治疗和预防心血管疾病 （CVD）。代表性不足的少数种族/族裔、残疾人和残疾人人数太少， 来自农村和市中心的正在从事CVD研究的人（所有人都得到NHLBI的认可） 工作队审查研究培训和职业发展方案）。该计划旨在 让这些背景的学生参与多学科的研究活动，以减轻他们的负担。 CVD。我们的5年计划将每年招收12名大二学生进入一个多年的承诺， 将NIH的暑期研究津贴与教育课程相结合 由每个学生在弗吉尼亚州的高等教育的本科院校（包括历史上）的支持， 弗吉尼亚联邦大学（VCU）的研究优势- 包括NIH临床和转化科学奖和VCU保利心脏中心。关键特征 这项拟议的R25计划包括：1）将每个受训者与一位受资助的研究导师配对， 研究重点是CVD; 2）优秀的多学科教师谁是经验丰富的导师; 3）获得 来自NIH资助的主要基础科学、前瞻性队列研究的多种表型和生物材料，或 通过支持计划教师在VCU的临床试验; 4）现有课程提供 本科生，研究生和医学院的教师，以补充心血管疾病的研究领域，以前没有 5）两个机构研讨会系列，加强与其他机构的互动， 来自多个学科的学生和个人。一组种族和性别多样化的教师从六（6） 将成为拟议计划一部分的大学已经有指导12名学生的经验， 上一年的成功和可比方案。所有教师都有NIH或VA校外或其他同行- 审查供资情况;强有力的机构支持（财政资源、设施和设备）; 与VCU健康差异中心整合，以招募和培训少数民族;以及 支持关键的专业发展活动，如演讲和赠款和手稿写作。 这个R25计划的最终目标是吸引和培养一批优秀的年轻学生从六个 (6)弗吉尼亚州内的本科院校成为流畅的心血管疾病的最新发展 多学科的转化研究，谁将做好准备，追求未来的事业心血管 健康实现这一目标将增加代表性不足的种族/族裔 少数民族、残疾人以及农村和城市中心社区的人进入研究生课程， 项目重点是开发多学科转化研究的新进展， 预防心血管疾病，这是一个重大的公共卫生问题。

Summary This new R25 program is designed to engage undergraduate students in multi-disciplinary translational cardiovascular research directed toward the diagnosis, treatment and prevention of cardiovascular disease (CVD). There are too few under-represented racial/ethnic minorities, individuals with disabilities, and people from rural and inner-city locations who are pursuing careers in CVD research (all recognized by the NHLBI task force review of research training and career development programs). This program is designed to involve students from these backgrounds in multi-disciplinary research activities to reduce the burden of CVD. Our 5-year proposal will enroll 12 sophomore students each year into a multi-year commitment that combines the summer research stipend from this proposed NIH award with an educational curriculum supported by each student’s undergraduate institution of higher learning in Virginia (including historically minority-serving universities), and the research strengths of Virginia Commonwealth University (VCU) – including an NIH Clinical and Translational Science Award and the VCU Pauley Heart Center. Key features of this proposed R25 program include: 1) pairing each trainee with a funded research mentor whose research focuses on CVD; 2) outstanding multidisciplinary faculty who are seasoned mentors; 3) access to multiple phenotypic and biologic materials from major NIH-funded basic science, prospective cohort, or clinical trials at VCU through the supporting program faculty; 4) courses provided by the existing undergraduate, graduate, and medical school faculty to supplement areas of CVD research not previously experienced by students; and 5) two institutional seminar series that enhance interactions with other students and individuals from multiple disciplines. A group of racially and gender diverse faculty from six (6) universities who will be a part of the proposed program already have experience mentoring 12 students in a successful and comparable program in the prior year. All faculty have NIH or VA extramural or other peer- reviewed funding; strong institutional support (financial resources, facilities, and equipment); robust integration with the VCU Center of Health Disparities for recruiting and training minority individuals; and support for key professional development activities such as presentations and grant and manuscript writing. The ultimate goal of this R25 program is to attract and train a cohort of outstanding young students from six (6) undergraduate institutions within Virginia to become fluent in the latest developments of CVD multidisciplinary translational research, who will be well prepared to pursue future careers in cardiovascular health. Accomplishing this goal would augment the number of under-represented racial/ethnic minorities, those with disabilities and persons from rural and inner-city communities into graduate programs focused on developing new advances in multi-disciplinary translational research to treat and prevent cardiovascular disease, a major public health issue.